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SLITRK4 (SLIT and NTRK like family member 4)

Identity

Alias (NCBI)-
HGNC (Hugo) SLITRK4
HGNC Alias symbDKFZp547M2010
HGNC Previous nameSLIT and NTRK-like family, member 4
LocusID (NCBI) 139065
Atlas_Id 73522
Location Xq27.3  [Link to chromosome band Xq27]
Location_base_pair Starts at 143622790 and ends at 143635091 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KMT5B (11q13.2)::SLITRK4 (Xq27.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SLITRK4   23502
Cards
Entrez_Gene (NCBI)SLITRK4    SLIT and NTRK like family member 4
Aliases
GeneCards (Weizmann)SLITRK4
Ensembl hg19 (Hinxton)ENSG00000179542 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179542 [Gene_View]  ENSG00000179542 [Sequence]  chrX:143622790-143635091 [Contig_View]  SLITRK4 [Vega]
ICGC DataPortalENSG00000179542
TCGA cBioPortalSLITRK4
AceView (NCBI)SLITRK4
Genatlas (Paris)SLITRK4
SOURCE (Princeton)SLITRK4
Genetics Home Reference (NIH)SLITRK4
Genomic and cartography
GoldenPath hg38 (UCSC)SLITRK4  -     chrX:143622790-143635091 -  Xq27.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLITRK4  -     Xq27.3   [Description]    (hg19-Feb_2009)
GoldenPathSLITRK4 - Xq27.3 [CytoView hg19]  SLITRK4 - Xq27.3 [CytoView hg38]
ImmunoBaseENSG00000179542
Genome Data Viewer NCBISLITRK4 [Mapview hg19]  
OMIM300562   
Gene and transcription
Genbank (Entrez)AI286228 AK057619 AK092016 AK315044 AL713693
RefSeq transcript (Entrez)NM_001184749 NM_001184750 NM_173078
Consensus coding sequences : CCDS (NCBI)SLITRK4
Gene ExpressionSLITRK4 [ NCBI-GEO ]   SLITRK4 [ EBI - ARRAY_EXPRESS ]   SLITRK4 [ SEEK ]   SLITRK4 [ MEM ]
Gene Expression Viewer (FireBrowse)SLITRK4 [ Firebrowse - Broad ]
GenevisibleExpression of SLITRK4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)139065
GTEX Portal (Tissue expression)SLITRK4
Human Protein AtlasENSG00000179542-SLITRK4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IW52   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IW52  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IW52
PhosPhoSitePlusQ8IW52
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf    Slitrk   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  
Conserved Domain (NCBI)SLITRK4
SuperfamilyQ8IW52
AlphaFold pdb e-kbQ8IW52   
Human Protein Atlas [tissue]ENSG00000179542-SLITRK4 [tissue]
HPRD06486
Protein Interaction databases
DIP (DOE-UCLA)Q8IW52
IntAct (EBI)Q8IW52
BioGRIDSLITRK4
STRING (EMBL)SLITRK4
ZODIACSLITRK4
Ontologies - Pathways
QuickGOQ8IW52
Ontology : AmiGOplasma membrane  axonogenesis  integral component of membrane  regulation of synapse organization  regulation of synapse organization  positive regulation of synapse assembly  glutamatergic synapse  glutamatergic synapse  regulation of presynapse assembly  
Ontology : EGO-EBIplasma membrane  axonogenesis  integral component of membrane  regulation of synapse organization  regulation of synapse organization  positive regulation of synapse assembly  glutamatergic synapse  glutamatergic synapse  regulation of presynapse assembly  
NDEx NetworkSLITRK4
Atlas of Cancer Signalling NetworkSLITRK4
Wikipedia pathwaysSLITRK4
Orthology - Evolution
OrthoDB139065
GeneTree (enSembl)ENSG00000179542
Phylogenetic Trees/Animal Genes : TreeFamSLITRK4
Homologs : HomoloGeneSLITRK4
Homology/Alignments : Family Browser (UCSC)SLITRK4
Gene fusions - Rearrangements
Fusion : QuiverSLITRK4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLITRK4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLITRK4
dbVarSLITRK4
ClinVarSLITRK4
MonarchSLITRK4
1000_GenomesSLITRK4 
Exome Variant ServerSLITRK4
GNOMAD BrowserENSG00000179542
Varsome BrowserSLITRK4
ACMGSLITRK4 variants
VarityQ8IW52
Genomic Variants (DGV)SLITRK4 [DGVbeta]
DECIPHERSLITRK4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLITRK4 
Mutations
ICGC Data PortalSLITRK4 
TCGA Data PortalSLITRK4 
Broad Tumor PortalSLITRK4
OASIS PortalSLITRK4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLITRK4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLITRK4
Mutations and Diseases : HGMDSLITRK4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSLITRK4
DgiDB (Drug Gene Interaction Database)SLITRK4
DoCM (Curated mutations)SLITRK4
CIViC (Clinical Interpretations of Variants in Cancer)SLITRK4
Cancer3DSLITRK4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300562   
Orphanet
DisGeNETSLITRK4
MedgenSLITRK4
Genetic Testing Registry SLITRK4
NextProtQ8IW52 [Medical]
GENETestsSLITRK4
Target ValidationSLITRK4
Huge Navigator SLITRK4 [HugePedia]
ClinGenSLITRK4
Clinical trials, drugs, therapy
MyCancerGenomeSLITRK4
Protein Interactions : CTDSLITRK4
Pharm GKB GenePA134926932
PharosQ8IW52
Clinical trialSLITRK4
Miscellaneous
canSAR (ICR)SLITRK4
HarmonizomeSLITRK4
ARCHS4SLITRK4
DataMed IndexSLITRK4
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSLITRK4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jan 20 13:51:06 CET 2022

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