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SLFN11 (schlafen family member 11)

Identity

Alias_symbol (synonym)FLJ34922
Other aliasSLFN8/9
HGNC (Hugo) SLFN11
LocusID (NCBI) 91607
Atlas_Id 53135
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 33677329 and ends at 33700720 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SLFN11 (17q12) / CPE (4q32.3)SLFN11 (17q12) / MIEN1 (17q12)SLFN11 17q12 C17orf37

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLFN11   26633
Cards
Entrez_Gene (NCBI)SLFN11  91607  schlafen family member 11
AliasesSLFN8/9
GeneCards (Weizmann)SLFN11
Ensembl hg19 (Hinxton)ENSG00000172716 [Gene_View]  chr17:33677329-33700720 [Contig_View]  SLFN11 [Vega]
Ensembl hg38 (Hinxton)ENSG00000172716 [Gene_View]  chr17:33677329-33700720 [Contig_View]  SLFN11 [Vega]
ICGC DataPortalENSG00000172716
TCGA cBioPortalSLFN11
AceView (NCBI)SLFN11
Genatlas (Paris)SLFN11
WikiGenes91607
SOURCE (Princeton)SLFN11
Genetics Home Reference (NIH)SLFN11
Genomic and cartography
GoldenPath hg19 (UCSC)SLFN11  -     chr17:33677329-33700720 -  17q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLFN11  -     17q12   [Description]    (hg38-Dec_2013)
EnsemblSLFN11 - 17q12 [CytoView hg19]  SLFN11 - 17q12 [CytoView hg38]
Mapping of homologs : NCBISLFN11 [Mapview hg19]  SLFN11 [Mapview hg38]
OMIM614953   
Gene and transcription
Genbank (Entrez)AK074184 AK092241 AL512731 AL831964 AM393675
RefSeq transcript (Entrez)NM_001104587 NM_001104588 NM_001104589 NM_001104590 NM_152270
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)SLFN11
Cluster EST : UnigeneHs.745059 [ NCBI ]
CGAP (NCI)Hs.745059
Alternative Splicing GalleryENSG00000172716
Gene ExpressionSLFN11 [ NCBI-GEO ]   SLFN11 [ EBI - ARRAY_EXPRESS ]   SLFN11 [ SEEK ]   SLFN11 [ MEM ]
Gene Expression Viewer (FireBrowse)SLFN11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)91607
GTEX Portal (Tissue expression)SLFN11
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z7L1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z7L1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z7L1
Splice isoforms : SwissVarQ7Z7L1
PhosPhoSitePlusQ7Z7L1
Domains : Interpro (EBI)DUF2075    P-loop_NTPase    Schlafen    Schlafen_AAA_dom    SLFN11   
Domain families : Pfam (Sanger)AlbA_2 (PF04326)    DUF2075 (PF09848)   
Domain families : Pfam (NCBI)pfam04326    pfam09848   
Conserved Domain (NCBI)SLFN11
DMDM Disease mutations91607
Blocks (Seattle)SLFN11
SuperfamilyQ7Z7L1
Human Protein AtlasENSG00000172716
Peptide AtlasQ7Z7L1
HPRD08178
IPIIPI00171044   IPI00790534   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z7L1
IntAct (EBI)Q7Z7L1
FunCoupENSG00000172716
BioGRIDSLFN11
STRING (EMBL)SLFN11
ZODIACSLFN11
Ontologies - Pathways
QuickGOQ7Z7L1
Ontology : AmiGOtRNA binding  ATP binding  nucleus  nucleoplasm  cytoplasm  aggresome  defense response to virus  negative regulation of G1/S transition of mitotic cell cycle  
Ontology : EGO-EBItRNA binding  ATP binding  nucleus  nucleoplasm  cytoplasm  aggresome  defense response to virus  negative regulation of G1/S transition of mitotic cell cycle  
NDEx NetworkSLFN11
Atlas of Cancer Signalling NetworkSLFN11
Wikipedia pathwaysSLFN11
Orthology - Evolution
OrthoDB91607
GeneTree (enSembl)ENSG00000172716
Phylogenetic Trees/Animal Genes : TreeFamSLFN11
HOVERGENQ7Z7L1
HOGENOMQ7Z7L1
Homologs : HomoloGeneSLFN11
Homology/Alignments : Family Browser (UCSC)SLFN11
Gene fusions - Rearrangements
Fusion: TCGASLFN11 17q12 C17orf37 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLFN11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLFN11
dbVarSLFN11
ClinVarSLFN11
1000_GenomesSLFN11 
Exome Variant ServerSLFN11
ExAC (Exome Aggregation Consortium)SLFN11 (select the gene name)
Genetic variants : HAPMAP91607
Genomic Variants (DGV)SLFN11 [DGVbeta]
DECIPHER (Syndromes)17:33677329-33700720  ENSG00000172716
CONAN: Copy Number AnalysisSLFN11 
Mutations
ICGC Data PortalSLFN11 
TCGA Data PortalSLFN11 
Broad Tumor PortalSLFN11
OASIS PortalSLFN11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLFN11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLFN11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLFN11
DgiDB (Drug Gene Interaction Database)SLFN11
DoCM (Curated mutations)SLFN11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLFN11 (select a term)
intoGenSLFN11
Cancer3DSLFN11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614953   
Orphanet
MedgenSLFN11
Genetic Testing Registry SLFN11
NextProtQ7Z7L1 [Medical]
TSGene91607
GENETestsSLFN11
Huge Navigator SLFN11 [HugePedia]
snp3D : Map Gene to Disease91607
BioCentury BCIQSLFN11
ClinGenSLFN11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD91607
Chemical/Pharm GKB GenePA144596358
Clinical trialSLFN11
Miscellaneous
canSAR (ICR)SLFN11 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLFN11
EVEXSLFN11
GoPubMedSLFN11
iHOPSLFN11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:28:09 CET 2017

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