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SLTM (SAFB like transcription modulator)

Identity

Alias_symbol (synonym)Met
FLJ13213
Other alias
HGNC (Hugo) SLTM
LocusID (NCBI) 79811
Atlas_Id 53047
Location 15q22.1  [Link to chromosome band 15q22]
Location_base_pair Starts at 58879045 and ends at 58933676 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BST1 (4p15.32) / SLTM (15q22.1)C14orf2 (14q32.33) / SLTM (15q22.1)CLTC (17q23.1) / SLTM (15q22.1)
IGFBP7 (4q12) / SLTM (15q22.1)PNN (14q21.1) / SLTM (15q22.1)SLTM (15q22.1) / ADM (11p15.4)
SLTM (15q22.1) / ATE1 (10q26.13)SLTM (15q22.1) / C6orf89 (6p21.2)SLTM (15q22.1) / CLTC (17q23.1)
SLTM (15q22.1) / IGFBP7 (4q12)SLTM (15q22.1) / SLTM (15q22.1)SLTM (15q22.1) / UACA (15q23)
SPATS2 (12q13.12) / SLTM (15q22.1)TAB2 (6q25.1) / SLTM (15q22.1)USP5 (12p13.31) / SLTM (15q22.1)
SLTM 15q22.1 / ATE1 10q26.13SLTM 15q22.1 / UACA 15q23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(10;15)(q26;q22) SLTM/ATE1
t(15;15)(q22;q23) SLTM/UACA


External links

Nomenclature
HGNC (Hugo)SLTM   20709
Cards
Entrez_Gene (NCBI)SLTM  79811  SAFB like transcription modulator
AliasesMet
GeneCards (Weizmann)SLTM
Ensembl hg19 (Hinxton)ENSG00000137776 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137776 [Gene_View]  ENSG00000137776 [Sequence]  chr15:58879045-58933676 [Contig_View]  SLTM [Vega]
ICGC DataPortalENSG00000137776
TCGA cBioPortalSLTM
AceView (NCBI)SLTM
Genatlas (Paris)SLTM
WikiGenes79811
SOURCE (Princeton)SLTM
Genetics Home Reference (NIH)SLTM
Genomic and cartography
GoldenPath hg38 (UCSC)SLTM  -     chr15:58879045-58933676 -  15q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLTM  -     15q22.1   [Description]    (hg19-Feb_2009)
EnsemblSLTM - 15q22.1 [CytoView hg19]  SLTM - 15q22.1 [CytoView hg38]
Mapping of homologs : NCBISLTM [Mapview hg19]  SLTM [Mapview hg38]
Gene and transcription
Genbank (Entrez)AI215187 AI745094 AK000867 AK023275 AK024710
RefSeq transcript (Entrez)NM_001013843 NM_017968 NM_024755
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLTM
Cluster EST : UnigeneHs.512932 [ NCBI ]
CGAP (NCI)Hs.512932
Alternative Splicing GalleryENSG00000137776
Gene ExpressionSLTM [ NCBI-GEO ]   SLTM [ EBI - ARRAY_EXPRESS ]   SLTM [ SEEK ]   SLTM [ MEM ]
Gene Expression Viewer (FireBrowse)SLTM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79811
GTEX Portal (Tissue expression)SLTM
Human Protein AtlasENSG00000137776-SLTM [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NWH9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NWH9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NWH9
Splice isoforms : SwissVarQ9NWH9
PhosPhoSitePlusQ9NWH9
Domaine pattern : Prosite (Expaxy)RRM (PS50102)    SAP (PS50800)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait_sf    RBD_domain_sf    RRM_dom    SAP_dom    SAP_dom_sf    SLTM   
Domain families : Pfam (Sanger)RRM_1 (PF00076)    SAP (PF02037)   
Domain families : Pfam (NCBI)pfam00076    pfam02037   
Domain families : Smart (EMBL)RRM (SM00360)  SAP (SM00513)  
Conserved Domain (NCBI)SLTM
DMDM Disease mutations79811
Blocks (Seattle)SLTM
SuperfamilyQ9NWH9
Human Protein Atlas [tissue]ENSG00000137776-SLTM [tissue]
Peptide AtlasQ9NWH9
HPRD07819
IPIIPI00792743   IPI00019996   IPI00791423   
Protein Interaction databases
DIP (DOE-UCLA)Q9NWH9
IntAct (EBI)Q9NWH9
FunCoupENSG00000137776
BioGRIDSLTM
STRING (EMBL)SLTM
ZODIACSLTM
Ontologies - Pathways
QuickGOQ9NWH9
Ontology : AmiGORNA binding  nucleus  nucleoplasm  transcription, DNA-templated  regulation of transcription by RNA polymerase II  apoptotic process  nuclear body  sequence-specific DNA binding  regulation of mRNA processing  
Ontology : EGO-EBIRNA binding  nucleus  nucleoplasm  transcription, DNA-templated  regulation of transcription by RNA polymerase II  apoptotic process  nuclear body  sequence-specific DNA binding  regulation of mRNA processing  
NDEx NetworkSLTM
Atlas of Cancer Signalling NetworkSLTM
Wikipedia pathwaysSLTM
Orthology - Evolution
OrthoDB79811
GeneTree (enSembl)ENSG00000137776
Phylogenetic Trees/Animal Genes : TreeFamSLTM
HOVERGENQ9NWH9
HOGENOMQ9NWH9
Homologs : HomoloGeneSLTM
Homology/Alignments : Family Browser (UCSC)SLTM
Gene fusions - Rearrangements
Fusion : MitelmanSLTM/ATE1 [15q22.1/10q26.13]  
Fusion : MitelmanSLTM/UACA [15q22.1/15q23]  [t(15;15)(q22;q23)]  
Fusion PortalSLTM 15q22.1 ATE1 10q26.13 BRCA
Fusion PortalSLTM 15q22.1 UACA 15q23 BRCA
Fusion : QuiverSLTM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLTM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLTM
dbVarSLTM
ClinVarSLTM
1000_GenomesSLTM 
Exome Variant ServerSLTM
ExAC (Exome Aggregation Consortium)ENSG00000137776
GNOMAD BrowserENSG00000137776
Varsome BrowserSLTM
Genetic variants : HAPMAP79811
Genomic Variants (DGV)SLTM [DGVbeta]
DECIPHERSLTM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLTM 
Mutations
ICGC Data PortalSLTM 
TCGA Data PortalSLTM 
Broad Tumor PortalSLTM
OASIS PortalSLTM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLTM  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLTM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLTM
DgiDB (Drug Gene Interaction Database)SLTM
DoCM (Curated mutations)SLTM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLTM (select a term)
intoGenSLTM
Cancer3DSLTM(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETSLTM
MedgenSLTM
Genetic Testing Registry SLTM
NextProtQ9NWH9 [Medical]
TSGene79811
GENETestsSLTM
Target ValidationSLTM
Huge Navigator SLTM [HugePedia]
snp3D : Map Gene to Disease79811
BioCentury BCIQSLTM
ClinGenSLTM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79811
Chemical/Pharm GKB GenePA142670898
Clinical trialSLTM
Miscellaneous
canSAR (ICR)SLTM (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLTM
EVEXSLTM
GoPubMedSLTM
iHOPSLTM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 27 11:53:28 CEST 2018

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