SMCR8 (SMCR8-C9orf72 complex subunit)

2014-11-01  

Identity

HGNC
LOCATION
17p11.2
LOCUSID
ALIAS
DENND8A
FUSION GENES

Other Information

Locus ID:

NCBI: 140775
MIM: 617074
HGNC: 17921
Ensembl: ENSG00000176994

Variants:

dbSNP: 140775
ClinVar: 140775
TCGA: ENSG00000176994
COSMIC: SMCR8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176994ENST00000406438Q8TEV9

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
271931902016The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway.78
281955312017Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator.28

Citation

Dessen P

SMCR8 (SMCR8-C9orf72 complex subunit)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73546/smcr8