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SMS (spermine synthase)

Identity

Other namesMRSR
SPMSY
SRS
SpS
HGNC (Hugo) SMS
LocusID (NCBI) 6611
Location Xp22.11
Location_base_pair Starts at 21958691 and ends at 22012955 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)SMS   11123
Cards
Entrez_Gene (NCBI)SMS  6611  spermine synthase
GeneCards (Weizmann)SMS
Ensembl (Hinxton)ENSG00000102172 [Gene_View]  chrX:21958691-22012955 [Contig_View]  SMS [Vega]
ICGC DataPortalENSG00000102172
AceView (NCBI)SMS
Genatlas (Paris)SMS
WikiGenes6611
SOURCE (Princeton)NM_001258423 NM_004595
Genomic and cartography
GoldenPath (UCSC)SMS  -  Xp22.11   chrX:21958691-22012955 +  Xp22.11   [Description]    (hg19-Feb_2009)
EnsemblSMS - Xp22.11 [CytoView]
Mapping of homologs : NCBISMS [Mapview]
OMIM300105   309583   
Gene and transcription
Genbank (Entrez)AD001528 AK293455 AK313834 BC009898 BC085621
RefSeq transcript (Entrez)NM_001258423 NM_004595
RefSeq genomic (Entrez)AC_000155 NC_000023 NC_018934 NG_009228 NT_167197 NW_001842360 NW_004929438
Consensus coding sequences : CCDS (NCBI)SMS
Cluster EST : UnigeneHs.724874 [ NCBI ]
CGAP (NCI)Hs.724874
Alternative Splicing : Fast-db (Paris)GSHG0031419
Alternative Splicing GalleryENSG00000102172
Gene ExpressionSMS [ NCBI-GEO ]     SMS [ SEEK ]   SMS [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP52788 (Uniprot)
NextProtP52788  [Medical]
With graphics : InterProP52788
Splice isoforms : SwissVarP52788 (Swissvar)
Catalytic activity : Enzyme2.5.1.22 [ Enzyme-Expasy ]   2.5.1.222.5.1.22 [ IntEnz-EBI ]   2.5.1.22 [ BRENDA ]   2.5.1.22 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)PABS_1 (PS01330)    PABS_2 (PS51006)   
Domains : Interpro (EBI)SAM-dependent_MTases-like    Spermidine/spermine_synthase    Spermine_synthase_animal   
Related proteins : CluSTrP52788
Domain families : Pfam (Sanger)Spermine_synth (PF01564)   
Domain families : Pfam (NCBI)pfam01564   
DMDM Disease mutations6611
Blocks (Seattle)P52788
PDB (SRS)3C6K    3C6M   
PDB (PDBSum)3C6K    3C6M   
PDB (IMB)3C6K    3C6M   
PDB (RSDB)3C6K    3C6M   
Human Protein AtlasENSG00000102172
Peptide AtlasP52788
HPRD02115
IPIIPI00005102   IPI00642393   IPI00909795   IPI00643452   
Protein Interaction databases
DIP (DOE-UCLA)P52788
IntAct (EBI)P52788
FunCoupENSG00000102172
BioGRIDSMS
IntegromeDBSMS
STRING (EMBL)SMS
Ontologies - Pathways
QuickGOP52788
Ontology : AmiGOspermidine synthase activity  cytosol  methionine metabolic process  polyamine metabolic process  spermine biosynthetic process  spermine synthase activity  cellular nitrogen compound metabolic process  small molecule metabolic process  extracellular vesicular exosome  
Ontology : EGO-EBIspermidine synthase activity  cytosol  methionine metabolic process  polyamine metabolic process  spermine biosynthetic process  spermine synthase activity  cellular nitrogen compound metabolic process  small molecule metabolic process  extracellular vesicular exosome  
Pathways : KEGGCysteine and methionine metabolism    Arginine and proline metabolism    beta-Alanine metabolism    Glutathione metabolism   
Protein Interaction DatabaseSMS
Wikipedia pathwaysSMS
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SMS
SNP (GeneSNP Utah)SMS
SNP : HGBaseSMS
Genetic variants : HAPMAPSMS
1000_GenomesSMS 
ICGC programENSG00000102172 
CONAN: Copy Number AnalysisSMS 
Somatic Mutations in Cancer : COSMICSMS 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
DECIPHER (Syndromes)X:21958691-22012955
Mutations and Diseases : HGMDSMS
OMIM300105    309583   
MedgenSMS
GENETestsSMS
Disease Genetic AssociationSMS
Huge Navigator SMS [HugePedia]  SMS [HugeCancerGEM]
Genomic VariantsSMS  SMS [DGVbeta]
Exome VariantSMS
dbVarSMS
ClinVarSMS
snp3D : Map Gene to Disease6611
General knowledge
Homologs : HomoloGeneSMS
Homology/Alignments : Family Browser (UCSC)SMS
Phylogenetic Trees/Animal Genes : TreeFamSMS
Chemical/Protein Interactions : CTD6611
Chemical/Pharm GKB GenePA35972
Clinical trialSMS
Cancer Resource (Charite)ENSG00000102172
Other databases
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
CoreMineSMS
GoPubMedSMS
iHOPSMS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 17:58:00 CET 2014

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