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SMYD1 (SET and MYND domain containing 1)

Identity

Alias_symbol (synonym)BOP
ZMYND22
KMT3D
Other aliasZMYND18
HGNC (Hugo) SMYD1
LocusID (NCBI) 150572
Atlas_Id 47425
Location 2p11.2  [Link to chromosome band 2p11]
Location_base_pair Starts at 88067780 and ends at 88113383 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SMYD1   20986
Cards
Entrez_Gene (NCBI)SMYD1  150572  SET and MYND domain containing 1
AliasesBOP; KMT3D; ZMYND18; ZMYND22
GeneCards (Weizmann)SMYD1
Ensembl hg19 (Hinxton)ENSG00000115593 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115593 [Gene_View]  chr2:88067780-88113383 [Contig_View]  SMYD1 [Vega]
ICGC DataPortalENSG00000115593
TCGA cBioPortalSMYD1
AceView (NCBI)SMYD1
Genatlas (Paris)SMYD1
WikiGenes150572
SOURCE (Princeton)SMYD1
Genetics Home Reference (NIH)SMYD1
Genomic and cartography
GoldenPath hg38 (UCSC)SMYD1  -     chr2:88067780-88113383 +  2p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SMYD1  -     2p11.2   [Description]    (hg19-Feb_2009)
EnsemblSMYD1 - 2p11.2 [CytoView hg19]  SMYD1 - 2p11.2 [CytoView hg38]
Mapping of homologs : NCBISMYD1 [Mapview hg19]  SMYD1 [Mapview hg38]
OMIM606846   
Gene and transcription
Genbank (Entrez)AF086123 AK022290 AK091724 AL832035 AY518933
RefSeq transcript (Entrez)NM_001330364 NM_198274
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SMYD1
Cluster EST : UnigeneHs.516176 [ NCBI ]
CGAP (NCI)Hs.516176
Alternative Splicing GalleryENSG00000115593
Gene ExpressionSMYD1 [ NCBI-GEO ]   SMYD1 [ EBI - ARRAY_EXPRESS ]   SMYD1 [ SEEK ]   SMYD1 [ MEM ]
Gene Expression Viewer (FireBrowse)SMYD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)150572
GTEX Portal (Tissue expression)SMYD1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NB12   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NB12  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NB12
Splice isoforms : SwissVarQ8NB12
Catalytic activity : Enzyme2.1.1.43 [ Enzyme-Expasy ]   2.1.1.432.1.1.43 [ IntEnz-EBI ]   2.1.1.43 [ BRENDA ]   2.1.1.43 [ KEGG ]   
PhosPhoSitePlusQ8NB12
Domaine pattern : Prosite (Expaxy)SET (PS50280)    ZF_MYND_1 (PS01360)    ZF_MYND_2 (PS50865)   
Domains : Interpro (EBI)SET_dom    Znf_MYND   
Domain families : Pfam (Sanger)SET (PF00856)    zf-MYND (PF01753)   
Domain families : Pfam (NCBI)pfam00856    pfam01753   
Domain families : Smart (EMBL)SET (SM00317)  
Conserved Domain (NCBI)SMYD1
DMDM Disease mutations150572
Blocks (Seattle)SMYD1
SuperfamilyQ8NB12
Human Protein AtlasENSG00000115593
Peptide AtlasQ8NB12
HPRD06025
IPIIPI00168081   IPI00926293   IPI00927474   
Protein Interaction databases
DIP (DOE-UCLA)Q8NB12
IntAct (EBI)Q8NB12
FunCoupENSG00000115593
BioGRIDSMYD1
STRING (EMBL)SMYD1
ZODIACSMYD1
Ontologies - Pathways
QuickGOQ8NB12
Ontology : AmiGODNA binding  transcription corepressor activity  protein binding  nucleus  cytoplasm  chromatin remodeling  transcription, DNA-templated  heart development  positive regulation of myotube differentiation  histone-lysine N-methyltransferase activity  histone lysine methylation  skeletal muscle cell differentiation  positive regulation of myoblast differentiation  negative regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBIDNA binding  transcription corepressor activity  protein binding  nucleus  cytoplasm  chromatin remodeling  transcription, DNA-templated  heart development  positive regulation of myotube differentiation  histone-lysine N-methyltransferase activity  histone lysine methylation  skeletal muscle cell differentiation  positive regulation of myoblast differentiation  negative regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkSMYD1
Atlas of Cancer Signalling NetworkSMYD1
Wikipedia pathwaysSMYD1
Orthology - Evolution
OrthoDB150572
GeneTree (enSembl)ENSG00000115593
Phylogenetic Trees/Animal Genes : TreeFamSMYD1
HOVERGENQ8NB12
HOGENOMQ8NB12
Homologs : HomoloGeneSMYD1
Homology/Alignments : Family Browser (UCSC)SMYD1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSMYD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SMYD1
dbVarSMYD1
ClinVarSMYD1
1000_GenomesSMYD1 
Exome Variant ServerSMYD1
ExAC (Exome Aggregation Consortium)SMYD1 (select the gene name)
Genetic variants : HAPMAP150572
Genomic Variants (DGV)SMYD1 [DGVbeta]
DECIPHERSMYD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSMYD1 
Mutations
ICGC Data PortalSMYD1 
TCGA Data PortalSMYD1 
Broad Tumor PortalSMYD1
OASIS PortalSMYD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSMYD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSMYD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SMYD1
DgiDB (Drug Gene Interaction Database)SMYD1
DoCM (Curated mutations)SMYD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SMYD1 (select a term)
intoGenSMYD1
Cancer3DSMYD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606846   
Orphanet
MedgenSMYD1
Genetic Testing Registry SMYD1
NextProtQ8NB12 [Medical]
TSGene150572
GENETestsSMYD1
Target ValidationSMYD1
Huge Navigator SMYD1 [HugePedia]
snp3D : Map Gene to Disease150572
BioCentury BCIQSMYD1
ClinGenSMYD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD150572
Chemical/Pharm GKB GenePA134862943
Clinical trialSMYD1
Miscellaneous
canSAR (ICR)SMYD1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSMYD1
EVEXSMYD1
GoPubMedSMYD1
iHOPSMYD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:15:11 CEST 2017

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