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SMAP2 (small ArfGAP2)

Identity

Alias_namesSMAP1L
stromal membrane-associated protein 1-like
stromal membrane-associated GTPase-activating protein 2
Other alias
HGNC (Hugo) SMAP2
LocusID (NCBI) 64744
Atlas_Id 54643
Location 1p34.2  [Link to chromosome band 1p34]
Location_base_pair Starts at 40374633 and ends at 40423326 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PPIL1 (6p21.2) / SMAP2 (1p34.2)PTK2 (8q24.3) / SMAP2 (1p34.2)RLF (1p34.2) / SMAP2 (1p34.2)
SMAP2 (1p34.2) / CCT7 (2p13.2)SMAP2 (1p34.2) / MYCL (1p34.2)SMAP2 (1p34.2) / RPS24 (10q22.3)
SMAP2 (1p34.2) / SMAP2 (1p34.2)SMAP2 (1p34.2) / STXBP1 (9q34.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)SMAP2   25082
Cards
Entrez_Gene (NCBI)SMAP2  64744  small ArfGAP2
AliasesSMAP1L
GeneCards (Weizmann)SMAP2
Ensembl hg19 (Hinxton)ENSG00000084070 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000084070 [Gene_View]  chr1:40374633-40423326 [Contig_View]  SMAP2 [Vega]
ICGC DataPortalENSG00000084070
TCGA cBioPortalSMAP2
AceView (NCBI)SMAP2
Genatlas (Paris)SMAP2
WikiGenes64744
SOURCE (Princeton)SMAP2
Genetics Home Reference (NIH)SMAP2
Genomic and cartography
GoldenPath hg38 (UCSC)SMAP2  -     chr1:40374633-40423326 +  1p34.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SMAP2  -     1p34.2   [Description]    (hg19-Feb_2009)
EnsemblSMAP2 - 1p34.2 [CytoView hg19]  SMAP2 - 1p34.2 [CytoView hg38]
Mapping of homologs : NCBISMAP2 [Mapview hg19]  SMAP2 [Mapview hg38]
OMIM616916   
Gene and transcription
Genbank (Entrez)AK294675 AK298702 AK303975 AK308280 AK313105
RefSeq transcript (Entrez)NM_001198978 NM_001198979 NM_001198980 NM_022733
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SMAP2
Cluster EST : UnigeneHs.602551 [ NCBI ]
CGAP (NCI)Hs.602551
Alternative Splicing GalleryENSG00000084070
Gene ExpressionSMAP2 [ NCBI-GEO ]   SMAP2 [ EBI - ARRAY_EXPRESS ]   SMAP2 [ SEEK ]   SMAP2 [ MEM ]
Gene Expression Viewer (FireBrowse)SMAP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64744
GTEX Portal (Tissue expression)SMAP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WU79   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WU79  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WU79
Splice isoforms : SwissVarQ8WU79
PhosPhoSitePlusQ8WU79
Domaine pattern : Prosite (Expaxy)ARFGAP (PS50115)   
Domains : Interpro (EBI)ArfGAP   
Domain families : Pfam (Sanger)ArfGap (PF01412)   
Domain families : Pfam (NCBI)pfam01412   
Domain families : Smart (EMBL)ArfGap (SM00105)  
Conserved Domain (NCBI)SMAP2
DMDM Disease mutations64744
Blocks (Seattle)SMAP2
PDB (SRS)2IQJ   
PDB (PDBSum)2IQJ   
PDB (IMB)2IQJ   
PDB (RSDB)2IQJ   
Structural Biology KnowledgeBase2IQJ   
SCOP (Structural Classification of Proteins)2IQJ   
CATH (Classification of proteins structures)2IQJ   
SuperfamilyQ8WU79
Human Protein AtlasENSG00000084070
Peptide AtlasQ8WU79
HPRD12442
IPIIPI00102856   IPI00645261   IPI00982363   IPI00982954   IPI00645838   
Protein Interaction databases
DIP (DOE-UCLA)Q8WU79
IntAct (EBI)Q8WU79
FunCoupENSG00000084070
BioGRIDSMAP2
STRING (EMBL)SMAP2
ZODIACSMAP2
Ontologies - Pathways
QuickGOQ8WU79
Ontology : AmiGOGTPase activator activity  protein binding  cytoplasm  positive regulation of GTPase activity  metal ion binding  
Ontology : EGO-EBIGTPase activator activity  protein binding  cytoplasm  positive regulation of GTPase activity  metal ion binding  
Pathways : KEGGEndocytosis   
NDEx NetworkSMAP2
Atlas of Cancer Signalling NetworkSMAP2
Wikipedia pathwaysSMAP2
Orthology - Evolution
OrthoDB64744
GeneTree (enSembl)ENSG00000084070
Phylogenetic Trees/Animal Genes : TreeFamSMAP2
HOVERGENQ8WU79
HOGENOMQ8WU79
Homologs : HomoloGeneSMAP2
Homology/Alignments : Family Browser (UCSC)SMAP2
Gene fusions - Rearrangements
Fusion : MitelmanRLF/SMAP2 [1p34.2/1p34.2]  [t(1;1)(p34;p34)]  
Fusion : MitelmanSMAP2/MYCL [1p34.2/1p34.2]  [t(1;1)(p34;p34)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSMAP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SMAP2
dbVarSMAP2
ClinVarSMAP2
1000_GenomesSMAP2 
Exome Variant ServerSMAP2
ExAC (Exome Aggregation Consortium)SMAP2 (select the gene name)
Genetic variants : HAPMAP64744
Genomic Variants (DGV)SMAP2 [DGVbeta]
DECIPHERSMAP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSMAP2 
Mutations
ICGC Data PortalSMAP2 
TCGA Data PortalSMAP2 
Broad Tumor PortalSMAP2
OASIS PortalSMAP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSMAP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSMAP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SMAP2
DgiDB (Drug Gene Interaction Database)SMAP2
DoCM (Curated mutations)SMAP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SMAP2 (select a term)
intoGenSMAP2
Cancer3DSMAP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616916   
Orphanet
MedgenSMAP2
Genetic Testing Registry SMAP2
NextProtQ8WU79 [Medical]
TSGene64744
GENETestsSMAP2
Target ValidationSMAP2
Huge Navigator SMAP2 [HugePedia]
snp3D : Map Gene to Disease64744
BioCentury BCIQSMAP2
ClinGenSMAP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64744
Chemical/Pharm GKB GenePA162403939
Clinical trialSMAP2
Miscellaneous
canSAR (ICR)SMAP2 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSMAP2
EVEXSMAP2
GoPubMedSMAP2
iHOPSMAP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:56:28 CEST 2017

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