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SNTB2 (syntrophin beta 2)

Identity

Alias_namesSNT2B2
SNTL
D16S2531E
syntrophin
Alias_symbol (synonym)EST25263
SNT3
Other alias
HGNC (Hugo) SNTB2
LocusID (NCBI) 6645
Atlas_Id 54650
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 69187147 and ends at 69309052 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NFAT5 (16q22.1) / SNTB2 (16q22.1)SNTB2 (16q22.1) / CHST4 (16q22.2)SNTB2 (16q22.1) / CTDSP1 (2q35)
SNTB2 (16q22.1) / IL34 (16q22.1)SNTB2 (16q22.1) / RBM45 (rq31.)<.TD>SNTB2 (16q22.1) / TANGO6 (16q22.1)
SNTB2 (16q22.1) / UTP4 (16q22.1)SNTB2 (16q22.1) / VPS4A (16q22.1)SNTB2 (16q22.1) / ZCRB1 (12q12)
ZNF326 (1p22.2) / SNTB2 (16q22.1)SNTB2 16q22.1 / CHST4 16q22.2SNTB2 16q22.1 / CIRH1A 16q22.1
SNTB2 16q22.1 TMCO7

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SNTB2   11169
Cards
Entrez_Gene (NCBI)SNTB2  6645  syntrophin beta 2
AliasesD16S2531E; EST25263; SNT2B2; SNT3; 
SNTL
GeneCards (Weizmann)SNTB2
Ensembl hg19 (Hinxton)ENSG00000168807 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168807 [Gene_View]  chr16:69187147-69309052 [Contig_View]  SNTB2 [Vega]
ICGC DataPortalENSG00000168807
TCGA cBioPortalSNTB2
AceView (NCBI)SNTB2
Genatlas (Paris)SNTB2
WikiGenes6645
SOURCE (Princeton)SNTB2
Genetics Home Reference (NIH)SNTB2
Genomic and cartography
GoldenPath hg38 (UCSC)SNTB2  -     chr16:69187147-69309052 +  16q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SNTB2  -     16q22.1   [Description]    (hg19-Feb_2009)
EnsemblSNTB2 - 16q22.1 [CytoView hg19]  SNTB2 - 16q22.1 [CytoView hg38]
Mapping of homologs : NCBISNTB2 [Mapview hg19]  SNTB2 [Mapview hg38]
OMIM600027   
Gene and transcription
Genbank (Entrez)AF243385 BC031058 BC035134 BC036429 BC048215
RefSeq transcript (Entrez)NM_006750 NM_130845
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SNTB2
Cluster EST : UnigeneHs.461117 [ NCBI ]
CGAP (NCI)Hs.461117
Alternative Splicing GalleryENSG00000168807
Gene ExpressionSNTB2 [ NCBI-GEO ]   SNTB2 [ EBI - ARRAY_EXPRESS ]   SNTB2 [ SEEK ]   SNTB2 [ MEM ]
Gene Expression Viewer (FireBrowse)SNTB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6645
GTEX Portal (Tissue expression)SNTB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13425   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13425  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13425
Splice isoforms : SwissVarQ13425
PhosPhoSitePlusQ13425
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)PDZ    PH_dom-like    PH_domain    SNTB2    Syntrophin   
Domain families : Pfam (Sanger)PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam00595   
Domain families : Smart (EMBL)PDZ (SM00228)  PH (SM00233)  
Conserved Domain (NCBI)SNTB2
DMDM Disease mutations6645
Blocks (Seattle)SNTB2
PDB (SRS)2VRF   
PDB (PDBSum)2VRF   
PDB (IMB)2VRF   
PDB (RSDB)2VRF   
Structural Biology KnowledgeBase2VRF   
SCOP (Structural Classification of Proteins)2VRF   
CATH (Classification of proteins structures)2VRF   
SuperfamilyQ13425
Human Protein AtlasENSG00000168807
Peptide AtlasQ13425
HPRD02491
IPIIPI00009505   IPI00216631   IPI00984268   IPI00977680   IPI00974473   IPI00984748   IPI00983597   
Protein Interaction databases
DIP (DOE-UCLA)Q13425
IntAct (EBI)Q13425
FunCoupENSG00000168807
BioGRIDSNTB2
STRING (EMBL)SNTB2
ZODIACSNTB2
Ontologies - Pathways
QuickGOQ13425
Ontology : AmiGORNA binding  actin binding  structural molecule activity  protein binding  calmodulin binding  cytoplasm  microtubule  focal adhesion  dystrophin-associated glycoprotein complex  membrane  transport vesicle membrane  protein complex  synapse  extracellular exosome  
Ontology : EGO-EBIRNA binding  actin binding  structural molecule activity  protein binding  calmodulin binding  cytoplasm  microtubule  focal adhesion  dystrophin-associated glycoprotein complex  membrane  transport vesicle membrane  protein complex  synapse  extracellular exosome  
NDEx NetworkSNTB2
Atlas of Cancer Signalling NetworkSNTB2
Wikipedia pathwaysSNTB2
Orthology - Evolution
OrthoDB6645
GeneTree (enSembl)ENSG00000168807
Phylogenetic Trees/Animal Genes : TreeFamSNTB2
HOVERGENQ13425
HOGENOMQ13425
Homologs : HomoloGeneSNTB2
Homology/Alignments : Family Browser (UCSC)SNTB2
Gene fusions - Rearrangements
Fusion : MitelmanNFAT5/SNTB2 [16q22.1/16q22.1]  [dup(16)(q22q22)]  
Fusion : MitelmanSNTB2/CHST4 [16q22.1/16q22.2]  [t(16;16)(q22;q22)]  
Fusion : MitelmanSNTB2/CIRH1A [16q22.1/16q22.1]  [t(16;16)(q22;q22)]  
Fusion : MitelmanSNTB2/TANGO6 [16q22.1/16q22.1]  [t(16;16)(q22;q22)]  
Fusion : MitelmanSNTB2/VPS4A [16q22.1/16q22.1]  [t(16;16)(q22;q22)]  
Fusion: TCGASNTB2 16q22.1 CHST4 16q22.2 BRCA
Fusion: TCGASNTB2 16q22.1 CIRH1A 16q22.1 KIRC LUAD
Fusion: TCGASNTB2 16q22.1 TMCO7 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSNTB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SNTB2
dbVarSNTB2
ClinVarSNTB2
1000_GenomesSNTB2 
Exome Variant ServerSNTB2
ExAC (Exome Aggregation Consortium)SNTB2 (select the gene name)
Genetic variants : HAPMAP6645
Genomic Variants (DGV)SNTB2 [DGVbeta]
DECIPHERSNTB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSNTB2 
Mutations
ICGC Data PortalSNTB2 
TCGA Data PortalSNTB2 
Broad Tumor PortalSNTB2
OASIS PortalSNTB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSNTB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSNTB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SNTB2
DgiDB (Drug Gene Interaction Database)SNTB2
DoCM (Curated mutations)SNTB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SNTB2 (select a term)
intoGenSNTB2
Cancer3DSNTB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600027   
Orphanet
MedgenSNTB2
Genetic Testing Registry SNTB2
NextProtQ13425 [Medical]
TSGene6645
GENETestsSNTB2
Target ValidationSNTB2
Huge Navigator SNTB2 [HugePedia]
snp3D : Map Gene to Disease6645
BioCentury BCIQSNTB2
ClinGenSNTB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6645
Chemical/Pharm GKB GenePA36009
Clinical trialSNTB2
Miscellaneous
canSAR (ICR)SNTB2 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSNTB2
EVEXSNTB2
GoPubMedSNTB2
iHOPSNTB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:32:21 CEST 2017

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