| Nomenclature |
|---|
| HGNC (Hugo) | SMARCA2 11098 |
| Cards |
|---|
| Entrez_Gene (NCBI) | SMARCA2 6595 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| GeneCards (Weizmann) | SMARCA2 |
| Ensembl hg19 (Hinxton) | ENSG00000080503 [Gene_View] chr9:2021945-2193623 [Contig_View] SMARCA2 [Vega] |
| Ensembl hg38 (Hinxton) | ENSG00000080503 [Gene_View] chr9:2021945-2193623 [Contig_View] SMARCA2 [Vega] |
| ICGC DataPortal | ENSG00000080503 |
| cBioPortal | SMARCA2 |
| AceView (NCBI) | SMARCA2 |
| Genatlas (Paris) | SMARCA2 |
| WikiGenes | 6595 |
| SOURCE (Princeton) | SMARCA2 |
| Genomic and cartography |
|---|
| GoldenPath hg19 (UCSC) | SMARCA2 - chr9:2021945-2193623 + 9p24.3 [Description] (hg19-Feb_2009) |
| GoldenPath hg38 (UCSC) | SMARCA2 - 9p24.3 [Description] (hg38-Dec_2013) |
| Ensembl | SMARCA2 - 9p24.3 [CytoView hg19] SMARCA2 - 9p24.3 [CytoView hg38] |
| Mapping of homologs : NCBI | SMARCA2 [Mapview hg19] SMARCA2 [Mapview hg38] |
| OMIM | 600014 601358 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK094076 AK296373 AK298045 AK299683 AK300093 |
| RefSeq transcript (Entrez) | NM_001289396 NM_001289397 NM_001289398 NM_001289399 NM_001289400 NM_003070 NM_139045 |
| RefSeq genomic (Entrez) | AC_000141 NC_000009 NC_018920 NG_032162 NT_008413 NW_001839149 NW_004929342 |
| Consensus coding sequences : CCDS (NCBI) | SMARCA2 |
| Cluster EST : Unigene | Hs.644901 [ NCBI ] |
| CGAP (NCI) | Hs.644901 |
| Alternative Splicing : Fast-db (Paris) | GSHG0029984 |
| Alternative Splicing Gallery | ENSG00000080503 |
| Gene Expression | SMARCA2 [ NCBI-GEO ] SMARCA2 [ SEEK ] SMARCA2 [ MEM ] |
| SOURCE (Princeton) | Expression in : [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P51531 (Uniprot) |
| NextProt | P51531 [Medical] |
| With graphics : InterPro | P51531 |
| Splice isoforms : SwissVar | P51531 (Swissvar) |
| Catalytic activity : Enzyme | 3.6.4.- [ Enzyme-Expasy ] 3.6.4.-3.6.4.- [ IntEnz-EBI ] 3.6.4.- [ BRENDA ] 3.6.4.- [ KEGG ] |
| Domaine pattern : Prosite (Expaxy) | BROMODOMAIN_1 (PS00633) BROMODOMAIN_2 (PS50014) HELICASE_ATP_BIND_1 (PS51192) HELICASE_CTER (PS51194) HSA (PS51204) QLQ (PS51666) |
| Domains : Interpro (EBI) | BRK_domain Bromodomain Bromodomain_CS Gln-Leu-Gln_QLQ HAS_subgr Helicase/SANT-assoc_DNA-bd Helicase_ATP-bd Helicase_C P-loop_NTPase SnAC SNF2_N |
| Related proteins : CluSTr | P51531 |
| Domain families : Pfam (Sanger) | BRK (PF07533) Bromodomain (PF00439) Helicase_C (PF00271) HSA (PF07529) QLQ (PF08880) SnAC (PF14619) SNF2_N (PF00176) |
| Domain families : Pfam (NCBI) | pfam07533 pfam00439 pfam00271 pfam07529 pfam08880 pfam14619 pfam00176 |
| Domain families : Smart (EMBL) | BRK (SM00592) BROMO (SM00297) DEXDc (SM00487) HELICc (SM00490) HSA (SM00573) QLQ (SM00951) |
| DMDM Disease mutations | 6595 |
| Blocks (Seattle) | P51531 |
| PDB (SRS) | 2DAT |
| PDB (PDBSum) | 2DAT |
| PDB (IMB) | 2DAT |
| PDB (RSDB) | 2DAT |
| Human Protein Atlas | ENSG00000080503 |
| Peptide Atlas | P51531 |
| HPRD | 02483 |
| IPI | IPI00514648 IPI00386718 IPI00647560 IPI00647028 IPI00641350 IPI00641050 IPI00640353 IPI00642503 IPI00103451 IPI00643691 IPI00640994 IPI00644329 IPI00645885 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P51531 |
| IntAct (EBI) | P51531 |
| FunCoup | ENSG00000080503 |
| BioGRID | SMARCA2 |
| IntegromeDB | SMARCA2 |
| STRING (EMBL) | SMARCA2 |
| Ontologies - Pathways |
|---|
| QuickGO | P51531 |
| Ontology : AmiGO | negative regulation of transcription from RNA polymerase II promoter nuclear chromatin RNA polymerase II transcription coactivator activity transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm nucleolus ATP catabolic process chromatin remodeling transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter nervous system development DNA-dependent ATPase activity negative regulation of cell proliferation SWI/SNF complex negative regulation of cell growth aortic smooth muscle cell differentiation histone binding intracellular membrane-bounded organelle transcription regulatory region DNA binding intermediate filament cytoskeleton negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter npBAF complex nBAF complex |
| Ontology : EGO-EBI | negative regulation of transcription from RNA polymerase II promoter nuclear chromatin RNA polymerase II transcription coactivator activity transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm nucleolus ATP catabolic process chromatin remodeling transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter nervous system development DNA-dependent ATPase activity negative regulation of cell proliferation SWI/SNF complex negative regulation of cell growth aortic smooth muscle cell differentiation histone binding intracellular membrane-bounded organelle transcription regulatory region DNA binding intermediate filament cytoskeleton negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter npBAF complex nBAF complex |
| Protein Interaction Database | SMARCA2 |
| DoCM (Curated mutations) | SMARCA2 |
| Wikipedia pathways | SMARCA2 |
| Gene fusion - rearrangements |
|---|
| Polymorphisms : SNP, variants |
|---|
| NCBI Variation Viewer | SMARCA2 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | SMARCA2 |
| dbVar | SMARCA2 |
| ClinVar | SMARCA2 |
| 1000_Genomes | SMARCA2 |
| Exome Variant Server | SMARCA2 |
| SNP (GeneSNP Utah) | SMARCA2 |
| SNP : HGBase | SMARCA2 |
| Genetic variants : HAPMAP | SMARCA2 |
| Genomic Variants (DGV) | SMARCA2 [DGVbeta] |
| Mutations |
|---|
| ICGC Data Portal | ENSG00000080503 |
| Somatic Mutations in Cancer : COSMIC | SMARCA2 |
| CONAN: Copy Number Analysis | SMARCA2 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] |
| Diseases |
|---|
| DECIPHER (Syndromes) | 9:2021945-2193623 |
| Mutations and Diseases : HGMD | SMARCA2 |
| OMIM | 600014 601358 |
| Medgen | SMARCA2 |
| NextProt | P51531 [Medical] |
| GENETests | SMARCA2 |
| Disease Genetic Association | SMARCA2 |
| Huge Navigator |
SMARCA2 [HugePedia] SMARCA2 [HugeCancerGEM] |
| snp3D : Map Gene to Disease | 6595 |
| DGIdb (Drug Gene Interaction db) | SMARCA2 |
| General knowledge |
|---|
| Homologs : HomoloGene | SMARCA2 |
| Homology/Alignments : Family Browser (UCSC) | SMARCA2 |
| Phylogenetic Trees/Animal Genes : TreeFam | SMARCA2 |
| Chemical/Protein Interactions : CTD | 6595 |
| Chemical/Pharm GKB Gene | PA35948 |
| Clinical trial | SMARCA2 |
| Cancer Resource (Charite) | ENSG00000080503 |
| Other databases |
|---|
| Probes |
|---|
| Litterature |
|---|
| PubMed | 144 Pubmed reference(s) in Entrez |
| CoreMine | SMARCA2 |
| GoPubMed | SMARCA2 |
| iHOP | SMARCA2 |
