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SLITRK1 (SLIT and NTRK like family member 1)

Identity

Alias_namesLRRC12
leucine rich repeat containing 12
SLIT and NTRK-like family, member 1
Alias_symbol (synonym)KIAA1910
Other aliasTTM
HGNC (Hugo) SLITRK1
LocusID (NCBI) 114798
Atlas_Id 73519
Location 13q31.1  [Link to chromosome band 13q31]
Location_base_pair Starts at 83877205 and ends at 83882393 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLITRK1   20297
Cards
Entrez_Gene (NCBI)SLITRK1  114798  SLIT and NTRK like family member 1
AliasesLRRC12; TTM
GeneCards (Weizmann)SLITRK1
Ensembl hg19 (Hinxton)ENSG00000178235 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178235 [Gene_View]  chr13:83877205-83882393 [Contig_View]  SLITRK1 [Vega]
ICGC DataPortalENSG00000178235
TCGA cBioPortalSLITRK1
AceView (NCBI)SLITRK1
Genatlas (Paris)SLITRK1
WikiGenes114798
SOURCE (Princeton)SLITRK1
Genetics Home Reference (NIH)SLITRK1
Genomic and cartography
GoldenPath hg38 (UCSC)SLITRK1  -     chr13:83877205-83882393 -  13q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLITRK1  -     13q31.1   [Description]    (hg19-Feb_2009)
EnsemblSLITRK1 - 13q31.1 [CytoView hg19]  SLITRK1 - 13q31.1 [CytoView hg38]
Mapping of homologs : NCBISLITRK1 [Mapview hg19]  SLITRK1 [Mapview hg38]
OMIM137580   609678   613229   
Gene and transcription
Genbank (Entrez)AA677641 AB067497 AI500170 AK299479 AY358289
RefSeq transcript (Entrez)NM_001281503 NM_052910
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLITRK1
Cluster EST : UnigeneHs.694617 [ NCBI ]
CGAP (NCI)Hs.694617
Alternative Splicing GalleryENSG00000178235
Gene ExpressionSLITRK1 [ NCBI-GEO ]   SLITRK1 [ EBI - ARRAY_EXPRESS ]   SLITRK1 [ SEEK ]   SLITRK1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLITRK1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114798
GTEX Portal (Tissue expression)SLITRK1
Human Protein AtlasENSG00000178235-SLITRK1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PX8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PX8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PX8
Splice isoforms : SwissVarQ96PX8
PhosPhoSitePlusQ96PX8
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  
Conserved Domain (NCBI)SLITRK1
DMDM Disease mutations114798
Blocks (Seattle)SLITRK1
PDB (SRS)4RCA    4RCW   
PDB (PDBSum)4RCA    4RCW   
PDB (IMB)4RCA    4RCW   
PDB (RSDB)4RCA    4RCW   
Structural Biology KnowledgeBase4RCA    4RCW   
SCOP (Structural Classification of Proteins)4RCA    4RCW   
CATH (Classification of proteins structures)4RCA    4RCW   
SuperfamilyQ96PX8
Human Protein Atlas [tissue]ENSG00000178235-SLITRK1 [tissue]
Peptide AtlasQ96PX8
HPRD18063
IPIIPI00102543   
Protein Interaction databases
DIP (DOE-UCLA)Q96PX8
IntAct (EBI)Q96PX8
FunCoupENSG00000178235
BioGRIDSLITRK1
STRING (EMBL)SLITRK1
ZODIACSLITRK1
Ontologies - Pathways
QuickGOQ96PX8
Ontology : AmiGOprotein binding  extracellular region  axonogenesis  synapse assembly  integral component of membrane  cell junction  adult behavior  multicellular organism growth  homeostatic process  synapse  positive regulation of axonogenesis  positive regulation of synapse assembly  
Ontology : EGO-EBIprotein binding  extracellular region  axonogenesis  synapse assembly  integral component of membrane  cell junction  adult behavior  multicellular organism growth  homeostatic process  synapse  positive regulation of axonogenesis  positive regulation of synapse assembly  
NDEx NetworkSLITRK1
Atlas of Cancer Signalling NetworkSLITRK1
Wikipedia pathwaysSLITRK1
Orthology - Evolution
OrthoDB114798
GeneTree (enSembl)ENSG00000178235
Phylogenetic Trees/Animal Genes : TreeFamSLITRK1
HOVERGENQ96PX8
HOGENOMQ96PX8
Homologs : HomoloGeneSLITRK1
Homology/Alignments : Family Browser (UCSC)SLITRK1
Gene fusions - Rearrangements
Tumor Fusion PortalSLITRK1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLITRK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLITRK1
dbVarSLITRK1
ClinVarSLITRK1
1000_GenomesSLITRK1 
Exome Variant ServerSLITRK1
ExAC (Exome Aggregation Consortium)ENSG00000178235
GNOMAD BrowserENSG00000178235
Genetic variants : HAPMAP114798
Genomic Variants (DGV)SLITRK1 [DGVbeta]
DECIPHERSLITRK1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLITRK1 
Mutations
ICGC Data PortalSLITRK1 
TCGA Data PortalSLITRK1 
Broad Tumor PortalSLITRK1
OASIS PortalSLITRK1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLITRK1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLITRK1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLITRK1
DgiDB (Drug Gene Interaction Database)SLITRK1
DoCM (Curated mutations)SLITRK1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLITRK1 (select a term)
intoGenSLITRK1
Cancer3DSLITRK1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137580    609678    613229   
Orphanet
DisGeNETSLITRK1
MedgenSLITRK1
Genetic Testing Registry SLITRK1
NextProtQ96PX8 [Medical]
TSGene114798
GENETestsSLITRK1
Target ValidationSLITRK1
Huge Navigator SLITRK1 [HugePedia]
snp3D : Map Gene to Disease114798
BioCentury BCIQSLITRK1
ClinGenSLITRK1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114798
Chemical/Pharm GKB GenePA134944423
Clinical trialSLITRK1
Miscellaneous
canSAR (ICR)SLITRK1 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLITRK1
EVEXSLITRK1
GoPubMedSLITRK1
iHOPSLITRK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:28:57 CET 2017

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