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SNX10 (sorting nexin 10)

Identity

Other aliasOPTB8
HGNC (Hugo) SNX10
LocusID (NCBI) 29887
Atlas_Id 54651
Location 7p15.2  [Link to chromosome band 7p15]
Location_base_pair Starts at 26331515 and ends at 26413949 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HDAC9 (7p21.1) / SNX10 (7p15.2)RASSF3 (12q14.2) / SNX10 (7p15.2)SKAP2 (7p15.2) / SNX10 (7p15.2)
SNX10 (7p15.2) / SEMA4A (1q22)HDAC9 7p21.1 / SNX10 7p15.2RASSF3 12q14.2 / SNX10 7p15.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SNX10   14974
Cards
Entrez_Gene (NCBI)SNX10  29887  sorting nexin 10
AliasesOPTB8
GeneCards (Weizmann)SNX10
Ensembl hg19 (Hinxton)ENSG00000086300 [Gene_View]  chr7:26331515-26413949 [Contig_View]  SNX10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000086300 [Gene_View]  chr7:26331515-26413949 [Contig_View]  SNX10 [Vega]
ICGC DataPortalENSG00000086300
TCGA cBioPortalSNX10
AceView (NCBI)SNX10
Genatlas (Paris)SNX10
WikiGenes29887
SOURCE (Princeton)SNX10
Genetics Home Reference (NIH)SNX10
Genomic and cartography
GoldenPath hg19 (UCSC)SNX10  -     chr7:26331515-26413949 +  7p15.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SNX10  -     7p15.2   [Description]    (hg38-Dec_2013)
EnsemblSNX10 - 7p15.2 [CytoView hg19]  SNX10 - 7p15.2 [CytoView hg38]
Mapping of homologs : NCBISNX10 [Mapview hg19]  SNX10 [Mapview hg38]
OMIM614780   615085   
Gene and transcription
Genbank (Entrez)AF121860 AK296142 AK307905 AK309162 AK311256
RefSeq transcript (Entrez)NM_001199835 NM_001199837 NM_001199838 NM_001318198 NM_001318199 NM_013322
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_033902 NT_007819 NW_004929329
Consensus coding sequences : CCDS (NCBI)SNX10
Cluster EST : UnigeneHs.741316 [ NCBI ]
CGAP (NCI)Hs.741316
Alternative Splicing GalleryENSG00000086300
Gene ExpressionSNX10 [ NCBI-GEO ]   SNX10 [ EBI - ARRAY_EXPRESS ]   SNX10 [ SEEK ]   SNX10 [ MEM ]
Gene Expression Viewer (FireBrowse)SNX10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29887
GTEX Portal (Tissue expression)SNX10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5X0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5X0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5X0
Splice isoforms : SwissVarQ9Y5X0
PhosPhoSitePlusQ9Y5X0
Domaine pattern : Prosite (Expaxy)PX (PS50195)   
Domains : Interpro (EBI)Phox   
Domain families : Pfam (Sanger)PX (PF00787)   
Domain families : Pfam (NCBI)pfam00787   
Domain families : Smart (EMBL)PX (SM00312)  
Conserved Domain (NCBI)SNX10
DMDM Disease mutations29887
Blocks (Seattle)SNX10
PDB (SRS)4ON3    4PZG   
PDB (PDBSum)4ON3    4PZG   
PDB (IMB)4ON3    4PZG   
PDB (RSDB)4ON3    4PZG   
Structural Biology KnowledgeBase4ON3    4PZG   
SCOP (Structural Classification of Proteins)4ON3    4PZG   
CATH (Classification of proteins structures)4ON3    4PZG   
SuperfamilyQ9Y5X0
Human Protein AtlasENSG00000086300
Peptide AtlasQ9Y5X0
HPRD15409
IPIIPI00916501   IPI00001881   IPI00916251   IPI00916538   IPI00916701   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5X0
IntAct (EBI)Q9Y5X0
FunCoupENSG00000086300
BioGRIDSNX10
STRING (EMBL)SNX10
ZODIACSNX10
Ontologies - Pathways
QuickGOQ9Y5X0
Ontology : AmiGOprotein binding  1-phosphatidylinositol binding  nucleus  endoplasmic reticulum  centrosome  endocytosis  endosome organization  protein transport  vesicle organization  osteoclast differentiation  extrinsic component of endosome membrane  cilium assembly  ATPase binding  protein localization to cilium  protein localization to centrosome  
Ontology : EGO-EBIprotein binding  1-phosphatidylinositol binding  nucleus  endoplasmic reticulum  centrosome  endocytosis  endosome organization  protein transport  vesicle organization  osteoclast differentiation  extrinsic component of endosome membrane  cilium assembly  ATPase binding  protein localization to cilium  protein localization to centrosome  
NDEx NetworkSNX10
Atlas of Cancer Signalling NetworkSNX10
Wikipedia pathwaysSNX10
Orthology - Evolution
OrthoDB29887
GeneTree (enSembl)ENSG00000086300
Phylogenetic Trees/Animal Genes : TreeFamSNX10
HOVERGENQ9Y5X0
HOGENOMQ9Y5X0
Homologs : HomoloGeneSNX10
Homology/Alignments : Family Browser (UCSC)SNX10
Gene fusions - Rearrangements
Fusion : MitelmanHDAC9/SNX10 [7p21.1/7p15.2]  [t(7;7)(p15;p21)]  
Fusion : MitelmanRASSF3/SNX10 [12q14.2/7p15.2]  [t(7;12)(p15;q14)]  
Fusion : MitelmanSKAP2/SNX10 [7p15.2/7p15.2]  [t(7;7)(p15;p15)]  
Fusion: TCGAHDAC9 7p21.1 SNX10 7p15.2 LUAD
Fusion: TCGARASSF3 12q14.2 SNX10 7p15.2 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSNX10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SNX10
dbVarSNX10
ClinVarSNX10
1000_GenomesSNX10 
Exome Variant ServerSNX10
ExAC (Exome Aggregation Consortium)SNX10 (select the gene name)
Genetic variants : HAPMAP29887
Genomic Variants (DGV)SNX10 [DGVbeta]
DECIPHER (Syndromes)7:26331515-26413949  ENSG00000086300
CONAN: Copy Number AnalysisSNX10 
Mutations
ICGC Data PortalSNX10 
TCGA Data PortalSNX10 
Broad Tumor PortalSNX10
OASIS PortalSNX10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSNX10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSNX10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SNX10
DgiDB (Drug Gene Interaction Database)SNX10
DoCM (Curated mutations)SNX10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SNX10 (select a term)
intoGenSNX10
Cancer3DSNX10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614780    615085   
Orphanet2530   
MedgenSNX10
Genetic Testing Registry SNX10
NextProtQ9Y5X0 [Medical]
TSGene29887
GENETestsSNX10
Huge Navigator SNX10 [HugePedia]
snp3D : Map Gene to Disease29887
BioCentury BCIQSNX10
ClinGenSNX10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29887
Chemical/Pharm GKB GenePA37950
Clinical trialSNX10
Miscellaneous
canSAR (ICR)SNX10 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSNX10
EVEXSNX10
GoPubMedSNX10
iHOPSNX10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:20:21 CEST 2017

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