Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SNRPE (small nuclear ribonucleoprotein polypeptide E)

Identity

Alias_symbol (synonym)Sm-E
Other aliasHYPT11
SME
snRNP-E
HGNC (Hugo) SNRPE
LocusID (NCBI) 6635
Atlas_Id 50574
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 203861585 and ends at 203871152 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		PRR11 (17q22) / SNRPE (1q32.1)SNRPE (1q32.1) / PRTFDC1 (10p12.1)SNRPE (1q32.1) / SETBP1 (18q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SNRPE   11161
Cards
Entrez_Gene (NCBI)SNRPE  6635  small nuclear ribonucleoprotein polypeptide E
AliasesHYPT11; SME; Sm-E; snRNP-E
GeneCards (Weizmann)SNRPE
Ensembl hg19 (Hinxton)ENSG00000182004 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182004 [Gene_View]  chr1:203861585-203871152 [Contig_View]  SNRPE [Vega]
ICGC DataPortalENSG00000182004
TCGA cBioPortalSNRPE
AceView (NCBI)SNRPE
Genatlas (Paris)SNRPE
WikiGenes6635
SOURCE (Princeton)SNRPE
Genetics Home Reference (NIH)SNRPE
Genomic and cartography
GoldenPath hg38 (UCSC)SNRPE  -     chr1:203861585-203871152 +  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SNRPE  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblSNRPE - 1q32.1 [CytoView hg19]  SNRPE - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBISNRPE [Mapview hg19]  SNRPE [Mapview hg38]
OMIM128260   615059   
Gene and transcription
Genbank (Entrez)AA344740 AI263891 AK307255 AK309140 AK312130
RefSeq transcript (Entrez)NM_001304464 NM_001328637 NM_001328638 NM_003094
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SNRPE
Cluster EST : UnigeneHs.654418 [ NCBI ]
CGAP (NCI)Hs.654418
Alternative Splicing GalleryENSG00000182004
Gene ExpressionSNRPE [ NCBI-GEO ]   SNRPE [ EBI - ARRAY_EXPRESS ]   SNRPE [ SEEK ]   SNRPE [ MEM ]
Gene Expression Viewer (FireBrowse)SNRPE [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6635
GTEX Portal (Tissue expression)SNRPE
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62304   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62304  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62304
Splice isoforms : SwissVarP62304
PhosPhoSitePlusP62304
Domains : Interpro (EBI)LSM_dom    LSM_dom_euk/arc    snRNP-E   
Domain families : Pfam (Sanger)LSM (PF01423)   
Domain families : Pfam (NCBI)pfam01423   
Domain families : Smart (EMBL)Sm (SM00651)  
Conserved Domain (NCBI)SNRPE
DMDM Disease mutations6635
Blocks (Seattle)SNRPE
PDB (SRS)3CW1    3JCR    3PGW    3S6N    4F7U    4PJO    4V98    4WZJ   
PDB (PDBSum)3CW1    3JCR    3PGW    3S6N    4F7U    4PJO    4V98    4WZJ   
PDB (IMB)3CW1    3JCR    3PGW    3S6N    4F7U    4PJO    4V98    4WZJ   
PDB (RSDB)3CW1    3JCR    3PGW    3S6N    4F7U    4PJO    4V98    4WZJ   
Structural Biology KnowledgeBase3CW1    3JCR    3PGW    3S6N    4F7U    4PJO    4V98    4WZJ   
SCOP (Structural Classification of Proteins)3CW1    3JCR    3PGW    3S6N    4F7U    4PJO    4V98    4WZJ   
CATH (Classification of proteins structures)3CW1    3JCR    3PGW    3S6N    4F7U    4PJO    4V98    4WZJ   
SuperfamilyP62304
Human Protein AtlasENSG00000182004
Peptide AtlasP62304
HPRD00548
IPIIPI00029266   IPI00647942   
Protein Interaction databases
DIP (DOE-UCLA)P62304
IntAct (EBI)P62304
FunCoupENSG00000182004
BioGRIDSNRPE
STRING (EMBL)SNRPE
ZODIACSNRPE
Ontologies - Pathways
QuickGOP62304
Ontology : AmiGOspliceosomal complex assembly  spliceosomal snRNP assembly  spliceosomal snRNP assembly  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  protein binding  nucleus  nucleoplasm  spliceosomal complex  U7 snRNP  U1 snRNP  U4 snRNP  U12-type spliceosomal complex  telomerase holoenzyme complex  cytosol  cytosol  termination of RNA polymerase II transcription  histone mRNA metabolic process  small nuclear ribonucleoprotein complex  methylosome  pICln-Sm protein complex  SMN-Sm protein complex  hair cycle  nuclear import  extracellular exosome  catalytic step 2 spliceosome  
Ontology : EGO-EBIspliceosomal complex assembly  spliceosomal snRNP assembly  spliceosomal snRNP assembly  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  protein binding  nucleus  nucleoplasm  spliceosomal complex  U7 snRNP  U1 snRNP  U4 snRNP  U12-type spliceosomal complex  telomerase holoenzyme complex  cytosol  cytosol  termination of RNA polymerase II transcription  histone mRNA metabolic process  small nuclear ribonucleoprotein complex  methylosome  pICln-Sm protein complex  SMN-Sm protein complex  hair cycle  nuclear import  extracellular exosome  catalytic step 2 spliceosome  
Pathways : BIOCARTASpliceosomal Assembly [Genes]   
Pathways : KEGGSpliceosome   
NDEx NetworkSNRPE
Atlas of Cancer Signalling NetworkSNRPE
Wikipedia pathwaysSNRPE
Orthology - Evolution
OrthoDB6635
GeneTree (enSembl)ENSG00000182004
Phylogenetic Trees/Animal Genes : TreeFamSNRPE
HOVERGENP62304
HOGENOMP62304
Homologs : HomoloGeneSNRPE
Homology/Alignments : Family Browser (UCSC)SNRPE
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSNRPE [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SNRPE
dbVarSNRPE
ClinVarSNRPE
1000_GenomesSNRPE 
Exome Variant ServerSNRPE
ExAC (Exome Aggregation Consortium)SNRPE (select the gene name)
Genetic variants : HAPMAP6635
Genomic Variants (DGV)SNRPE [DGVbeta]
DECIPHERSNRPE [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSNRPE 
Mutations
ICGC Data PortalSNRPE 
TCGA Data PortalSNRPE 
Broad Tumor PortalSNRPE
OASIS PortalSNRPE [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSNRPE  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSNRPE
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SNRPE
DgiDB (Drug Gene Interaction Database)SNRPE
DoCM (Curated mutations)SNRPE (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SNRPE (select a term)
intoGenSNRPE
Cancer3DSNRPE(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM128260    615059   
Orphanet10760   
MedgenSNRPE
Genetic Testing Registry SNRPE
NextProtP62304 [Medical]
TSGene6635
GENETestsSNRPE
Target ValidationSNRPE
Huge Navigator SNRPE [HugePedia]
snp3D : Map Gene to Disease6635
BioCentury BCIQSNRPE
ClinGenSNRPE
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6635
Chemical/Pharm GKB GenePA36002
Clinical trialSNRPE
Miscellaneous
canSAR (ICR)SNRPE (select the gene name)
Probes
Litterature
PubMed71 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSNRPE
EVEXSNRPE
GoPubMedSNRPE
iHOPSNRPE
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:56:46 CEST 2017
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