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SMUG1 (single-strand-selective monofunctional uracil-DNA glycosylase 1)

Identity

Alias_symbol (synonym)UNG3
FDG
HMUDG
Other alias
HGNC (Hugo) SMUG1
LocusID (NCBI) 23583
Atlas_Id 42341
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 54180358 and ends at 54188994 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SMUG1 (12q13.13) / PPP2R5A (1q32.3)SMUG1 12q13.13 / PPP2R5A 1q32.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SMUG1   17148
Cards
Entrez_Gene (NCBI)SMUG1  23583  single-strand-selective monofunctional uracil-DNA glycosylase 1
AliasesFDG; HMUDG; UNG3
GeneCards (Weizmann)SMUG1
Ensembl hg19 (Hinxton)ENSG00000123415 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123415 [Gene_View]  chr12:54180358-54188994 [Contig_View]  SMUG1 [Vega]
ICGC DataPortalENSG00000123415
TCGA cBioPortalSMUG1
AceView (NCBI)SMUG1
Genatlas (Paris)SMUG1
WikiGenes23583
SOURCE (Princeton)SMUG1
Genetics Home Reference (NIH)SMUG1
Genomic and cartography
GoldenPath hg38 (UCSC)SMUG1  -     chr12:54180358-54188994 -  12q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SMUG1  -     12q13.13   [Description]    (hg19-Feb_2009)
EnsemblSMUG1 - 12q13.13 [CytoView hg19]  SMUG1 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBISMUG1 [Mapview hg19]  SMUG1 [Mapview hg38]
OMIM607753   
Gene and transcription
Genbank (Entrez)AF125182 AI002776 AK001235 AK001789 AK091468
RefSeq transcript (Entrez)NM_001243787 NM_001243788 NM_001243789 NM_001243790 NM_001243791 NM_014311
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SMUG1
Cluster EST : UnigeneHs.731659 [ NCBI ]
CGAP (NCI)Hs.731659
Alternative Splicing GalleryENSG00000123415
Gene ExpressionSMUG1 [ NCBI-GEO ]   SMUG1 [ EBI - ARRAY_EXPRESS ]   SMUG1 [ SEEK ]   SMUG1 [ MEM ]
Gene Expression Viewer (FireBrowse)SMUG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23583
GTEX Portal (Tissue expression)SMUG1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ53HV7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ53HV7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ53HV7
Splice isoforms : SwissVarQ53HV7
PhosPhoSitePlusQ53HV7
Domains : Interpro (EBI)Uracil-DNA_glycosylase-like   
Domain families : Pfam (Sanger)UDG (PF03167)   
Domain families : Pfam (NCBI)pfam03167   
Conserved Domain (NCBI)SMUG1
DMDM Disease mutations23583
Blocks (Seattle)SMUG1
SuperfamilyQ53HV7
Human Protein AtlasENSG00000123415
Peptide AtlasQ53HV7
HPRD06376
IPIIPI00003780   IPI00385823   IPI00965921   IPI00798251   IPI00964926   IPI00966581   IPI00965665   IPI00796263   IPI00966337   IPI00968038   
Protein Interaction databases
DIP (DOE-UCLA)Q53HV7
IntAct (EBI)Q53HV7
FunCoupENSG00000123415
BioGRIDSMUG1
STRING (EMBL)SMUG1
ZODIACSMUG1
Ontologies - Pathways
QuickGOQ53HV7
Ontology : AmiGOoxidized pyrimidine nucleobase lesion DNA N-glycosylase activity  DNA binding  uracil DNA N-glycosylase activity  protein binding  nucleoplasm  nucleolus  base-excision repair  single-strand selective uracil DNA N-glycosylase activity  single-strand selective uracil DNA N-glycosylase activity  DNA N-glycosylase activity  depyrimidination  
Ontology : EGO-EBIoxidized pyrimidine nucleobase lesion DNA N-glycosylase activity  DNA binding  uracil DNA N-glycosylase activity  protein binding  nucleoplasm  nucleolus  base-excision repair  single-strand selective uracil DNA N-glycosylase activity  single-strand selective uracil DNA N-glycosylase activity  DNA N-glycosylase activity  depyrimidination  
Pathways : KEGGBase excision repair   
NDEx NetworkSMUG1
Atlas of Cancer Signalling NetworkSMUG1
Wikipedia pathwaysSMUG1
Orthology - Evolution
OrthoDB23583
GeneTree (enSembl)ENSG00000123415
Phylogenetic Trees/Animal Genes : TreeFamSMUG1
HOVERGENQ53HV7
HOGENOMQ53HV7
Homologs : HomoloGeneSMUG1
Homology/Alignments : Family Browser (UCSC)SMUG1
Gene fusions - Rearrangements
Fusion : MitelmanSMUG1/PPP2R5A [12q13.13/1q32.3]  
Fusion: TCGASMUG1 12q13.13 PPP2R5A 1q32.3 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSMUG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SMUG1
dbVarSMUG1
ClinVarSMUG1
1000_GenomesSMUG1 
Exome Variant ServerSMUG1
ExAC (Exome Aggregation Consortium)SMUG1 (select the gene name)
Genetic variants : HAPMAP23583
Genomic Variants (DGV)SMUG1 [DGVbeta]
DECIPHERSMUG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSMUG1 
Mutations
ICGC Data PortalSMUG1 
TCGA Data PortalSMUG1 
Broad Tumor PortalSMUG1
OASIS PortalSMUG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSMUG1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSMUG1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SMUG1
DgiDB (Drug Gene Interaction Database)SMUG1
DoCM (Curated mutations)SMUG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SMUG1 (select a term)
intoGenSMUG1
Cancer3DSMUG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607753   
Orphanet
MedgenSMUG1
Genetic Testing Registry SMUG1
NextProtQ53HV7 [Medical]
TSGene23583
GENETestsSMUG1
Target ValidationSMUG1
Huge Navigator SMUG1 [HugePedia]
snp3D : Map Gene to Disease23583
BioCentury BCIQSMUG1
ClinGenSMUG1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23583
Chemical/Pharm GKB GenePA142670895
Clinical trialSMUG1
Miscellaneous
canSAR (ICR)SMUG1 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSMUG1
EVEXSMUG1
GoPubMedSMUG1
iHOPSMUG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:07:59 CEST 2017

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