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SLCO1B1 (solute carrier organic anion transporter family member 1B1)

Identity

Other namesHBLRR
LST-1
LST1
OATP-C
OATP1B1
OATP2
OATPC
SLC21A6
HGNC (Hugo) SLCO1B1
LocusID (NCBI) 10599
Atlas_Id 51592
Location 12p12.2
Location_base_pair Starts at 21284128 and ends at 21392730 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EIF3A (10q26.11) / SLCO1B1 (12p12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLCO1B1   10959
Cards
Entrez_Gene (NCBI)SLCO1B1  10599  solute carrier organic anion transporter family member 1B1
GeneCards (Weizmann)SLCO1B1
Ensembl hg19 (Hinxton)ENSG00000134538 [Gene_View]  chr12:21284128-21392730 [Contig_View]  SLCO1B1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000134538 [Gene_View]  chr12:21284128-21392730 [Contig_View]  SLCO1B1 [Vega]
ICGC DataPortalENSG00000134538
TCGA cBioPortalSLCO1B1
AceView (NCBI)SLCO1B1
Genatlas (Paris)SLCO1B1
WikiGenes10599
SOURCE (Princeton)SLCO1B1
Genomic and cartography
GoldenPath hg19 (UCSC)SLCO1B1  -     chr12:21284128-21392730 +  12p12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLCO1B1  -     12p12.2   [Description]    (hg38-Dec_2013)
EnsemblSLCO1B1 - 12p12.2 [CytoView hg19]  SLCO1B1 - 12p12.2 [CytoView hg38]
Mapping of homologs : NCBISLCO1B1 [Mapview hg19]  SLCO1B1 [Mapview hg38]
OMIM237450   604843   
Gene and transcription
Genbank (Entrez)AB026257 AF060500 AF205071 AJ132573 AK312970
RefSeq transcript (Entrez)NM_006446
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_011745 NT_009714 NW_004929383
Consensus coding sequences : CCDS (NCBI)SLCO1B1
Cluster EST : UnigeneHs.449738 [ NCBI ]
CGAP (NCI)Hs.449738
Alternative Splicing GalleryENSG00000134538
Gene ExpressionSLCO1B1 [ NCBI-GEO ]   SLCO1B1 [ EBI - ARRAY_EXPRESS ]   SLCO1B1 [ SEEK ]   SLCO1B1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLCO1B1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10599
GTEX Portal (Tissue expression)SLCO1B1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6L6 (Uniprot)
NextProtQ9Y6L6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6L6
Splice isoforms : SwissVarQ9Y6L6 (Swissvar)
PhosPhoSitePlusQ9Y6L6
Domaine pattern : Prosite (Expaxy)KAZAL_2 (PS51465)    MFS (PS50850)   
Domains : Interpro (EBI)Kazal_dom    MFS_dom    OA_transporter   
Domain families : Pfam (Sanger)Kazal_2 (PF07648)    OATP (PF03137)   
Domain families : Pfam (NCBI)pfam07648    pfam03137   
Domain families : Smart (EMBL)KAZAL (SM00280)  
DMDM Disease mutations10599
Blocks (Seattle)SLCO1B1
SuperfamilyQ9Y6L6
Human Protein AtlasENSG00000134538
Peptide AtlasQ9Y6L6
HPRD09214
IPIIPI00295376   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6L6
IntAct (EBI)Q9Y6L6
FunCoupENSG00000134538
BioGRIDSLCO1B1
STRING (EMBL)SLCO1B1
ZODIACSLCO1B1
Ontologies - Pathways
QuickGOQ9Y6L6
Ontology : AmiGOplasma membrane  integral component of plasma membrane  bile acid metabolic process  bile acid transmembrane transporter activity  bile acid transmembrane transporter activity  sodium-independent organic anion transmembrane transporter activity  thyroid hormone transmembrane transporter activity  organic anion transport  bile acid and bile salt transport  membrane  basolateral plasma membrane  sodium-independent organic anion transport  sodium-independent organic anion transport  thyroid hormone transport  
Ontology : EGO-EBIplasma membrane  integral component of plasma membrane  bile acid metabolic process  bile acid transmembrane transporter activity  bile acid transmembrane transporter activity  sodium-independent organic anion transmembrane transporter activity  thyroid hormone transmembrane transporter activity  organic anion transport  bile acid and bile salt transport  membrane  basolateral plasma membrane  sodium-independent organic anion transport  sodium-independent organic anion transport  thyroid hormone transport  
Pathways : KEGGBile secretion   
NDEx Network
Atlas of Cancer Signalling NetworkSLCO1B1
Wikipedia pathwaysSLCO1B1
Orthology - Evolution
OrthoDB10599
GeneTree (enSembl)ENSG00000134538
Phylogenetic Trees/Animal Genes : TreeFamSLCO1B1
Homologs : HomoloGeneSLCO1B1
Homology/Alignments : Family Browser (UCSC)SLCO1B1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerSLCO1B1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLCO1B1
dbVarSLCO1B1
ClinVarSLCO1B1
1000_GenomesSLCO1B1 
Exome Variant ServerSLCO1B1
ExAC (Exome Aggregation Consortium)SLCO1B1 (select the gene name)
Genetic variants : HAPMAP10599
Genomic Variants (DGV)SLCO1B1 [DGVbeta]
Mutations
ICGC Data PortalSLCO1B1 
TCGA Data PortalSLCO1B1 
Broad Tumor PortalSLCO1B1
OASIS PortalSLCO1B1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLCO1B1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Pharmacogenomics of Infectious Diseases (PGx_IfD )
BioMutasearch SLCO1B1
DgiDB (Drug Gene Interaction Database)SLCO1B1
DoCM (Curated mutations)SLCO1B1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLCO1B1 (select a term)
intoGenSLCO1B1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:21284128-21392730  ENSG00000134538
CONAN: Copy Number AnalysisSLCO1B1 
Mutations and Diseases : HGMDSLCO1B1
OMIM237450    604843   
MedgenSLCO1B1
Genetic Testing Registry SLCO1B1
NextProtQ9Y6L6 [Medical]
TSGene10599
GENETestsSLCO1B1
Huge Navigator SLCO1B1 [HugePedia]
snp3D : Map Gene to Disease10599
BioCentury BCIQSLCO1B1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10599
Chemical/Pharm GKB GenePA134865839
Clinical trialSLCO1B1
Miscellaneous
canSAR (ICR)SLCO1B1 (select the gene name)
Probes
Litterature
PubMed247 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLCO1B1
EVEXSLCO1B1
GoPubMedSLCO1B1
iHOPSLCO1B1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 8 19:06:24 CEST 2016

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