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SLFN14 (schlafen family member 14)

Identity

Other aliasBDPLT20
HGNC (Hugo) SLFN14
LocusID (NCBI) 342618
Atlas_Id 73513
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 35548125 and ends at 35558091 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLFN14   32689
Cards
Entrez_Gene (NCBI)SLFN14  342618  schlafen family member 14
AliasesBDPLT20
GeneCards (Weizmann)SLFN14
Ensembl hg19 (Hinxton)ENSG00000236320 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000236320 [Gene_View]  chr17:35548125-35558091 [Contig_View]  SLFN14 [Vega]
ICGC DataPortalENSG00000236320
TCGA cBioPortalSLFN14
AceView (NCBI)SLFN14
Genatlas (Paris)SLFN14
WikiGenes342618
SOURCE (Princeton)SLFN14
Genetics Home Reference (NIH)SLFN14
Genomic and cartography
GoldenPath hg38 (UCSC)SLFN14  -     chr17:35548125-35558091 -  17q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLFN14  -     17q12   [Description]    (hg19-Feb_2009)
EnsemblSLFN14 - 17q12 [CytoView hg19]  SLFN14 - 17q12 [CytoView hg38]
Mapping of homologs : NCBISLFN14 [Mapview hg19]  SLFN14 [Mapview hg38]
OMIM614958   616913   
Gene and transcription
Genbank (Entrez)BC140847 BC157877 BC157879 BU658532
RefSeq transcript (Entrez)NM_001129820
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLFN14
Cluster EST : UnigeneHs.591193 [ NCBI ]
CGAP (NCI)Hs.591193
Alternative Splicing GalleryENSG00000236320
Gene ExpressionSLFN14 [ NCBI-GEO ]   SLFN14 [ EBI - ARRAY_EXPRESS ]   SLFN14 [ SEEK ]   SLFN14 [ MEM ]
Gene Expression Viewer (FireBrowse)SLFN14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)342618
GTEX Portal (Tissue expression)SLFN14
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0C7P3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0C7P3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0C7P3
Splice isoforms : SwissVarP0C7P3
PhosPhoSitePlusP0C7P3
Domains : Interpro (EBI)P-loop_NTPase    Schlafen    Schlafen_AAA_dom    SLFN14   
Domain families : Pfam (Sanger)AlbA_2 (PF04326)   
Domain families : Pfam (NCBI)pfam04326   
Conserved Domain (NCBI)SLFN14
DMDM Disease mutations342618
Blocks (Seattle)SLFN14
SuperfamilyP0C7P3
Human Protein AtlasENSG00000236320
Peptide AtlasP0C7P3
IPIIPI00477523   IPI00455330   
Protein Interaction databases
DIP (DOE-UCLA)P0C7P3
IntAct (EBI)P0C7P3
FunCoupENSG00000236320
BioGRIDSLFN14
STRING (EMBL)SLFN14
ZODIACSLFN14
Ontologies - Pathways
QuickGOP0C7P3
Ontology : AmiGOendoribonuclease activity  ATP binding  nucleus  cytoplasm  mRNA catabolic process  rRNA catabolic process  platelet maturation  ribosome binding  cellular response to magnesium ion  cellular response to manganese ion  RNA phosphodiester bond hydrolysis, endonucleolytic  
Ontology : EGO-EBIendoribonuclease activity  ATP binding  nucleus  cytoplasm  mRNA catabolic process  rRNA catabolic process  platelet maturation  ribosome binding  cellular response to magnesium ion  cellular response to manganese ion  RNA phosphodiester bond hydrolysis, endonucleolytic  
NDEx NetworkSLFN14
Atlas of Cancer Signalling NetworkSLFN14
Wikipedia pathwaysSLFN14
Orthology - Evolution
OrthoDB342618
GeneTree (enSembl)ENSG00000236320
Phylogenetic Trees/Animal Genes : TreeFamSLFN14
HOVERGENP0C7P3
HOGENOMP0C7P3
Homologs : HomoloGeneSLFN14
Homology/Alignments : Family Browser (UCSC)SLFN14
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLFN14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLFN14
dbVarSLFN14
ClinVarSLFN14
1000_GenomesSLFN14 
Exome Variant ServerSLFN14
ExAC (Exome Aggregation Consortium)SLFN14 (select the gene name)
Genetic variants : HAPMAP342618
Genomic Variants (DGV)SLFN14 [DGVbeta]
DECIPHERSLFN14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLFN14 
Mutations
ICGC Data PortalSLFN14 
TCGA Data PortalSLFN14 
Broad Tumor PortalSLFN14
OASIS PortalSLFN14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLFN14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLFN14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLFN14
DgiDB (Drug Gene Interaction Database)SLFN14
DoCM (Curated mutations)SLFN14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLFN14 (select a term)
intoGenSLFN14
Cancer3DSLFN14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614958    616913   
Orphanet
MedgenSLFN14
Genetic Testing Registry SLFN14
NextProtP0C7P3 [Medical]
TSGene342618
GENETestsSLFN14
Target ValidationSLFN14
Huge Navigator SLFN14 [HugePedia]
snp3D : Map Gene to Disease342618
BioCentury BCIQSLFN14
ClinGenSLFN14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD342618
Chemical/Pharm GKB GenePA144596361
Clinical trialSLFN14
Miscellaneous
canSAR (ICR)SLFN14 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLFN14
EVEXSLFN14
GoPubMedSLFN14
iHOPSLFN14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:38:22 CEST 2017

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