SNF1LK (SNF1-like kinase)

Identity

Other names	MSK
	SIK
	SIK1
HGNC	SNF1LK
Location	21q22.3
Location_base_pair	Starts at 43658827 and ends at 43671430 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	SNF1LK   11142
Entrez_Gene	SNF1LK  150094  SNF1-like kinase
	Cards
GeneCards	SNF1LK
Ensembl	ENSG00000142178 [Gene_View]  SNF1LK [Vega]
Genatlas	SNF1LK
	Genomic and cartography
GoldenPath	SNF1LK  -  21q22.3   chr21:43658827-43671430 -  21q22.3   [Description]    (hg18-March_2006)
Ensembl	SNF1LK - 21q22.3 [CytoView]
NCBI	Mapview
OMIM	605705 Disease map [OMIM]
HomoloGene	SNF1LK
	Gene and transcription
Genbank	AB047786 [ ENTREZ ]
Genbank	AI073528 [ ENTREZ ]
Genbank	AK131076 [ ENTREZ ]
Genbank	BC038504 [ ENTREZ ]
Genbank	BM840872 [ ENTREZ ]
RefSeq	NM_173354 [ SRS ]    NM_173354 [ ENTREZ ]
RefSeq	AC_000064 [ SRS ]    AC_000064 [ ENTREZ ]
RefSeq	AC_000153 [ SRS ]    AC_000153 [ ENTREZ ]
RefSeq	NC_000021 [ SRS ]    NC_000021 [ ENTREZ ]
RefSeq	NT_011515 [ SRS ]    NT_011515 [ ENTREZ ]
RefSeq	NW_001838716 [ SRS ]    NW_001838716 [ ENTREZ ]
RefSeq	NW_927384 [ SRS ]    NW_927384 [ ENTREZ ]
CCDS	SNF1LK CCDS - NCBI
AceView	SNF1LK AceView - NCBI
Unigene	Hs.700423 [ SRS ]    Hs.700423 [ NCBI ]
Fast-db	3714 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P57059 [ SRS]    P57059 [ EXPASY ]     P57059 [ INTERPRO ]     P57059 [ UNIPROT ] P57059 [ VarSplice FASTA ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Prosite	PS50030 UBA [ SRS ]    PS50030 UBA [ Expasy ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR017442 Se/Thr_pkinase-rel [ SRS ]    IPR017442 Se/Thr_pkinase-rel [ EBI ]
Interpro	IPR017090 Ser/Thr_prot_kinase_SNF1-like [ SRS ]    IPR017090 Ser/Thr_prot_kinase_SNF1-like [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
Interpro	IPR015738 Snf1_like_pk [ SRS ]    IPR015738 Snf1_like_pk [ EBI ]
Interpro	IPR015940 UBA/transl_elong_EF1B_N_euk [ SRS ]    IPR015940 UBA/transl_elong_EF1B_N_euk [ EBI ]
CluSTr	P57059
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Smart	SM00220 S_TKc [EMBL]
Smart	SM00165 UBA [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	P57059 SN1L1_HUMAN [ Domain structure ]   P57059 SN1L1_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P57059
HPRD	09301
	Protein Interaction databases
DIP	P57059
IntAct	P57059
	Polymorphism : SNP, mutations, diseases
OMIM	605705    [ map ]
GENETests	605705
SNP	SNF1LK [dbSNP-NCBI]
SNP	NM_173354 [SNP-NCI]
SNP	SNF1LK [GeneSNPs - Utah]  SNF1LK] [HGBASE - SRS]
HAPMAP	SNF1LK [HAPMAP]
COSMIC	SNF1LK [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	SNF1LK
Genetic Association	SNF1LK
CDC HuGE	SNF1LK
	General knowledge
Family Browser	SNF1LK [UCSC Family Browser]
SOURCE	NM_173354
SMD	Hs.700423
SAGE	Hs.700423
Enzyme	2.7.11.1 [ Enzyme-Expasy ]   2.7.11.1 [ Enzyme-SRS ]   2.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	magnesium ion binding [Amigo]  magnesium ion binding
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	ATP binding [Amigo]  ATP binding
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	cytoplasm [Amigo]  cytoplasm
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	cell cycle [Amigo]  cell cycle
GO	protein kinase cascade [Amigo]  protein kinase cascade
GO	protein kinase cascade [Amigo]  protein kinase cascade
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	regulation of mitotic cell cycle [Amigo]  regulation of mitotic cell cycle
GO	transferase activity [Amigo]  transferase activity
GO	regulation of cell differentiation [Amigo]  regulation of cell differentiation
PubGene	SNF1LK
TreeFam	SNF1LK
CTD	150094 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	SNF1LK Related clones (RZPD - Berlin)
	PubMed
PubMed	8 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:12:53 2008