Fusion genes
(updated 2016) | EIF4G1 (3q27.1) / SNW1 (14q24.3) | IGF2 (11p15.5) / SNW1 (14q24.3) | LARGE (22q12.3) / SNW1 (14q24.3) |
| |
MYO1C (17p13.3) / SNW1 (14q24.3) | NDRG1 (8q24.22) / SNW1 (14q24.3) | RPL8 (8q24.3) / SNW1 (14q24.3) |
| |
SNW1 (14q24.3) / SNW1 (14q24.3) | EIF4G1 3q27.1 / SNW1 14q24.3 | IGF2 11p15.5 / SNW1 14q24.3 |
| |
LARGE 22q12.3 / SNW1 14q24.3 | NDRG1 8q24.22 / SNW1 14q24.3 | RPL8 8q24.3 / SNW1 14q24.3 |
| |
| Nomenclature |
|---|
| HGNC (Hugo) | SNW1 16696 |
| Cards |
|---|
| Entrez_Gene (NCBI) | SNW1 22938 SNW domain containing 1 |
| Aliases | Bx42; NCOA-62; PRPF45; Prp45; |
| SKIIP; SKIP |
| GeneCards (Weizmann) | SNW1 |
| Ensembl hg19 (Hinxton) | ENSG00000100603 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000100603 [Gene_View] chr14:77717601-77761154 [Contig_View] SNW1 [Vega] |
| ICGC DataPortal | ENSG00000100603 |
| TCGA cBioPortal | SNW1 |
| AceView (NCBI) | SNW1 |
| Genatlas (Paris) | SNW1 |
| WikiGenes | 22938 |
| SOURCE (Princeton) | SNW1 |
| Genetics Home Reference (NIH) | SNW1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | SNW1 - chr14:77717601-77761154 - 14q24.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | SNW1 - 14q24.3 [Description] (hg19-Feb_2009) |
| Ensembl | SNW1 - 14q24.3 [CytoView hg19] SNW1 - 14q24.3 [CytoView hg38] |
| Mapping of homologs : NCBI | SNW1 [Mapview hg19] SNW1 [Mapview hg38] |
| OMIM | 603055 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF045184 AK292274 AK293619 AK302246 AK316087 |
| RefSeq transcript (Entrez) | NM_001318844 NM_012245 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | SNW1 |
| Cluster EST : Unigene | Hs.445498 [ NCBI ] |
| CGAP (NCI) | Hs.445498 |
| Alternative Splicing Gallery | ENSG00000100603 |
| Gene Expression | SNW1 [ NCBI-GEO ] SNW1 [ EBI - ARRAY_EXPRESS ]
SNW1 [ SEEK ] SNW1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | SNW1 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevisible | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 22938 |
| GTEX Portal (Tissue expression) | SNW1 |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q13573 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q13573 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q13573 |
| Splice isoforms : SwissVar | Q13573 |
| PhosPhoSitePlus | Q13573 |
| Domains : Interpro (EBI) | SKI-int_prot_SKIP SKI-int_prot_SKIP_SNW-dom |
| Domain families : Pfam (Sanger) | SKIP_SNW (PF02731) |
| Domain families : Pfam (NCBI) | pfam02731 |
| Conserved Domain (NCBI) | SNW1 |
| DMDM Disease mutations | 22938 |
| Blocks (Seattle) | SNW1 |
| Superfamily | Q13573 |
| Human Protein Atlas | ENSG00000100603 |
| Peptide Atlas | Q13573 |
| HPRD | 04340 |
| IPI | IPI00013830 IPI00943237 IPI00910816 IPI01025618 IPI01025271 IPI01025390 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q13573 |
| IntAct (EBI) | Q13573 |
| FunCoup | ENSG00000100603 |
| BioGRID | SNW1 |
| STRING (EMBL) | SNW1 |
| ZODIAC | SNW1 |
| Ontologies - Pathways |
|---|
| QuickGO | Q13573 |
| Ontology : AmiGO | negative regulation of transcription from RNA polymerase II promoter generation of catalytic spliceosome for second transesterification step mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome transcription coactivator activity transcription corepressor activity RNA binding Notch binding protein binding nucleus nucleoplasm nucleoplasm spliceosomal complex regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter Notch signaling pathway cyclin/CDK positive transcription elongation factor complex viral process nuclear matrix nuclear body nuclear speck enzyme binding positive regulation of transforming growth factor beta receptor signaling pathway nuclear hormone receptor binding intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator vitamin D receptor binding retinoic acid receptor binding positive regulation by host of viral transcription positive regulation by host of viral transcription negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter SMAD binding positive regulation of mRNA splicing, via spliceosome retinoic acid receptor signaling pathway regulation of retinoic acid receptor signaling pathway androgen receptor binding positive regulation of neurogenesis positive regulation of histone H3-K4 methylation regulation of vitamin D receptor signaling pathway positive regulation of vitamin D receptor signaling pathway catalytic step 2 spliceosome post-mRNA release spliceosomal complex SMAD3-SMAD4 protein complex cellular response to retinoic acid |
| Ontology : EGO-EBI | negative regulation of transcription from RNA polymerase II promoter generation of catalytic spliceosome for second transesterification step mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome transcription coactivator activity transcription corepressor activity RNA binding Notch binding protein binding nucleus nucleoplasm nucleoplasm spliceosomal complex regulation of transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter Notch signaling pathway cyclin/CDK positive transcription elongation factor complex viral process nuclear matrix nuclear body nuclear speck enzyme binding positive regulation of transforming growth factor beta receptor signaling pathway nuclear hormone receptor binding intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator vitamin D receptor binding retinoic acid receptor binding positive regulation by host of viral transcription positive regulation by host of viral transcription negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter SMAD binding positive regulation of mRNA splicing, via spliceosome retinoic acid receptor signaling pathway regulation of retinoic acid receptor signaling pathway androgen receptor binding positive regulation of neurogenesis positive regulation of histone H3-K4 methylation regulation of vitamin D receptor signaling pathway positive regulation of vitamin D receptor signaling pathway catalytic step 2 spliceosome post-mRNA release spliceosomal complex SMAD3-SMAD4 protein complex cellular response to retinoic acid |
| Pathways : KEGG | Spliceosome Notch signaling pathway Epstein-Barr virus infection Viral carcinogenesis |
| NDEx Network | SNW1 |
| Atlas of Cancer Signalling Network | SNW1 |
| Wikipedia pathways | SNW1 |
| Orthology - Evolution |
|---|
| OrthoDB | 22938 |
| GeneTree (enSembl) | ENSG00000100603 |
| Phylogenetic Trees/Animal Genes : TreeFam | SNW1 |
| HOVERGEN | Q13573 |
| HOGENOM | Q13573 |
| Homologs : HomoloGene | SNW1 |
| Homology/Alignments : Family Browser (UCSC) | SNW1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | EIF4G1/SNW1 [3q27.1/14q24.3] [t(3;14)(q27;q24)] |
| Fusion : Mitelman | IGF2/SNW1 [11p15.5/14q24.3] [t(11;14)(p15;q24)] |
| Fusion : Mitelman | LARGE/SNW1 [22q12.3/14q24.3] [t(14;22)(q24;q12)] |
| Fusion : Mitelman | NDRG1/SNW1 [8q24.22/14q24.3] [t(8;14)(q24;q24)] |
| Fusion : Mitelman | RPL8/SNW1 [8q24.3/14q24.3] [t(8;14)(q24;q24)] |
| Fusion: TCGA | EIF4G1 3q27.1 SNW1 14q24.3 LUAD |
| Fusion: TCGA | IGF2 11p15.5 SNW1 14q24.3 THCA |
| Fusion: TCGA | LARGE 22q12.3 SNW1 14q24.3 BRCA |
| Fusion: TCGA | NDRG1 8q24.22 SNW1 14q24.3 BLCA |
| Fusion: TCGA | RPL8 8q24.3 SNW1 14q24.3 BRCA |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | SNW1 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | SNW1 |
| dbVar | SNW1 |
| ClinVar | SNW1 |
| 1000_Genomes | SNW1 |
| Exome Variant Server | SNW1 |
| ExAC (Exome Aggregation Consortium) | SNW1 (select the gene name) |
| Genetic variants : HAPMAP | 22938 |
| Genomic Variants (DGV) | SNW1 [DGVbeta] |
| DECIPHER | SNW1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | SNW1 |
| Mutations |
|---|
| ICGC Data Portal | SNW1 |
| TCGA Data Portal | SNW1 |
| Broad Tumor Portal | SNW1 |
| OASIS Portal | SNW1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | SNW1 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | SNW1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search SNW1 |
| DgiDB (Drug Gene Interaction Database) | SNW1 |
| DoCM (Curated mutations) | SNW1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | SNW1 (select a term) |
| intoGen | SNW1 |
| Cancer3D | SNW1(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 603055 |
| Orphanet | |
| Medgen | SNW1 |
| Genetic Testing Registry | SNW1
|
| NextProt | Q13573 [Medical] |
| TSGene | 22938 |
| GENETests | SNW1 |
| Target Validation | SNW1 |
| Huge Navigator |
SNW1 [HugePedia] |
| snp3D : Map Gene to Disease | 22938 |
| BioCentury BCIQ | SNW1 |
| ClinGen | SNW1 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 22938 |
| Chemical/Pharm GKB Gene | PA134883977 |
| Clinical trial | SNW1 |
| Miscellaneous |
|---|
| canSAR (ICR) | SNW1 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 95 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | SNW1 |
| EVEX | SNW1 |
| GoPubMed | SNW1 |
| iHOP | SNW1 |
