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SNCAIP (synuclein alpha interacting protein)

Identity

Alias_symbol (synonym)SYPH1
Other aliasSph1
HGNC (Hugo) SNCAIP
LocusID (NCBI) 9627
Atlas_Id 50484
Location 5q23.2  [Link to chromosome band 5q23]
Location_base_pair Starts at 122312069 and ends at 122464219 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PRDX5 (11q13.1) / SNCAIP (5q23.2)SNCAIP (5q23.2) / DNAJC10 (2q32.1)SNCAIP (5q23.2) / SNCAIP (5q23.2)
SNX24 (5q23.2) / SNCAIP (5q23.2)SNX24 5q23.2 / SNCAIP 5q23.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SNCAIP   11139
Cards
Entrez_Gene (NCBI)SNCAIP  9627  synuclein alpha interacting protein
AliasesSYPH1; Sph1
GeneCards (Weizmann)SNCAIP
Ensembl hg19 (Hinxton)ENSG00000064692 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000064692 [Gene_View]  chr5:122312069-122464219 [Contig_View]  SNCAIP [Vega]
ICGC DataPortalENSG00000064692
TCGA cBioPortalSNCAIP
AceView (NCBI)SNCAIP
Genatlas (Paris)SNCAIP
WikiGenes9627
SOURCE (Princeton)SNCAIP
Genetics Home Reference (NIH)SNCAIP
Genomic and cartography
GoldenPath hg38 (UCSC)SNCAIP  -     chr5:122312069-122464219 +  5q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SNCAIP  -     5q23.2   [Description]    (hg19-Feb_2009)
EnsemblSNCAIP - 5q23.2 [CytoView hg19]  SNCAIP - 5q23.2 [CytoView hg38]
Mapping of homologs : NCBISNCAIP [Mapview hg19]  SNCAIP [Mapview hg38]
OMIM168600   603779   
Gene and transcription
Genbank (Entrez)AB110788 AB110789 AB110790 AB110791 AB110792
RefSeq transcript (Entrez)NM_001242935 NM_001308100 NM_001308105 NM_001308106 NM_001308107 NM_001308108 NM_001308109 NM_005460
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SNCAIP
Cluster EST : UnigeneHs.426463 [ NCBI ]
CGAP (NCI)Hs.426463
Alternative Splicing GalleryENSG00000064692
Gene ExpressionSNCAIP [ NCBI-GEO ]   SNCAIP [ EBI - ARRAY_EXPRESS ]   SNCAIP [ SEEK ]   SNCAIP [ MEM ]
Gene Expression Viewer (FireBrowse)SNCAIP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9627
GTEX Portal (Tissue expression)SNCAIP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6H5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6H5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6H5
Splice isoforms : SwissVarQ9Y6H5
PhosPhoSitePlusQ9Y6H5
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    SNCAIP_SNCA-bd   
Domain families : Pfam (Sanger)Ank_2 (PF12796)    SNCAIP_SNCA_bd (PF16700)   
Domain families : Pfam (NCBI)pfam12796    pfam16700   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)SNCAIP
DMDM Disease mutations9627
Blocks (Seattle)SNCAIP
PDB (SRS)2KES   
PDB (PDBSum)2KES   
PDB (IMB)2KES   
PDB (RSDB)2KES   
Structural Biology KnowledgeBase2KES   
SCOP (Structural Classification of Proteins)2KES   
CATH (Classification of proteins structures)2KES   
SuperfamilyQ9Y6H5
Human Protein AtlasENSG00000064692
Peptide AtlasQ9Y6H5
HPRD04804
IPIIPI00002293   IPI00956102   IPI00385910   IPI00967042   IPI00956081   IPI00438113   IPI01012431   IPI00651750   IPI00922614   IPI00438110   IPI00968207   IPI00438111   IPI00438108   IPI00966852   IPI00964381   IPI00966097   IPI00965464   IPI00967407   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6H5
IntAct (EBI)Q9Y6H5
FunCoupENSG00000064692
BioGRIDSNCAIP
STRING (EMBL)SNCAIP
ZODIACSNCAIP
Ontologies - Pathways
QuickGOQ9Y6H5
Ontology : AmiGOP-body  protein binding  nucleoplasm  cytoplasm  cytosol  synaptic vesicle  cell death  ubiquitin protein ligase binding  dopamine metabolic process  presynaptic membrane  identical protein binding  neuronal cell body  cellular protein metabolic process  regulation of neurotransmitter secretion  regulation of inclusion body assembly  
Ontology : EGO-EBIP-body  protein binding  nucleoplasm  cytoplasm  cytosol  synaptic vesicle  cell death  ubiquitin protein ligase binding  dopamine metabolic process  presynaptic membrane  identical protein binding  neuronal cell body  cellular protein metabolic process  regulation of neurotransmitter secretion  regulation of inclusion body assembly  
Pathways : BIOCARTARole of Parkin in the Ubiquitin-Proteasomal Pathway [Genes]   
Pathways : KEGGParkinson's disease   
NDEx NetworkSNCAIP
Atlas of Cancer Signalling NetworkSNCAIP
Wikipedia pathwaysSNCAIP
Orthology - Evolution
OrthoDB9627
GeneTree (enSembl)ENSG00000064692
Phylogenetic Trees/Animal Genes : TreeFamSNCAIP
HOVERGENQ9Y6H5
HOGENOMQ9Y6H5
Homologs : HomoloGeneSNCAIP
Homology/Alignments : Family Browser (UCSC)SNCAIP
Gene fusions - Rearrangements
Fusion : MitelmanSNX24/SNCAIP [5q23.2/5q23.2]  [t(5;5)(q23;q23)]  
Fusion: TCGASNX24 5q23.2 SNCAIP 5q23.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSNCAIP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SNCAIP
dbVarSNCAIP
ClinVarSNCAIP
1000_GenomesSNCAIP 
Exome Variant ServerSNCAIP
ExAC (Exome Aggregation Consortium)SNCAIP (select the gene name)
Genetic variants : HAPMAP9627
Genomic Variants (DGV)SNCAIP [DGVbeta]
DECIPHERSNCAIP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSNCAIP 
Mutations
ICGC Data PortalSNCAIP 
TCGA Data PortalSNCAIP 
Broad Tumor PortalSNCAIP
OASIS PortalSNCAIP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSNCAIP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSNCAIP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SNCAIP
DgiDB (Drug Gene Interaction Database)SNCAIP
DoCM (Curated mutations)SNCAIP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SNCAIP (select a term)
intoGenSNCAIP
Cancer3DSNCAIP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM168600    603779   
Orphanet
MedgenSNCAIP
Genetic Testing Registry SNCAIP
NextProtQ9Y6H5 [Medical]
TSGene9627
GENETestsSNCAIP
Target ValidationSNCAIP
Huge Navigator SNCAIP [HugePedia]
snp3D : Map Gene to Disease9627
BioCentury BCIQSNCAIP
ClinGenSNCAIP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9627
Chemical/Pharm GKB GenePA35987
Clinical trialSNCAIP
Miscellaneous
canSAR (ICR)SNCAIP (select the gene name)
Probes
Litterature
PubMed89 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSNCAIP
EVEXSNCAIP
GoPubMedSNCAIP
iHOPSNCAIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:56:40 CEST 2017

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