SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2)

Identity

Other names	BAF190
	BRM
	FLJ36757
	MGC74511
	SNF2
	SNF2L2
	SNF2LA
	SWI2
	Sth1p
	hBRM
	hSNF2a
HGNC	SMARCA2
Location	9p24.3
Location_base_pair	Starts at 2005342 and ends at 2183623 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	SMARCA2   11098
Entrez_Gene	SMARCA2  6595  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
	Cards
GeneCards	SMARCA2
Ensembl	SMARCA2 [Search_View]   ENSG00000080503 [Gene_View]
Genatlas	SMARCA2
GeneLynx	SMARCA2
eGenome	SMARCA2
euGene	6595
	Genomic and cartography
GoldenPath	SMARCA2  -  9p24.3   chr9:2005342-2183623 +  9p24.3   [Description]    (hg18-March_2006)
Ensembl	SMARCA2 - 9p24.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	SMARCA2
	Gene and transcription
Genbank	AK094076 [ ENTREZ ]
Genbank	AK296373 [ ENTREZ ]
Genbank	AK308941 [ ENTREZ ]
Genbank	AL558829 [ ENTREZ ]
Genbank	AY293824 [ ENTREZ ]
RefSeq	NM_003070 [ SRS ]    NM_003070 [ ENTREZ ]
RefSeq	NM_139045 [ SRS ]    NM_139045 [ ENTREZ ]
RefSeq	AC_000052 [ SRS ]    AC_000052 [ ENTREZ ]
RefSeq	AC_000141 [ SRS ]    AC_000141 [ ENTREZ ]
RefSeq	NC_000009 [ SRS ]    NC_000009 [ ENTREZ ]
RefSeq	NT_008413 [ SRS ]    NT_008413 [ ENTREZ ]
RefSeq	NW_001839149 [ SRS ]    NW_001839149 [ ENTREZ ]
RefSeq	NW_924062 [ SRS ]    NW_924062 [ ENTREZ ]
AceView	SMARCA2 AceView - NCBI
Unigene	Hs.298990 [ SRS ]    Hs.298990 [ NCBI ]     HS298990 [ spliceNest ]
Fast-db	1017 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P51531 [ SRS]    P51531 [ EXPASY ]     P51531 [ INTERPRO ]     P51531 [ UNIPROT ]
Prosite	PS00633 BROMODOMAIN_1 [ SRS ]    PS00633 BROMODOMAIN_1 [ Expasy ]
Prosite	PS50014 BROMODOMAIN_2 [ SRS ]    PS50014 BROMODOMAIN_2 [ Expasy ]
Prosite	PS51192 HELICASE_ATP_BIND_1 [ SRS ]    PS51192 HELICASE_ATP_BIND_1 [ Expasy ]
Prosite	PS51194 HELICASE_CTER [ SRS ]    PS51194 HELICASE_CTER [ Expasy ]
Prosite	PS51204 HSA [ SRS ]    PS51204 HSA [ Expasy ]
Interpro	IPR006576 BRK [ SRS ]    IPR006576 BRK [ EBI ]
Interpro	IPR001487 Bromodomain [ SRS ]    IPR001487 Bromodomain [ EBI ]
Interpro	IPR014001 DEAD-like_N [ SRS ]    IPR014001 DEAD-like_N [ EBI ]
Interpro	IPR001650 DNA/RNA_helicase_C [ SRS ]    IPR001650 DNA/RNA_helicase_C [ EBI ]
Interpro	IPR013999 HAS_subgroup [ SRS ]    IPR013999 HAS_subgroup [ EBI ]
Interpro	IPR014012 Helicase/SANT-assoc_DNA_bd [ SRS ]    IPR014012 Helicase/SANT-assoc_DNA_bd [ EBI ]
Interpro	IPR014021 Helicase_SF1/SF2_ATP-bd [ SRS ]    IPR014021 Helicase_SF1/SF2_ATP-bd [ EBI ]
Interpro	IPR006562 HSA [ SRS ]    IPR006562 HSA [ EBI ]
Interpro	IPR014978 QLQ [ SRS ]    IPR014978 QLQ [ EBI ]
Interpro	IPR000330 SNF2_N [ SRS ]    IPR000330 SNF2_N [ EBI ]
CluSTr	P51531
Pfam	PF00439 Bromodomain [ SRS ]    PF00439 Bromodomain [ Sanger ]    pfam00439 [ NCBI-CDD ]
Pfam	PF00271 Helicase_C [ SRS ]    PF00271 Helicase_C [ Sanger ]    pfam00271 [ NCBI-CDD ]
Pfam	PF07529 HSA [ SRS ]    PF07529 HSA [ Sanger ]    pfam07529 [ NCBI-CDD ]
Pfam	PF08880 QLQ [ SRS ]    PF08880 QLQ [ Sanger ]    pfam08880 [ NCBI-CDD ]
Pfam	PF00176 SNF2_N [ SRS ]    PF00176 SNF2_N [ Sanger ]    pfam00176 [ NCBI-CDD ]
Pfam	PF07533 TCH [ SRS ]    PF07533 TCH [ Sanger ]    pfam07533 [ NCBI-CDD ]
Smart	SM00592 BRK [EMBL]
Smart	SM00297 BROMO [EMBL]
Smart	SM00487 DEXDc [EMBL]
Smart	SM00490 HELICc [EMBL]
Smart	SM00573 HSA [EMBL]
Blocks	P51531
PDB	2DAT [ SRS ]    2DAT [ PdbSum ],   2DAT [ IMB ]   2DAT [ RSDB ]
HPRD	02483
	Protein Interaction databases
DIP	P51531
IntAct	P51531
	Polymorphism : SNP, mutations, diseases
OMIM	600014    [ map ]
GENECLINICS	600014
SNP	SMARCA2 [dbSNP-NCBI]
SNP	NM_003070 [SNP-NCI]
SNP	NM_139045 [SNP-NCI]
SNP	SMARCA2 [GeneSNPs - Utah]  SMARCA2] [HGBASE - SRS]
HAPMAP	SMARCA2 [HAPMAP]
COSMIC	SMARCA2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	SMARCA2
	General knowledge
Family Browser	SMARCA2 [UCSC Family Browser]
SOURCE	NM_003070
SOURCE	NM_139045
SMD	Hs.298990
SAGE	Hs.298990
Enzyme	3.6.1.- [ Enzyme-Expasy ]   3.6.1.- [ Enzyme-SRS ]   3.6.1.- [ IntEnz-EBI ]   3.6.1.- [ BRENDA ]   3.6.1.- [ KEGG ]   3.6.1.- [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	DNA binding [Amigo]  DNA binding
GO	transcription coactivator activity [Amigo]  transcription coactivator activity
GO	helicase activity [Amigo]  helicase activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	transcription [Amigo]  transcription
GO	regulation of transcription from RNA polymerase II promoter [Amigo]  regulation of transcription from RNA polymerase II promoter
GO	hydrolase activity [Amigo]  hydrolase activity
KEGG	Starch and sucrose metabolism
KEGG	Folate biosynthesis
PubGene	SMARCA2
TreeFam	SMARCA2
CTD	6595 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	SMARCA2 Related clones (RZPD - Berlin)
	PubMed
PubMed	56 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:32:50 2008