Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9627
MIM: 603779
HGNC: 11139
Ensembl: ENSG00000064692
Variants:
dbSNP: 9627
ClinVar: 9627
TCGA: ENSG00000064692
COSMIC: SNCAIP
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Parkinson's disease | KEGG | hsa05012 |
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Amyloid fiber formation | REACTOME | R-HSA-977225 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38700150 | 2024 | Exploring Structural Insights of Aβ42 and α-Synuclein Monomers and Heterodimer: A Comparative Study Using Implicit and Explicit Solvent Simulations. | 0 |
| 38700150 | 2024 | Exploring Structural Insights of Aβ42 and α-Synuclein Monomers and Heterodimer: A Comparative Study Using Implicit and Explicit Solvent Simulations. | 0 |
| 30316984 | 2019 | Synphilin-1 has neuroprotective effects on MPP(+)-induced Parkinson's disease model cells by inhibiting ROS production and apoptosis. | 12 |
| 30316984 | 2019 | Synphilin-1 has neuroprotective effects on MPP(+)-induced Parkinson's disease model cells by inhibiting ROS production and apoptosis. | 12 |
| 26465922 | 2016 | Altered α-synuclein, parkin, and synphilin isoform levels in multiple system atrophy brains. | 21 |
| 26465922 | 2016 | Altered α-synuclein, parkin, and synphilin isoform levels in multiple system atrophy brains. | 21 |
| 24829096 | 2014 | Behavioral characterization of the hyperphagia synphilin-1 overexpressing mice. | 5 |
| 25545246 | 2014 | Synphilin-1 binds ATP and regulates intracellular energy status. | 6 |
| 24829096 | 2014 | Behavioral characterization of the hyperphagia synphilin-1 overexpressing mice. | 5 |
| 25545246 | 2014 | Synphilin-1 binds ATP and regulates intracellular energy status. | 6 |
| 22828940 | 2012 | Synphilin-1 alters metabolic homeostasis in a novel Drosophila obesity model. | 23 |
| 22828940 | 2012 | Synphilin-1 alters metabolic homeostasis in a novel Drosophila obesity model. | 23 |
| 20816781 | 2011 | α-synuclein aggregation reduces nigral myocyte enhancer factor-2D in idiopathic and experimental Parkinson's disease. | 12 |
| 21103907 | 2011 | Synphilin-1 inhibits alpha-synuclein degradation by the proteasome. | 16 |
| 21344240 | 2011 | Identification of Parkinson's disease candidate genes using CAESAR and screening of MAPT and SNCAIP in South African Parkinson's disease patients. | 5 |
Citation
Dessen P
SNCAIP (synuclein alpha interacting protein)
Atlas Genet Cytogenet Oncol Haematol. 2008-12-01
Online version: http://atlasgeneticsoncology.org/gene/50484/sncaip
