Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SLCO2A1 (solute carrier organic anion transporter family member 2A1)

Identity

Alias (NCBI)MATR1
OATP2A1
PGT
PHOAR2
SLC21A2
HGNC (Hugo) SLCO2A1
HGNC Alias symbPGT
OATP2A1
HGNC Previous nameSLC21A2
 MATR1
HGNC Previous namesolute carrier family 21 (prostaglandin transporter), member 2
 matrin F/G 1
 solute carrier organic anion transporter family, member 2A1
LocusID (NCBI) 6578
Atlas_Id 54642
Location 3q22.1  [Link to chromosome band 3q22]
Location_base_pair Starts at 133932701 and ends at 134029925 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LOC100507412 (-) / SLCO2A1 (3q22.1)MGLL (3q21.3) / SLCO2A1 (3q22.1)SLCO2A1 (3q22.1) / DAG1 (3p21.31)
SLCO2A1 (3q22.1) / GUCA1C (3q13.13)SLCO2A1 (3q22.1) / RREB1 (6p24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SLCO2A1   10955
LRG (Locus Reference Genomic)LRG_841
Cards
Entrez_Gene (NCBI)SLCO2A1    solute carrier organic anion transporter family member 2A1
AliasesMATR1; OATP2A1; PGT; PHOAR2; 
SLC21A2
GeneCards (Weizmann)SLCO2A1
Ensembl hg19 (Hinxton)ENSG00000174640 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174640 [Gene_View]  ENSG00000174640 [Sequence]  chr3:133932701-134029925 [Contig_View]  SLCO2A1 [Vega]
ICGC DataPortalENSG00000174640
TCGA cBioPortalSLCO2A1
AceView (NCBI)SLCO2A1
Genatlas (Paris)SLCO2A1
SOURCE (Princeton)SLCO2A1
Genetics Home Reference (NIH)SLCO2A1
Genomic and cartography
GoldenPath hg38 (UCSC)SLCO2A1  -     chr3:133932701-134029925 -  3q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLCO2A1  -     3q22.1   [Description]    (hg19-Feb_2009)
GoldenPathSLCO2A1 - 3q22.1 [CytoView hg19]  SLCO2A1 - 3q22.1 [CytoView hg38]
ImmunoBaseENSG00000174640
genome Data Viewer NCBISLCO2A1 [Mapview hg19]  
OMIM601460   614441   
Gene and transcription
Genbank (Entrez)AK303550 AK309561 BC041140 BC051347 BU783445
RefSeq transcript (Entrez)NM_005630
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLCO2A1
Alternative Splicing GalleryENSG00000174640
Gene ExpressionSLCO2A1 [ NCBI-GEO ]   SLCO2A1 [ EBI - ARRAY_EXPRESS ]   SLCO2A1 [ SEEK ]   SLCO2A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLCO2A1 [ Firebrowse - Broad ]
GenevisibleExpression of SLCO2A1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6578
GTEX Portal (Tissue expression)SLCO2A1
Human Protein AtlasENSG00000174640-SLCO2A1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92959   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92959  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92959
Splice isoforms : SwissVarQ92959
PhosPhoSitePlusQ92959
Domaine pattern : Prosite (Expaxy)KAZAL_2 (PS51465)    MFS (PS50850)   
Domains : Interpro (EBI)Kazal_dom    Kazal_dom_sf    MFS_dom    MFS_trans_sf    OATP   
Domain families : Pfam (Sanger)Kazal_2 (PF07648)    OATP (PF03137)   
Domain families : Pfam (NCBI)pfam07648    pfam03137   
Conserved Domain (NCBI)SLCO2A1
Blocks (Seattle)SLCO2A1
PDB (RSDB)3MRR   
PDB Europe3MRR   
PDB (PDBSum)3MRR   
PDB (IMB)3MRR   
Structural Biology KnowledgeBase3MRR   
SCOP (Structural Classification of Proteins)3MRR   
CATH (Classification of proteins structures)3MRR   
SuperfamilyQ92959
Human Protein Atlas [tissue]ENSG00000174640-SLCO2A1 [tissue]
Peptide AtlasQ92959
HPRD03269
IPIIPI00295132   IPI00797664   IPI00946964   
Protein Interaction databases
DIP (DOE-UCLA)Q92959
IntAct (EBI)Q92959
BioGRIDSLCO2A1
STRING (EMBL)SLCO2A1
ZODIACSLCO2A1
Ontologies - Pathways
QuickGOQ92959
Ontology : AmiGOlipid transporter activity  plasma membrane  integral component of plasma membrane  lipid transport  prostaglandin transmembrane transporter activity  prostaglandin transmembrane transporter activity  sodium-independent organic anion transmembrane transporter activity  prostaglandin transport  membrane  sodium-independent organic anion transport  sodium-independent organic anion transport  transmembrane transport  
Ontology : EGO-EBIlipid transporter activity  plasma membrane  integral component of plasma membrane  lipid transport  prostaglandin transmembrane transporter activity  prostaglandin transmembrane transporter activity  sodium-independent organic anion transmembrane transporter activity  prostaglandin transport  membrane  sodium-independent organic anion transport  sodium-independent organic anion transport  transmembrane transport  
NDEx NetworkSLCO2A1
Atlas of Cancer Signalling NetworkSLCO2A1
Wikipedia pathwaysSLCO2A1
Orthology - Evolution
OrthoDB6578
GeneTree (enSembl)ENSG00000174640
Phylogenetic Trees/Animal Genes : TreeFamSLCO2A1
HOGENOMQ92959
Homologs : HomoloGeneSLCO2A1
Homology/Alignments : Family Browser (UCSC)SLCO2A1
Gene fusions - Rearrangements
Fusion : MitelmanMGLL/SLCO2A1 [3q21.3/3q22.1]  
Fusion : MitelmanSLCO2A1/GUCA1C [3q22.1/3q13.13]  
Fusion : QuiverSLCO2A1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLCO2A1 [hg38]
dbVarSLCO2A1
ClinVarSLCO2A1
MonarchSLCO2A1
1000_GenomesSLCO2A1 
Exome Variant ServerSLCO2A1
GNOMAD BrowserENSG00000174640
Varsome BrowserSLCO2A1
Genomic Variants (DGV)SLCO2A1 [DGVbeta]
DECIPHERSLCO2A1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLCO2A1 
Mutations
ICGC Data PortalSLCO2A1 
TCGA Data PortalSLCO2A1 
Broad Tumor PortalSLCO2A1
OASIS PortalSLCO2A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLCO2A1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLCO2A1
Mutations and Diseases : HGMDSLCO2A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch SLCO2A1
DgiDB (Drug Gene Interaction Database)SLCO2A1
DoCM (Curated mutations)SLCO2A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLCO2A1 (select a term)
intoGenSLCO2A1
Cancer3DSLCO2A1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601460    614441   
Orphanet2542   
DisGeNETSLCO2A1
MedgenSLCO2A1
Genetic Testing Registry SLCO2A1
NextProtQ92959 [Medical]
GENETestsSLCO2A1
Target ValidationSLCO2A1
Huge Navigator SLCO2A1 [HugePedia]
ClinGenSLCO2A1
Clinical trials, drugs, therapy
MyCancerGenomeSLCO2A1
Protein Interactions : CTD
Pharm GKB GenePA35840
PharosQ92959
Clinical trialSLCO2A1
Miscellaneous
canSAR (ICR)SLCO2A1 (select the gene name)
HarmonizomeSLCO2A1
DataMed IndexSLCO2A1
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSLCO2A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:46:31 CET 2021
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