Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SLITRK1 (SLIT and NTRK like family member 1)

Identity

Alias (NCBI)LRRC12
TTM
HGNC (Hugo) SLITRK1
HGNC Alias symbKIAA1910
HGNC Previous nameLRRC12
HGNC Previous nameleucine rich repeat containing 12
 SLIT and NTRK-like family, member 1
LocusID (NCBI) 114798
Atlas_Id 73519
Location 13q31.1  [Link to chromosome band 13q31]
Location_base_pair Starts at 83877205 and ends at 83882393 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SLITRK1   20297
Cards
Entrez_Gene (NCBI)SLITRK1    SLIT and NTRK like family member 1
AliasesLRRC12; TTM
GeneCards (Weizmann)SLITRK1
Ensembl hg19 (Hinxton)ENSG00000178235 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178235 [Gene_View]  ENSG00000178235 [Sequence]  chr13:83877205-83882393 [Contig_View]  SLITRK1 [Vega]
ICGC DataPortalENSG00000178235
TCGA cBioPortalSLITRK1
AceView (NCBI)SLITRK1
Genatlas (Paris)SLITRK1
SOURCE (Princeton)SLITRK1
Genetics Home Reference (NIH)SLITRK1
Genomic and cartography
GoldenPath hg38 (UCSC)SLITRK1  -     chr13:83877205-83882393 -  13q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLITRK1  -     13q31.1   [Description]    (hg19-Feb_2009)
GoldenPathSLITRK1 - 13q31.1 [CytoView hg19]  SLITRK1 - 13q31.1 [CytoView hg38]
ImmunoBaseENSG00000178235
Genome Data Viewer NCBISLITRK1 [Mapview hg19]  
OMIM137580   609678   613229   
Gene and transcription
Genbank (Entrez)AA677641 AB067497 AI500170 AK299479 AY358289
RefSeq transcript (Entrez)NM_001281503 NM_052910
Consensus coding sequences : CCDS (NCBI)SLITRK1
Gene ExpressionSLITRK1 [ NCBI-GEO ]   SLITRK1 [ EBI - ARRAY_EXPRESS ]   SLITRK1 [ SEEK ]   SLITRK1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLITRK1 [ Firebrowse - Broad ]
GenevisibleExpression of SLITRK1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114798
GTEX Portal (Tissue expression)SLITRK1
Human Protein AtlasENSG00000178235-SLITRK1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PX8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PX8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PX8
PhosPhoSitePlusQ96PX8
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf    Slitrk   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  
Conserved Domain (NCBI)SLITRK1
PDB (RSDB)4RCA    4RCW   
PDB Europe4RCA    4RCW   
PDB (PDBSum)4RCA    4RCW   
PDB (IMB)4RCA    4RCW   
Structural Biology KnowledgeBase4RCA    4RCW   
SCOP (Structural Classification of Proteins)4RCA    4RCW   
CATH (Classification of proteins structures)4RCA    4RCW   
SuperfamilyQ96PX8
AlphaFold pdb e-kbQ96PX8   
Human Protein Atlas [tissue]ENSG00000178235-SLITRK1 [tissue]
HPRD18063
Protein Interaction databases
DIP (DOE-UCLA)Q96PX8
IntAct (EBI)Q96PX8
BioGRIDSLITRK1
STRING (EMBL)SLITRK1
ZODIACSLITRK1
Ontologies - Pathways
QuickGOQ96PX8
Ontology : AmiGOprotein binding  extracellular region  plasma membrane  axonogenesis  synapse assembly  adult behavior  multicellular organism growth  homeostatic process  synapse  positive regulation of axonogenesis  positive regulation of synapse assembly  glutamatergic synapse  glutamatergic synapse  GABA-ergic synapse  GABA-ergic synapse  integral component of postsynaptic density membrane  synaptic membrane adhesion  synaptic membrane adhesion  regulation of presynapse assembly  regulation of presynapse assembly  
Ontology : EGO-EBIprotein binding  extracellular region  plasma membrane  axonogenesis  synapse assembly  adult behavior  multicellular organism growth  homeostatic process  synapse  positive regulation of axonogenesis  positive regulation of synapse assembly  glutamatergic synapse  glutamatergic synapse  GABA-ergic synapse  GABA-ergic synapse  integral component of postsynaptic density membrane  synaptic membrane adhesion  synaptic membrane adhesion  regulation of presynapse assembly  regulation of presynapse assembly  
NDEx NetworkSLITRK1
Atlas of Cancer Signalling NetworkSLITRK1
Wikipedia pathwaysSLITRK1
Orthology - Evolution
OrthoDB114798
GeneTree (enSembl)ENSG00000178235
Phylogenetic Trees/Animal Genes : TreeFamSLITRK1
Homologs : HomoloGeneSLITRK1
Homology/Alignments : Family Browser (UCSC)SLITRK1
Gene fusions - Rearrangements
Fusion : QuiverSLITRK1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLITRK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLITRK1
dbVarSLITRK1
ClinVarSLITRK1
MonarchSLITRK1
1000_GenomesSLITRK1 
Exome Variant ServerSLITRK1
GNOMAD BrowserENSG00000178235
Varsome BrowserSLITRK1
ACMGSLITRK1 variants
VarityQ96PX8
Genomic Variants (DGV)SLITRK1 [DGVbeta]
DECIPHERSLITRK1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLITRK1 
Mutations
ICGC Data PortalSLITRK1 
TCGA Data PortalSLITRK1 
Broad Tumor PortalSLITRK1
OASIS PortalSLITRK1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLITRK1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLITRK1
Mutations and Diseases : HGMDSLITRK1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSLITRK1
DgiDB (Drug Gene Interaction Database)SLITRK1
DoCM (Curated mutations)SLITRK1
CIViC (Clinical Interpretations of Variants in Cancer)SLITRK1
Cancer3DSLITRK1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM137580    609678    613229   
Orphanet
DisGeNETSLITRK1
MedgenSLITRK1
Genetic Testing Registry SLITRK1
NextProtQ96PX8 [Medical]
GENETestsSLITRK1
Target ValidationSLITRK1
Huge Navigator SLITRK1 [HugePedia]
ClinGenSLITRK1
Clinical trials, drugs, therapy
MyCancerGenomeSLITRK1
Protein Interactions : CTDSLITRK1
Pharm GKB GenePA134944423
PharosQ96PX8
Clinical trialSLITRK1
Miscellaneous
canSAR (ICR)SLITRK1
HarmonizomeSLITRK1
DataMed IndexSLITRK1
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSLITRK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:21:18 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.