SNX8 (sorting nexin 8)

2014-11-01  

Identity

HGNC
SNX8
LOCATION
7p22.3
LOCUSID
29886
ALIAS
Mvp1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 29886
MIM: 614905
HGNC: 14972
Ensembl: ENSG00000106266

Variants:

dbSNP: 29886
ClinVar: 29886
TCGA: ENSG00000106266
COSMIC: SNX8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106266ENST00000222990Q9Y5X2
ENSG00000106266ENST00000419693C9IYC5
ENSG00000106266ENST00000435060C9J271
ENSG00000106266ENST00000435336C9J8E6
ENSG00000106266ENST00000447136C9JCB9
ENSG00000106266ENST00000457286C9J014

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
219730562012SNX-BAR-mediated endosome tubulation is co-ordinated with endosome maturation.54
291804172017SNX8 mediates IFNγ-triggered noncanonical signaling pathway and host defense against Listeria monocytogenes.6
243115142014SNX8: A candidate gene for 7p22 cardiac malformations including tetralogy of fallot.2

Citation

Dessen P

SNX8 (sorting nexin 8)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74064/snx8