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SMS (spermine synthase)

Identity

Other namesMRSR
SPMSY
SRS
SpS
HGNC (Hugo) SMS
LocusID (NCBI) 6611
Atlas_Id 53256
Location Xp22.11  [Link to chromosome band Xp22]
Location_base_pair Starts at 21958691 and ends at 22012955 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SMS   11123
Cards
Entrez_Gene (NCBI)SMS  6611  spermine synthase
AliasesMRSR; SPMSY; SRS; SpS
GeneCards (Weizmann)SMS
Ensembl hg19 (Hinxton)ENSG00000102172 [Gene_View]  chrX:21958691-22012955 [Contig_View]  SMS [Vega]
Ensembl hg38 (Hinxton)ENSG00000102172 [Gene_View]  chrX:21958691-22012955 [Contig_View]  SMS [Vega]
ICGC DataPortalENSG00000102172
TCGA cBioPortalSMS
AceView (NCBI)SMS
Genatlas (Paris)SMS
WikiGenes6611
SOURCE (Princeton)SMS
Genomic and cartography
GoldenPath hg19 (UCSC)SMS  -     chrX:21958691-22012955 +  Xp22.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SMS  -     Xp22.11   [Description]    (hg38-Dec_2013)
EnsemblSMS - Xp22.11 [CytoView hg19]  SMS - Xp22.11 [CytoView hg38]
Mapping of homologs : NCBISMS [Mapview hg19]  SMS [Mapview hg38]
OMIM300105   309583   
Gene and transcription
Genbank (Entrez)AD001528 AK293455 AK313834 BC009898 BC085621
RefSeq transcript (Entrez)NM_001258423 NM_004595
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_009228 NT_167197 NW_004929438
Consensus coding sequences : CCDS (NCBI)SMS
Cluster EST : UnigeneHs.724874 [ NCBI ]
CGAP (NCI)Hs.724874
Alternative Splicing GalleryENSG00000102172
Gene ExpressionSMS [ NCBI-GEO ]   SMS [ EBI - ARRAY_EXPRESS ]   SMS [ SEEK ]   SMS [ MEM ]
Gene Expression Viewer (FireBrowse)SMS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6611
GTEX Portal (Tissue expression)SMS
Protein : pattern, domain, 3D structure
UniProt/SwissProtP52788 (Uniprot)
NextProtP52788  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP52788
Splice isoforms : SwissVarP52788 (Swissvar)
Catalytic activity : Enzyme2.5.1.22 [ Enzyme-Expasy ]   2.5.1.222.5.1.22 [ IntEnz-EBI ]   2.5.1.22 [ BRENDA ]   2.5.1.22 [ KEGG ]   
PhosPhoSitePlusP52788
Domaine pattern : Prosite (Expaxy)PABS_1 (PS01330)    PABS_2 (PS51006)   
Domains : Interpro (EBI)PABS    PABS_CS    SAM-dependent_MTases    Spermine_synthase_animal   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations6611
Blocks (Seattle)SMS
PDB (SRS)3C6K    3C6M   
PDB (PDBSum)3C6K    3C6M   
PDB (IMB)3C6K    3C6M   
PDB (RSDB)3C6K    3C6M   
Structural Biology KnowledgeBase3C6K    3C6M   
SCOP (Structural Classification of Proteins)3C6K    3C6M   
CATH (Classification of proteins structures)3C6K    3C6M   
SuperfamilyP52788
Human Protein AtlasENSG00000102172
Peptide AtlasP52788
HPRD02115
IPIIPI00005102   IPI00642393   IPI00909795   IPI00643452   
Protein Interaction databases
DIP (DOE-UCLA)P52788
IntAct (EBI)P52788
FunCoupENSG00000102172
BioGRIDSMS
STRING (EMBL)SMS
ZODIACSMS
Ontologies - Pathways
QuickGOP52788
Ontology : AmiGOcytosol  methionine metabolic process  polyamine metabolic process  spermine biosynthetic process  spermine biosynthetic process  spermine synthase activity  spermine synthase activity  extracellular exosome  
Ontology : EGO-EBIcytosol  methionine metabolic process  polyamine metabolic process  spermine biosynthetic process  spermine biosynthetic process  spermine synthase activity  spermine synthase activity  extracellular exosome  
Pathways : KEGGCysteine and methionine metabolism    Arginine and proline metabolism    beta-Alanine metabolism    Glutathione metabolism   
NDEx NetworkSMS
Atlas of Cancer Signalling NetworkSMS
Wikipedia pathwaysSMS
Orthology - Evolution
OrthoDB6611
GeneTree (enSembl)ENSG00000102172
Phylogenetic Trees/Animal Genes : TreeFamSMS
Homologs : HomoloGeneSMS
Homology/Alignments : Family Browser (UCSC)SMS
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerSMS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SMS
dbVarSMS
ClinVarSMS
1000_GenomesSMS 
Exome Variant ServerSMS
ExAC (Exome Aggregation Consortium)SMS (select the gene name)
Genetic variants : HAPMAP6611
Genomic Variants (DGV)SMS [DGVbeta]
Mutations
ICGC Data PortalSMS 
TCGA Data PortalSMS 
Broad Tumor PortalSMS
OASIS PortalSMS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSMS 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch SMS
DgiDB (Drug Gene Interaction Database)SMS
DoCM (Curated mutations)SMS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SMS (select a term)
intoGenSMS
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)X:21958691-22012955  ENSG00000102172
CONAN: Copy Number AnalysisSMS 
Mutations and Diseases : HGMDSMS
OMIM300105    309583   
MedgenSMS
Genetic Testing Registry SMS
NextProtP52788 [Medical]
TSGene6611
GENETestsSMS
Huge Navigator SMS [HugePedia]
snp3D : Map Gene to Disease6611
BioCentury BCIQSMS
ClinGenSMS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6611
Chemical/Pharm GKB GenePA35972
Clinical trialSMS
Miscellaneous
canSAR (ICR)SMS (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSMS
EVEXSMS
GoPubMedSMS
iHOPSMS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 19:14:10 CEST 2016

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