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SLN (sarcolipin)

Identity

Alias (NCBI)-
HGNC (Hugo) SLN
HGNC Alias symbMGC12301
MGC125854
MGC125855
LocusID (NCBI) 6588
Atlas_Id 73529
Location 11q22.3  [Link to chromosome band 11q22]
Location_base_pair Starts at 107707381 and ends at 107712056 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLN (11q22.3) / CADM2 (3p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SLN   11089
Cards
Entrez_Gene (NCBI)SLN    sarcolipin
Aliases
GeneCards (Weizmann)SLN
Ensembl hg19 (Hinxton)ENSG00000170290 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170290 [Gene_View]  ENSG00000170290 [Sequence]  chr11:107707381-107712056 [Contig_View]  SLN [Vega]
ICGC DataPortalENSG00000170290
TCGA cBioPortalSLN
AceView (NCBI)SLN
Genatlas (Paris)SLN
SOURCE (Princeton)SLN
Genetics Home Reference (NIH)SLN
Genomic and cartography
GoldenPath hg38 (UCSC)SLN  -     chr11:107707381-107712056 -  11q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLN  -     11q22.3   [Description]    (hg19-Feb_2009)
GoldenPathSLN - 11q22.3 [CytoView hg19]  SLN - 11q22.3 [CytoView hg38]
ImmunoBaseENSG00000170290
Genome Data Viewer NCBISLN [Mapview hg19]  
OMIM602203   
Gene and transcription
Genbank (Entrez)AK312097 BC005261 BC094685 BC104150 BC104185
RefSeq transcript (Entrez)NM_003063
Consensus coding sequences : CCDS (NCBI)SLN
Gene ExpressionSLN [ NCBI-GEO ]   SLN [ EBI - ARRAY_EXPRESS ]   SLN [ SEEK ]   SLN [ MEM ]
Gene Expression Viewer (FireBrowse)SLN [ Firebrowse - Broad ]
GenevisibleExpression of SLN in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6588
GTEX Portal (Tissue expression)SLN
Human Protein AtlasENSG00000170290-SLN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00631   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00631  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00631
PhosPhoSitePlusO00631
Domains : Interpro (EBI)Sarcolipin   
Domain families : Pfam (Sanger)Sarcolipin (PF05366)   
Domain families : Pfam (NCBI)pfam05366   
Conserved Domain (NCBI)SLN
PDB (RSDB)1JDM   
PDB Europe1JDM   
PDB (PDBSum)1JDM   
PDB (IMB)1JDM   
Structural Biology KnowledgeBase1JDM   
SCOP (Structural Classification of Proteins)1JDM   
CATH (Classification of proteins structures)1JDM   
SuperfamilyO00631
AlphaFold pdb e-kbO00631   
Human Protein Atlas [tissue]ENSG00000170290-SLN [tissue]
HPRD03729
Protein Interaction databases
DIP (DOE-UCLA)O00631
IntAct (EBI)O00631
BioGRIDSLN
STRING (EMBL)SLN
ZODIACSLN
Ontologies - Pathways
QuickGOO00631
Ontology : AmiGOenzyme inhibitor activity  protein binding  calcium ion transport  integral component of membrane  sarcoplasmic reticulum  enzyme regulator activity  sarcoplasmic reticulum membrane  negative regulation of catalytic activity  negative regulation of protein-containing complex disassembly  ATPase binding  regulation of calcium ion transport  sarcoplasmic reticulum calcium ion transport  negative regulation of calcium ion import  positive regulation of cold-induced thermogenesis  negative regulation of calcium ion transmembrane transporter activity  regulation of relaxation of muscle  negative regulation of calcium ion binding  positive regulation of protein depolymerization  regulation of ATPase-coupled calcium transmembrane transporter activity  negative regulation of ATPase-coupled calcium transmembrane transporter activity  
Ontology : EGO-EBIenzyme inhibitor activity  protein binding  calcium ion transport  integral component of membrane  sarcoplasmic reticulum  enzyme regulator activity  sarcoplasmic reticulum membrane  negative regulation of catalytic activity  negative regulation of protein-containing complex disassembly  ATPase binding  regulation of calcium ion transport  sarcoplasmic reticulum calcium ion transport  negative regulation of calcium ion import  positive regulation of cold-induced thermogenesis  negative regulation of calcium ion transmembrane transporter activity  regulation of relaxation of muscle  negative regulation of calcium ion binding  positive regulation of protein depolymerization  regulation of ATPase-coupled calcium transmembrane transporter activity  negative regulation of ATPase-coupled calcium transmembrane transporter activity  
NDEx NetworkSLN
Atlas of Cancer Signalling NetworkSLN
Wikipedia pathwaysSLN
Orthology - Evolution
OrthoDB6588
GeneTree (enSembl)ENSG00000170290
Phylogenetic Trees/Animal Genes : TreeFamSLN
Homologs : HomoloGeneSLN
Homology/Alignments : Family Browser (UCSC)SLN
Gene fusions - Rearrangements
Fusion : QuiverSLN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLN
dbVarSLN
ClinVarSLN
MonarchSLN
1000_GenomesSLN 
Exome Variant ServerSLN
GNOMAD BrowserENSG00000170290
Varsome BrowserSLN
ACMGSLN variants
VarityO00631
Genomic Variants (DGV)SLN [DGVbeta]
DECIPHERSLN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLN 
Mutations
ICGC Data PortalSLN 
TCGA Data PortalSLN 
Broad Tumor PortalSLN
OASIS PortalSLN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLN  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLN
Mutations and Diseases : HGMDSLN
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSLN
DgiDB (Drug Gene Interaction Database)SLN
DoCM (Curated mutations)SLN
CIViC (Clinical Interpretations of Variants in Cancer)SLN
Cancer3DSLN
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602203   
Orphanet
DisGeNETSLN
MedgenSLN
Genetic Testing Registry SLN
NextProtO00631 [Medical]
GENETestsSLN
Target ValidationSLN
Huge Navigator SLN [HugePedia]
ClinGenSLN
Clinical trials, drugs, therapy
MyCancerGenomeSLN
Protein Interactions : CTDSLN
Pharm GKB GenePA35942
PharosO00631
Clinical trialSLN
Miscellaneous
canSAR (ICR)SLN
HarmonizomeSLN
DataMed IndexSLN
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSLN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:21:19 CEST 2021

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