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SNX18 (sorting nexin 18)

Identity

Alias_namesSNAG1
sorting nexin associated golgi protein 1
Alias_symbol (synonym)SH3PX2
SH3PXD3B
Other alias
HGNC (Hugo) SNX18
LocusID (NCBI) 112574
Atlas_Id 74052
Location 5q11.2  [Link to chromosome band 5q11]
Location_base_pair Starts at 53813593 and ends at 53842416 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HDAC4 (2q37.3) / SNX18 (5q11.2)SNX18 (5q11.2) / ANKRD55 (5q11.2)SNX18 (5q11.2) / SNX18 (5q11.2)
SNX18 (5q11.2) / WDR93 (15q26.1)SNX18 WDR93SNX18 ANKRD55

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SNX18   19245
Cards
Entrez_Gene (NCBI)SNX18  112574  sorting nexin 18
AliasesSH3PX2; SH3PXD3B; SNAG1
GeneCards (Weizmann)SNX18
Ensembl hg19 (Hinxton)ENSG00000178996 [Gene_View]  chr5:53813593-53842416 [Contig_View]  SNX18 [Vega]
Ensembl hg38 (Hinxton)ENSG00000178996 [Gene_View]  chr5:53813593-53842416 [Contig_View]  SNX18 [Vega]
ICGC DataPortalENSG00000178996
TCGA cBioPortalSNX18
AceView (NCBI)SNX18
Genatlas (Paris)SNX18
WikiGenes112574
SOURCE (Princeton)SNX18
Genetics Home Reference (NIH)SNX18
Genomic and cartography
GoldenPath hg19 (UCSC)SNX18  -     chr5:53813593-53842416 +  5q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SNX18  -     5q11.2   [Description]    (hg38-Dec_2013)
EnsemblSNX18 - 5q11.2 [CytoView hg19]  SNX18 - 5q11.2 [CytoView hg38]
Mapping of homologs : NCBISNX18 [Mapview hg19]  SNX18 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF395536 AI335241 AI669182 AK022059 AK057122
RefSeq transcript (Entrez)NM_001102575 NM_001145427 NM_052870
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_034772 NW_004929322
Consensus coding sequences : CCDS (NCBI)SNX18
Cluster EST : UnigeneHs.606166 [ NCBI ]
CGAP (NCI)Hs.606166
Alternative Splicing GalleryENSG00000178996
Gene ExpressionSNX18 [ NCBI-GEO ]   SNX18 [ EBI - ARRAY_EXPRESS ]   SNX18 [ SEEK ]   SNX18 [ MEM ]
Gene Expression Viewer (FireBrowse)SNX18 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)112574
GTEX Portal (Tissue expression)SNX18
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96RF0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96RF0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96RF0
Splice isoforms : SwissVarQ96RF0
PhosPhoSitePlusQ96RF0
Domaine pattern : Prosite (Expaxy)PX (PS50195)    SH3 (PS50002)   
Domains : Interpro (EBI)Phox    SH3_domain    SNX18    Snx9_subfam    Sorting_nexin_WASP-bd-dom   
Domain families : Pfam (Sanger)BAR_3_WASP_bdg (PF10456)    PX (PF00787)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam10456    pfam00787    pfam14604   
Domain families : Smart (EMBL)PX (SM00312)  SH3 (SM00326)  
Conserved Domain (NCBI)SNX18
DMDM Disease mutations112574
Blocks (Seattle)SNX18
SuperfamilyQ96RF0
Human Protein AtlasENSG00000178996
Peptide AtlasQ96RF0
HPRD15407
IPIIPI00045219   IPI00657938   IPI00923429   IPI00976895   
Protein Interaction databases
DIP (DOE-UCLA)Q96RF0
IntAct (EBI)Q96RF0
FunCoupENSG00000178996
BioGRIDSNX18
STRING (EMBL)SNX18
ZODIACSNX18
Ontologies - Pathways
QuickGOQ96RF0
Ontology : AmiGOmitotic cytokinesis  protein binding  phosphatidylinositol-4,5-bisphosphate binding  endosome  intracellular protein transport  endocytosis  endocytosis  mitotic nuclear division  endosome membrane  cytoplasmic membrane-bounded vesicle  vesicle organization  endosomal transport  clathrin-coated vesicle  growth cone  cytoplasmic vesicle membrane  extrinsic component of cytoplasmic side of plasma membrane  cleavage furrow formation  neuronal cell body  positive regulation of GTPase activity  extracellular exosome  
Ontology : EGO-EBImitotic cytokinesis  protein binding  phosphatidylinositol-4,5-bisphosphate binding  endosome  intracellular protein transport  endocytosis  endocytosis  mitotic nuclear division  endosome membrane  cytoplasmic membrane-bounded vesicle  vesicle organization  endosomal transport  clathrin-coated vesicle  growth cone  cytoplasmic vesicle membrane  extrinsic component of cytoplasmic side of plasma membrane  cleavage furrow formation  neuronal cell body  positive regulation of GTPase activity  extracellular exosome  
NDEx NetworkSNX18
Atlas of Cancer Signalling NetworkSNX18
Wikipedia pathwaysSNX18
Orthology - Evolution
OrthoDB112574
GeneTree (enSembl)ENSG00000178996
Phylogenetic Trees/Animal Genes : TreeFamSNX18
HOVERGENQ96RF0
HOGENOMQ96RF0
Homologs : HomoloGeneSNX18
Homology/Alignments : Family Browser (UCSC)SNX18
Gene fusions - Rearrangements
Fusion: TCGASNX18 WDR93
Fusion: TCGASNX18 ANKRD55
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSNX18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SNX18
dbVarSNX18
ClinVarSNX18
1000_GenomesSNX18 
Exome Variant ServerSNX18
ExAC (Exome Aggregation Consortium)SNX18 (select the gene name)
Genetic variants : HAPMAP112574
Genomic Variants (DGV)SNX18 [DGVbeta]
DECIPHER (Syndromes)5:53813593-53842416  ENSG00000178996
CONAN: Copy Number AnalysisSNX18 
Mutations
ICGC Data PortalSNX18 
TCGA Data PortalSNX18 
Broad Tumor PortalSNX18
OASIS PortalSNX18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSNX18  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSNX18
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SNX18
DgiDB (Drug Gene Interaction Database)SNX18
DoCM (Curated mutations)SNX18 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SNX18 (select a term)
intoGenSNX18
Cancer3DSNX18(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSNX18
Genetic Testing Registry SNX18
NextProtQ96RF0 [Medical]
TSGene112574
GENETestsSNX18
Huge Navigator SNX18 [HugePedia]
snp3D : Map Gene to Disease112574
BioCentury BCIQSNX18
ClinGenSNX18
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD112574
Chemical/Pharm GKB GenePA162404304
Clinical trialSNX18
Miscellaneous
canSAR (ICR)SNX18 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSNX18
EVEXSNX18
GoPubMedSNX18
iHOPSNX18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:46:05 CET 2017

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