Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SNX33 (sorting nexin 33)

Identity

Alias (NCBI)SH3PX3
SH3PXD3C
SNX30
HGNC (Hugo) SNX33
HGNC Alias symbMGC32065
SH3PXD3C
SNX30
HGNC Previous nameSH3PX3
HGNC Previous nameSH3 and PX domain containing 3
LocusID (NCBI) 257364
Atlas_Id 74062
Location 15q24.2  [Link to chromosome band 15q24]
Location_base_pair Starts at 75649007 and ends at 75658627 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FBXO22 (15q24.2) / SNX33 (15q24.2)HDLBP (2q37.3) / SNX33 (15q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  FBXO22/SNX33 (15q24)


External links

Nomenclature
HGNC (Hugo)SNX33   28468
Cards
Entrez_Gene (NCBI)SNX33  257364  sorting nexin 33
AliasesSH3PX3; SH3PXD3C; SNX30
GeneCards (Weizmann)SNX33
Ensembl hg19 (Hinxton)ENSG00000173548 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173548 [Gene_View]  ENSG00000173548 [Sequence]  chr15:75649007-75658627 [Contig_View]  SNX33 [Vega]
ICGC DataPortalENSG00000173548
TCGA cBioPortalSNX33
AceView (NCBI)SNX33
Genatlas (Paris)SNX33
WikiGenes257364
SOURCE (Princeton)SNX33
Genetics Home Reference (NIH)SNX33
Genomic and cartography
GoldenPath hg38 (UCSC)SNX33  -     chr15:75649007-75658627 +  15q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SNX33  -     15q24.2   [Description]    (hg19-Feb_2009)
GoldenPathSNX33 - 15q24.2 [CytoView hg19]  SNX33 - 15q24.2 [CytoView hg38]
ImmunoBaseENSG00000173548
genome Data Viewer NCBISNX33 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK091291 AK126563 AL833039 BC018775 EF219141
RefSeq transcript (Entrez)NM_001318146 NM_153271
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SNX33
Alternative Splicing GalleryENSG00000173548
Gene ExpressionSNX33 [ NCBI-GEO ]   SNX33 [ EBI - ARRAY_EXPRESS ]   SNX33 [ SEEK ]   SNX33 [ MEM ]
Gene Expression Viewer (FireBrowse)SNX33 [ Firebrowse - Broad ]
GenevisibleExpression of SNX33 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)257364
GTEX Portal (Tissue expression)SNX33
Human Protein AtlasENSG00000173548-SNX33 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WV41   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WV41  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WV41
Splice isoforms : SwissVarQ8WV41
PhosPhoSitePlusQ8WV41
Domaine pattern : Prosite (Expaxy)PX (PS50195)    SH3 (PS50002)   
Domains : Interpro (EBI)AH/BAR_dom_sf    Phox    PX_dom_sf    SH3-like_dom_sf    SH3_domain    SNX33    SNX33_BAR    Snx9_fam    Sorting_nexin_WASP-bd-dom   
Domain families : Pfam (Sanger)BAR_3_WASP_bdg (PF10456)    PX (PF00787)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam10456    pfam00787    pfam14604   
Domain families : Smart (EMBL)PX (SM00312)  SH3 (SM00326)  
Conserved Domain (NCBI)SNX33
DMDM Disease mutations257364
Blocks (Seattle)SNX33
PDB (RSDB)4AKV   
PDB Europe4AKV   
PDB (PDBSum)4AKV   
PDB (IMB)4AKV   
Structural Biology KnowledgeBase4AKV   
SCOP (Structural Classification of Proteins)4AKV   
CATH (Classification of proteins structures)4AKV   
SuperfamilyQ8WV41
Human Protein Atlas [tissue]ENSG00000173548-SNX33 [tissue]
Peptide AtlasQ8WV41
HPRD11331
IPIIPI00103013   
Protein Interaction databases
DIP (DOE-UCLA)Q8WV41
IntAct (EBI)Q8WV41
FunCoupENSG00000173548
BioGRIDSNX33
STRING (EMBL)SNX33
ZODIACSNX33
Ontologies - Pathways
QuickGOQ8WV41
Ontology : AmiGOmitotic cytokinesis  protein binding  cytosol  intracellular protein transport  endocytosis  endosome organization  membrane  endosomal transport  protein import  extrinsic component of membrane  cytoplasmic vesicle membrane  cytoplasmic vesicle  phosphatidylinositol binding  cleavage furrow formation  identical protein binding  macropinocytosis  negative regulation of endocytosis  positive regulation of membrane protein ectodomain proteolysis  plasma membrane tubulation  negative regulation of protein localization to cell surface  positive regulation of protein localization to cell surface  
Ontology : EGO-EBImitotic cytokinesis  protein binding  cytosol  intracellular protein transport  endocytosis  endosome organization  membrane  endosomal transport  protein import  extrinsic component of membrane  cytoplasmic vesicle membrane  cytoplasmic vesicle  phosphatidylinositol binding  cleavage furrow formation  identical protein binding  macropinocytosis  negative regulation of endocytosis  positive regulation of membrane protein ectodomain proteolysis  plasma membrane tubulation  negative regulation of protein localization to cell surface  positive regulation of protein localization to cell surface  
NDEx NetworkSNX33
Atlas of Cancer Signalling NetworkSNX33
Wikipedia pathwaysSNX33
Orthology - Evolution
OrthoDB257364
GeneTree (enSembl)ENSG00000173548
Phylogenetic Trees/Animal Genes : TreeFamSNX33
HOGENOMQ8WV41
Homologs : HomoloGeneSNX33
Homology/Alignments : Family Browser (UCSC)SNX33
Gene fusions - Rearrangements
Fusion : QuiverSNX33
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSNX33 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SNX33
dbVarSNX33
ClinVarSNX33
1000_GenomesSNX33 
Exome Variant ServerSNX33
GNOMAD BrowserENSG00000173548
Varsome BrowserSNX33
Genetic variants : HAPMAP257364
Genomic Variants (DGV)SNX33 [DGVbeta]
DECIPHERSNX33 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSNX33 
Mutations
ICGC Data PortalSNX33 
TCGA Data PortalSNX33 
Broad Tumor PortalSNX33
OASIS PortalSNX33 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSNX33  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSNX33
Mutations and Diseases : HGMDSNX33
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SNX33
DgiDB (Drug Gene Interaction Database)SNX33
DoCM (Curated mutations)SNX33 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SNX33 (select a term)
intoGenSNX33
Cancer3DSNX33(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETSNX33
MedgenSNX33
Genetic Testing Registry SNX33
NextProtQ8WV41 [Medical]
TSGene257364
GENETestsSNX33
Target ValidationSNX33
Huge Navigator SNX33 [HugePedia]
snp3D : Map Gene to Disease257364
BioCentury BCIQSNX33
ClinGenSNX33
Clinical trials, drugs, therapy
Protein Interactions : CTD257364
Pharm GKB GenePA162404345
Clinical trialSNX33
Miscellaneous
canSAR (ICR)SNX33 (select the gene name)
HarmonizomeSNX33
DataMed IndexSNX33
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSNX33
EVEXSNX33
GoPubMedSNX33
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 16:30:46 CEST 2020

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