SNAP23 (synaptosome associated protein 23)

2008-12-01  

Identity

HGNC
LOCATION
15q15.1
LOCUSID
ALIAS
HsT17016,SNAP-23,SNAP23A,SNAP23B
FUSION GENES

Other Information

Locus ID:

NCBI: 8773
MIM: 602534
HGNC: 11131
Ensembl: ENSG00000092531

Variants:

dbSNP: 8773
ClinVar: 8773
TCGA: ENSG00000092531
COSMIC: SNAP23

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000092531ENST00000249647O00161
ENSG00000092531ENST00000249647A8K287
ENSG00000092531ENST00000349777O00161
ENSG00000092531ENST00000349777A0A024R9R8
ENSG00000092531ENST00000397138O00161
ENSG00000092531ENST00000397138A0A024R9R8
ENSG00000092531ENST00000561526H3BM38
ENSG00000092531ENST00000563765H3BU94
ENSG00000092531ENST00000563830H3BQY9
ENSG00000092531ENST00000563873H3BR99
ENSG00000092531ENST00000564153H3BPJ0
ENSG00000092531ENST00000566035H3BNG6
ENSG00000092531ENST00000566327H3BV99
ENSG00000092531ENST00000567094H3BNE1
ENSG00000092531ENST00000568331H3BNE1
ENSG00000092531ENST00000568451H3BNE1
ENSG00000092531ENST00000568841H3BP15
ENSG00000092531ENST00000568859H3BR18
ENSG00000092531ENST00000626061H3BU94
ENSG00000092531ENST00000627440H3BNG6

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
SNARE interactions in vesicular transportKEGGko04130
SNARE interactions in vesicular transportKEGGhsa04130
Platelet activationKEGGhsa04611
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing-Cross presentationREACTOMER-HSA-1236975
ER-Phagosome pathwayREACTOMER-HSA-1236974
Innate Immune SystemREACTOMER-HSA-168249
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
trans-Golgi Network Vesicle BuddingREACTOMER-HSA-199992
Clathrin derived vesicle buddingREACTOMER-HSA-421837
Translocation of GLUT4 to the plasma membraneREACTOMER-HSA-1445148
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
216425402011Granule exocytosis contributes to priming and activation of the human neutrophil respiratory burst.46
199104952009VAMP3, syntaxin-13 and SNAP23 are involved in secretion of matrix metalloproteinases, degradation of the extracellular matrix and cell invasion.45
205195162010Palmitoylation of the SNAP25 protein family: specificity and regulation by DHHC palmitoyl transferases.43
280672302017Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23.43
217683612011Synaptic vesicle-like lipidome of human cytomegalovirus virions reveals a role for SNARE machinery in virion egress.40
190860532009Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.34
129308252003Phosphorylation of SNAP-23 in activated human platelets.30
204160772010Identification of type 2 diabetes-associated combination of SNPs using support vector machine.26
244964512014SNARE-dependent interaction of Src, EGFR and β1 integrin regulates invadopodia formation and tumor cell invasion.24
219818322011SNAP-23 and syntaxin-3 are required for chemokine release by mature human mast cells.21

Citation

Dessen P

SNAP23 (synaptosome associated protein 23)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50583/snap23