SNX27 (sorting nexin 27)

2006-10-01  

Identity

HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
MRT1,MY014
FUSION GENES

Other Information

Locus ID:

NCBI: 81609
MIM: 611541
HGNC: 20073
Ensembl: ENSG00000143376

Variants:

dbSNP: 81609
ClinVar: 81609
TCGA: ENSG00000143376
COSMIC: SNX27

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143376ENST00000368841H7C603
ENSG00000143376ENST00000368843Q96L92
ENSG00000143376ENST00000458013Q96L92
ENSG00000143376ENST00000482791A0A2R8Y3S6
ENSG00000143376ENST00000642349A0A2R8YD75
ENSG00000143376ENST00000642376A0A2R8Y8A7
ENSG00000143376ENST00000642479A0A2R8Y871

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

References

Pubmed IDYearTitleCitations
216027912011SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors.194
235634912013A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport.168
207330532010SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane.112
178282612007A unique sorting nexin regulates trafficking of potassium channels via a PDZ domain interaction.70
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
251361262014A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.61
154668852004New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting.49
213007872011Deficiency of sorting nexin 27 (SNX27) leads to growth retardation and elevated levels of N-methyl-D-aspartate receptor 2C (NR2C).48
173511512007Proteomics identification of sorting nexin 27 as a diacylglycerol kinase zeta-associated protein: new diacylglycerol kinase roles in endocytic recycling.33
252785522014Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling.32

Citation

Dessen P

SNX27 (sorting nexin 27)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43499/snx27