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SLPI (secretory leukocyte peptidase inhibitor)

Identity

Other namesALK1
ALP
BLPI
HUSI
HUSI-I
MPI
WAP4
WFDC4
HGNC (Hugo) SLPI
LocusID (NCBI) 6590
Location 20q13.12
Location_base_pair Starts at 43880879 and ends at 43883206 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SLPI   11092
Entrez_Gene (NCBI)SLPI  6590  secretory leukocyte peptidase inhibitor
Cards
GeneCards (Weizmann)SLPI
Ensembl (Hinxton)ENSG00000124107 [Gene_View]  chr20:43880879-43883206 [Contig_View]  SLPI [Vega]
AceView (NCBI)SLPI
Genatlas (Paris)SLPI
SOURCE (Stanford)NM_003064
Genomic and cartography
GoldenPath (UCSC)SLPI  -  20q13.12   chr20:43880879-43883206 -  20q13.12   [Description]    (hg19-Feb_2009)
EnsemblSLPI - 20q13.12 [CytoView]
Mapping of homologs : NCBISLPI [Mapview]
OMIM107285   
Gene and transcription
Genbank (Entrez)AF114471 AK312192 AX772818 BC020708 DQ891365
RefSeq transcript (SRS)NM_003064
RefSeq transcript (Entrez)NM_003064
RefSeq genomic (SRS)AC_000152 NC_000020 NC_018931 NG_028137 NT_011362 NW_001838666 NW_004078102
RefSeq genomic (Entrez)AC_000152 NC_000020 NC_018931 NG_028137 NT_011362 NW_001838666 NW_004078102
Consensus coding sequences : CCDS (NCBI)SLPI
Cluster EST : UnigeneHs.517070 [ SRS ] Hs.517070 [ NCBI ]
CGAP (NCI)Hs.517070
Alternative Splicing : Fast-db (Paris)GSHG0019203
Alternative Splicing GalleryENSG00000124107
Gene ExpressionSLPI [ NCBI-GEO ]   SLPI [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP03973 (SRS) P03973 (Uniprot)
NextProtP03973
With graphics : InterProP03973
Splice isoforms : SwissVarP03973(Swissvar)
Domaine pattern : Prosite (SRS)WAP (PS51390)   
Domaine pattern : Prosite (Expaxy)WAP (PS51390)   
Domains : Interpro (SRS)4-disulphide_core    Whey_acidic_protein_4-diS_core   
Domains : Interpro (EBI)4-disulphide_core    Whey_acidic_protein_4-diS_core   
Related proteins : CluSTrP03973
Domain families : Pfam (SRS)WAP (PF00095)   
Domain families : Pfam (Sanger)WAP (PF00095)   
Domain families : Pfam (NCBI)pfam00095   
Domain families : Smart (EMBL)WAP (SM00217)  
DMDM6590
Blocks (Seattle)P03973
PDB (SRS)2Z7F   
PDB (PDBSum)2Z7F   
PDB (IMB)2Z7F   
PDB (RSDB)2Z7F   
Human Protein AtlasENSG00000124107
HPRD00121
IPIIPI00008580   
Protein Interaction databases
DIP (DOE-UCLA)P03973
IntAct (EBI)P03973
FunCoupENSG00000124107
REACTOMESLPI
Protein Interaction Database6590
BioGRIDSLPI
InParanoidP03973
Interologous Interaction database P03973
IntegromeDBSLPI
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SLPI
SNP (GeneSNP Utah)SLPI
SNP : HGBaseSLPI
Genetic variants : HAPMAPSLPI
Somatic Mutations in Cancer : COSMICSLPI 
CONAN: Copy Number AnalysisSLPI 
Mutations and Diseases : HGMDSLPI
OMIM107285   
GENETests107285   
Disease Genetic AssociationSLPI
Huge Navigator SLPI [HugePedia]  SLPI [HugeCancerGEM]
Genomic VariantsSLPI  SLPI [DGVbeta]
snp3D : Map Gene to Disease6590
General knowledge
Homologs : HomoloGeneSLPI
Homology/Alignments : Family Browser (UCSC)SLPI
Phylogenetic Trees/Animal Genes : TreeFamSLPI
Chemical/Protein Interactions : CTD6590
Chemical/Pharm GKB GenePA35944
Clinical trialSLPI
Cancer Resource (Charite)ENSG00000124107
Ontology : AmiGOendopeptidase inhibitor activity  serine-type endopeptidase inhibitor activity  protein binding  extracellular region  negative regulation of endopeptidase activity  enzyme binding  extracellular matrix  negative regulation of protein binding  negative regulation of viral genome replication  
Ontology : EGO-EBIendopeptidase inhibitor activity  serine-type endopeptidase inhibitor activity  protein binding  extracellular region  negative regulation of endopeptidase activity  enzyme binding  extracellular matrix  negative regulation of protein binding  negative regulation of viral genome replication  
Pathways : BIOCARTAProepithelin Conversion to Epithelin and Wound Repair Control [Genes]   
Other databases
Probes
Litterature
PubMed94 Pubmed reference(s) in Entrez
PubGeneSLPI
iHOPSLPI
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:36:21 CEST 2013
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