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SNX10 (sorting nexin 10)

Identity

Alias (NCBI)OPTB8
HGNC (Hugo) SNX10
LocusID (NCBI) 29887
Atlas_Id 54651
Location 7p15.2  [Link to chromosome band 7p15]
Location_base_pair Starts at 26291862 and ends at 26374382 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HDAC9 (7p21.1) / SNX10 (7p15.2)RASSF3 (12q14.2) / SNX10 (7p15.2)SKAP2 (7p15.2) / SNX10 (7p15.2)
SNX10 (7p15.2) / SEMA4A (1q22)HDAC9 7p21.1 / SNX10 7p15.2RASSF3 12q14.2 / SNX10 7p15.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SNX10   14974
Cards
Entrez_Gene (NCBI)SNX10    sorting nexin 10
AliasesOPTB8
GeneCards (Weizmann)SNX10
Ensembl hg19 (Hinxton)ENSG00000086300 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000086300 [Gene_View]  ENSG00000086300 [Sequence]  chr7:26291862-26374382 [Contig_View]  SNX10 [Vega]
ICGC DataPortalENSG00000086300
TCGA cBioPortalSNX10
AceView (NCBI)SNX10
Genatlas (Paris)SNX10
SOURCE (Princeton)SNX10
Genetics Home Reference (NIH)SNX10
Genomic and cartography
GoldenPath hg38 (UCSC)SNX10  -     chr7:26291862-26374382 +  7p15.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SNX10  -     7p15.2   [Description]    (hg19-Feb_2009)
GoldenPathSNX10 - 7p15.2 [CytoView hg19]  SNX10 - 7p15.2 [CytoView hg38]
ImmunoBaseENSG00000086300
Genome Data Viewer NCBISNX10 [Mapview hg19]  
OMIM614780   615085   
Gene and transcription
Genbank (Entrez)AF121860 AK296142 AK307905 AK309162 AK311256
RefSeq transcript (Entrez)NM_001199835 NM_001199837 NM_001199838 NM_001318198 NM_001318199 NM_001362753 NM_001362754 NM_013322
Consensus coding sequences : CCDS (NCBI)SNX10
Gene ExpressionSNX10 [ NCBI-GEO ]   SNX10 [ EBI - ARRAY_EXPRESS ]   SNX10 [ SEEK ]   SNX10 [ MEM ]
Gene Expression Viewer (FireBrowse)SNX10 [ Firebrowse - Broad ]
GenevisibleExpression of SNX10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29887
GTEX Portal (Tissue expression)SNX10
Human Protein AtlasENSG00000086300-SNX10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5X0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5X0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5X0
PhosPhoSitePlusQ9Y5X0
Domaine pattern : Prosite (Expaxy)PX (PS50195)   
Domains : Interpro (EBI)PX_dom    PX_dom_sf    SNX10/11   
Domain families : Pfam (Sanger)PX (PF00787)   
Domain families : Pfam (NCBI)pfam00787   
Domain families : Smart (EMBL)PX (SM00312)  
Conserved Domain (NCBI)SNX10
PDB (RSDB)4ON3    4PZG   
PDB Europe4ON3    4PZG   
PDB (PDBSum)4ON3    4PZG   
PDB (IMB)4ON3    4PZG   
Structural Biology KnowledgeBase4ON3    4PZG   
SCOP (Structural Classification of Proteins)4ON3    4PZG   
CATH (Classification of proteins structures)4ON3    4PZG   
SuperfamilyQ9Y5X0
AlphaFold pdb e-kbQ9Y5X0   
Human Protein Atlas [tissue]ENSG00000086300-SNX10 [tissue]
HPRD15409
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5X0
IntAct (EBI)Q9Y5X0
BioGRIDSNX10
STRING (EMBL)SNX10
ZODIACSNX10
Ontologies - Pathways
QuickGOQ9Y5X0
Ontology : AmiGOgastric acid secretion  protein binding  1-phosphatidylinositol binding  nucleus  endoplasmic reticulum  centrosome  intracellular protein transport  endocytosis  endosome organization  secretory granule  osteoclast differentiation  extrinsic component of endosome membrane  bone mineralization involved in bone maturation  tooth eruption  bone resorption  ATPase binding  calcium ion homeostasis  cilium assembly  protein localization to cilium  protein localization to centrosome  apical cytoplasm  ruffle assembly  cellular response to leukemia inhibitory factor  
Ontology : EGO-EBIgastric acid secretion  protein binding  1-phosphatidylinositol binding  nucleus  endoplasmic reticulum  centrosome  intracellular protein transport  endocytosis  endosome organization  secretory granule  osteoclast differentiation  extrinsic component of endosome membrane  bone mineralization involved in bone maturation  tooth eruption  bone resorption  ATPase binding  calcium ion homeostasis  cilium assembly  protein localization to cilium  protein localization to centrosome  apical cytoplasm  ruffle assembly  cellular response to leukemia inhibitory factor  
NDEx NetworkSNX10
Atlas of Cancer Signalling NetworkSNX10
Wikipedia pathwaysSNX10
Orthology - Evolution
OrthoDB29887
GeneTree (enSembl)ENSG00000086300
Phylogenetic Trees/Animal Genes : TreeFamSNX10
Homologs : HomoloGeneSNX10
Homology/Alignments : Family Browser (UCSC)SNX10
Gene fusions - Rearrangements
Fusion : MitelmanHDAC9/SNX10 [7p21.1/7p15.2]  
Fusion : MitelmanRASSF3/SNX10 [12q14.2/7p15.2]  
Fusion : MitelmanSKAP2/SNX10 [7p15.2/7p15.2]  
Fusion : QuiverSNX10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSNX10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SNX10
dbVarSNX10
ClinVarSNX10
MonarchSNX10
1000_GenomesSNX10 
Exome Variant ServerSNX10
GNOMAD BrowserENSG00000086300
Varsome BrowserSNX10
ACMGSNX10 variants
VarityQ9Y5X0
Genomic Variants (DGV)SNX10 [DGVbeta]
DECIPHERSNX10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSNX10 
Mutations
ICGC Data PortalSNX10 
TCGA Data PortalSNX10 
Broad Tumor PortalSNX10
OASIS PortalSNX10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSNX10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSNX10
Mutations and Diseases : HGMDSNX10
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSNX10
DgiDB (Drug Gene Interaction Database)SNX10
DoCM (Curated mutations)SNX10
CIViC (Clinical Interpretations of Variants in Cancer)SNX10
Cancer3DSNX10
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614780    615085   
Orphanet2530   
DisGeNETSNX10
MedgenSNX10
Genetic Testing Registry SNX10
NextProtQ9Y5X0 [Medical]
GENETestsSNX10
Target ValidationSNX10
Huge Navigator SNX10 [HugePedia]
ClinGenSNX10
Clinical trials, drugs, therapy
MyCancerGenomeSNX10
Protein Interactions : CTDSNX10
Pharm GKB GenePA37950
PharosQ9Y5X0
Clinical trialSNX10
Miscellaneous
canSAR (ICR)SNX10
HarmonizomeSNX10
DataMed IndexSNX10
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSNX10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:32:32 CEST 2021

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