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SLCO6A1 (solute carrier organic anion transporter family member 6A1)

Identity

Alias_namessolute carrier organic anion transporter family
Alias_symbol (synonym)OATP6A1
OATPY
MGC26949
CT48
Other aliasGST
OATP-I
HGNC (Hugo) SLCO6A1
LocusID (NCBI) 133482
Atlas_Id 55146
Location 5q21.1  [Link to chromosome band 5q21]
Location_base_pair Starts at 102371782 and ends at 102499016 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RAD51D (17q12) / SLCO6A1 (5q21.1)RAD51D 17q12 / SLCO6A1 5q21.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(5;17)(q21;q12) RAD51D/SLCO6A1


External links

Nomenclature
HGNC (Hugo)SLCO6A1   23613
Cards
Entrez_Gene (NCBI)SLCO6A1  133482  solute carrier organic anion transporter family member 6A1
AliasesCT48; GST; OATP-I; OATP6A1; 
OATPY
GeneCards (Weizmann)SLCO6A1
Ensembl hg19 (Hinxton)ENSG00000205359 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000205359 [Gene_View]  ENSG00000205359 [Sequence]  chr5:102371782-102499016 [Contig_View]  SLCO6A1 [Vega]
ICGC DataPortalENSG00000205359
TCGA cBioPortalSLCO6A1
AceView (NCBI)SLCO6A1
Genatlas (Paris)SLCO6A1
WikiGenes133482
SOURCE (Princeton)SLCO6A1
Genetics Home Reference (NIH)SLCO6A1
Genomic and cartography
GoldenPath hg38 (UCSC)SLCO6A1  -     chr5:102371782-102499016 -  5q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLCO6A1  -     5q21.1   [Description]    (hg19-Feb_2009)
EnsemblSLCO6A1 - 5q21.1 [CytoView hg19]  SLCO6A1 - 5q21.1 [CytoView hg38]
Mapping of homologs : NCBISLCO6A1 [Mapview hg19]  SLCO6A1 [Mapview hg38]
OMIM613365   
Gene and transcription
Genbank (Entrez)AF505657 AK131445 AY273897 BC034976 BG772379
RefSeq transcript (Entrez)NM_001289002 NM_001289004 NM_001308014 NM_173488
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLCO6A1
Cluster EST : UnigeneHs.388874 [ NCBI ]
CGAP (NCI)Hs.388874
Alternative Splicing GalleryENSG00000205359
Gene ExpressionSLCO6A1 [ NCBI-GEO ]   SLCO6A1 [ EBI - ARRAY_EXPRESS ]   SLCO6A1 [ SEEK ]   SLCO6A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLCO6A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)133482
GTEX Portal (Tissue expression)SLCO6A1
Human Protein AtlasENSG00000205359-SLCO6A1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UG4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UG4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UG4
Splice isoforms : SwissVarQ86UG4
PhosPhoSitePlusQ86UG4
Domaine pattern : Prosite (Expaxy)KAZAL_2 (PS51465)   
Domains : Interpro (EBI)Kazal_dom    Kazal_dom_sf    MFS_dom    MFS_trans_sf    OATP   
Domain families : Pfam (Sanger)Kazal_2 (PF07648)    OATP (PF03137)   
Domain families : Pfam (NCBI)pfam07648    pfam03137   
Conserved Domain (NCBI)SLCO6A1
DMDM Disease mutations133482
Blocks (Seattle)SLCO6A1
SuperfamilyQ86UG4
Human Protein Atlas [tissue]ENSG00000205359-SLCO6A1 [tissue]
Peptide AtlasQ86UG4
HPRD15400
IPIIPI00743263   IPI00328811   IPI00442213   IPI00953154   IPI00966547   
Protein Interaction databases
DIP (DOE-UCLA)Q86UG4
IntAct (EBI)Q86UG4
FunCoupENSG00000205359
BioGRIDSLCO6A1
STRING (EMBL)SLCO6A1
ZODIACSLCO6A1
Ontologies - Pathways
QuickGOQ86UG4
Ontology : AmiGOintegral component of plasma membrane  sodium-independent organic anion transmembrane transporter activity  sodium-independent organic anion transport  transmembrane transport  
Ontology : EGO-EBIintegral component of plasma membrane  sodium-independent organic anion transmembrane transporter activity  sodium-independent organic anion transport  transmembrane transport  
NDEx NetworkSLCO6A1
Atlas of Cancer Signalling NetworkSLCO6A1
Wikipedia pathwaysSLCO6A1
Orthology - Evolution
OrthoDB133482
GeneTree (enSembl)ENSG00000205359
Phylogenetic Trees/Animal Genes : TreeFamSLCO6A1
HOVERGENQ86UG4
HOGENOMQ86UG4
Homologs : HomoloGeneSLCO6A1
Homology/Alignments : Family Browser (UCSC)SLCO6A1
Gene fusions - Rearrangements
Fusion : MitelmanRAD51D/SLCO6A1 [17q12/5q21.1]  [t(5;17)(q21;q12)]  
Fusion PortalRAD51D 17q12 SLCO6A1 5q21.1 LUSC
Fusion : QuiverSLCO6A1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLCO6A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLCO6A1
dbVarSLCO6A1
ClinVarSLCO6A1
1000_GenomesSLCO6A1 
Exome Variant ServerSLCO6A1
ExAC (Exome Aggregation Consortium)ENSG00000205359
GNOMAD BrowserENSG00000205359
Varsome BrowserSLCO6A1
Genetic variants : HAPMAP133482
Genomic Variants (DGV)SLCO6A1 [DGVbeta]
DECIPHERSLCO6A1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLCO6A1 
Mutations
ICGC Data PortalSLCO6A1 
TCGA Data PortalSLCO6A1 
Broad Tumor PortalSLCO6A1
OASIS PortalSLCO6A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLCO6A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLCO6A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLCO6A1
DgiDB (Drug Gene Interaction Database)SLCO6A1
DoCM (Curated mutations)SLCO6A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLCO6A1 (select a term)
intoGenSLCO6A1
Cancer3DSLCO6A1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613365   
Orphanet
DisGeNETSLCO6A1
MedgenSLCO6A1
Genetic Testing Registry SLCO6A1
NextProtQ86UG4 [Medical]
TSGene133482
GENETestsSLCO6A1
Target ValidationSLCO6A1
Huge Navigator SLCO6A1 [HugePedia]
snp3D : Map Gene to Disease133482
BioCentury BCIQSLCO6A1
ClinGenSLCO6A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD133482
Chemical/Pharm GKB GenePA134949852
Clinical trialSLCO6A1
Miscellaneous
canSAR (ICR)SLCO6A1 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLCO6A1
EVEXSLCO6A1
GoPubMedSLCO6A1
iHOPSLCO6A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:40:22 CET 2018

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