Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SNX9 (sorting nexin 9)

Identity

Alias_symbol (synonym)SH3PX1
SDP1
SH3PXD3A
Other aliasWISP
HGNC (Hugo) SNX9
LocusID (NCBI) 51429
Atlas_Id 54654
Location 6q25.3  [Link to chromosome band 6q25]
Location_base_pair Starts at 157823171 and ends at 157945077 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARID1B (6q25.3) / SNX9 (6q25.3)DAP (5p15.2) / SNX9 (6q25.3)SNX9 (6q25.3) / CYP2C19 (10q23.33)
SNX9 (6q25.3) / DAP (5p15.2)SNX9 (6q25.3) / PIP5K1C (19p13.3)SNX9 (6q25.3) / SNX9 (6q25.3)
ARID1B 6q25.3 / SNX9 6q25.3DAP 5p15.2 / SNX9 6q25.3SNX9 6q25.3 / DAP 5p15.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SNX9   14973
Cards
Entrez_Gene (NCBI)SNX9  51429  sorting nexin 9
AliasesSDP1; SH3PX1; SH3PXD3A; WISP
GeneCards (Weizmann)SNX9
Ensembl hg19 (Hinxton)ENSG00000130340 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130340 [Gene_View]  chr6:157823171-157945077 [Contig_View]  SNX9 [Vega]
ICGC DataPortalENSG00000130340
TCGA cBioPortalSNX9
AceView (NCBI)SNX9
Genatlas (Paris)SNX9
WikiGenes51429
SOURCE (Princeton)SNX9
Genetics Home Reference (NIH)SNX9
Genomic and cartography
GoldenPath hg38 (UCSC)SNX9  -     chr6:157823171-157945077 +  6q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SNX9  -     6q25.3   [Description]    (hg19-Feb_2009)
EnsemblSNX9 - 6q25.3 [CytoView hg19]  SNX9 - 6q25.3 [CytoView hg38]
Mapping of homologs : NCBISNX9 [Mapview hg19]  SNX9 [Mapview hg38]
OMIM605952   
Gene and transcription
Genbank (Entrez)AB209736 AF001629 AF076957 AF121859 AF131214
RefSeq transcript (Entrez)NM_016224
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SNX9
Cluster EST : UnigeneHs.191213 [ NCBI ]
CGAP (NCI)Hs.191213
Alternative Splicing GalleryENSG00000130340
Gene ExpressionSNX9 [ NCBI-GEO ]   SNX9 [ EBI - ARRAY_EXPRESS ]   SNX9 [ SEEK ]   SNX9 [ MEM ]
Gene Expression Viewer (FireBrowse)SNX9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51429
GTEX Portal (Tissue expression)SNX9
Human Protein AtlasENSG00000130340-SNX9 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5X1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5X1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5X1
Splice isoforms : SwissVarQ9Y5X1
PhosPhoSitePlusQ9Y5X1
Domaine pattern : Prosite (Expaxy)PX (PS50195)    SH3 (PS50002)   
Domains : Interpro (EBI)Phox    SH3_domain    SNX9    Snx9_subfam    Sorting_nexin_WASP-bd-dom   
Domain families : Pfam (Sanger)BAR_3_WASP_bdg (PF10456)    PX (PF00787)    SH3_1 (PF00018)   
Domain families : Pfam (NCBI)pfam10456    pfam00787    pfam00018   
Domain families : Smart (EMBL)PX (SM00312)  SH3 (SM00326)  
Conserved Domain (NCBI)SNX9
DMDM Disease mutations51429
Blocks (Seattle)SNX9
PDB (SRS)2RAI    2RAJ    2RAK    3DYT    3DYU    3LGE   
PDB (PDBSum)2RAI    2RAJ    2RAK    3DYT    3DYU    3LGE   
PDB (IMB)2RAI    2RAJ    2RAK    3DYT    3DYU    3LGE   
PDB (RSDB)2RAI    2RAJ    2RAK    3DYT    3DYU    3LGE   
Structural Biology KnowledgeBase2RAI    2RAJ    2RAK    3DYT    3DYU    3LGE   
SCOP (Structural Classification of Proteins)2RAI    2RAJ    2RAK    3DYT    3DYU    3LGE   
CATH (Classification of proteins structures)2RAI    2RAJ    2RAK    3DYT    3DYU    3LGE   
SuperfamilyQ9Y5X1
Human Protein Atlas [tissue]ENSG00000130340-SNX9 [tissue]
Peptide AtlasQ9Y5X1
HPRD12072
IPIIPI00001883   IPI01013758   IPI00744897   IPI00385075   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5X1
IntAct (EBI)Q9Y5X1
FunCoupENSG00000130340
BioGRIDSNX9
STRING (EMBL)SNX9
ZODIACSNX9
Ontologies - Pathways
QuickGOQ9Y5X1
Ontology : AmiGOmitotic cytokinesis  ruffle  protein binding  1-phosphatidylinositol binding  cytoplasm  trans-Golgi network  cytosol  cytosol  plasma membrane  intracellular protein transport  endocytosis  receptor-mediated endocytosis  endosomal transport  clathrin-coated vesicle  cytoplasmic vesicle membrane  extrinsic component of cytoplasmic side of plasma membrane  cytoplasmic vesicle  ubiquitin protein ligase binding  positive regulation of protein oligomerization  phosphatidylinositol binding  cleavage furrow formation  protein homodimerization activity  positive regulation of GTPase activity  cadherin binding  positive regulation of protein kinase activity  positive regulation of membrane protein ectodomain proteolysis  lipid tube assembly  membrane organization  extracellular exosome  Arp2/3 complex binding  plasma membrane tubulation  
Ontology : EGO-EBImitotic cytokinesis  ruffle  protein binding  1-phosphatidylinositol binding  cytoplasm  trans-Golgi network  cytosol  cytosol  plasma membrane  intracellular protein transport  endocytosis  receptor-mediated endocytosis  endosomal transport  clathrin-coated vesicle  cytoplasmic vesicle membrane  extrinsic component of cytoplasmic side of plasma membrane  cytoplasmic vesicle  ubiquitin protein ligase binding  positive regulation of protein oligomerization  phosphatidylinositol binding  cleavage furrow formation  protein homodimerization activity  positive regulation of GTPase activity  cadherin binding  positive regulation of protein kinase activity  positive regulation of membrane protein ectodomain proteolysis  lipid tube assembly  membrane organization  extracellular exosome  Arp2/3 complex binding  plasma membrane tubulation  
NDEx NetworkSNX9
Atlas of Cancer Signalling NetworkSNX9
Wikipedia pathwaysSNX9
Orthology - Evolution
OrthoDB51429
GeneTree (enSembl)ENSG00000130340
Phylogenetic Trees/Animal Genes : TreeFamSNX9
HOVERGENQ9Y5X1
HOGENOMQ9Y5X1
Homologs : HomoloGeneSNX9
Homology/Alignments : Family Browser (UCSC)SNX9
Gene fusions - Rearrangements
Fusion : MitelmanARID1B/SNX9 [6q25.3/6q25.3]  [t(6;6)(q25;q25)]  
Fusion : MitelmanDAP/SNX9 [5p15.2/6q25.3]  [t(5;6)(p15;q25)]  
Fusion : MitelmanSNX9/DAP [6q25.3/5p15.2]  [t(5;6)(p15;q25)]  
Fusion: TCGA_MDACCARID1B 6q25.3 SNX9 6q25.3 BRCA
Fusion: TCGA_MDACCDAP 5p15.2 SNX9 6q25.3 BRCA
Fusion: TCGA_MDACCSNX9 6q25.3 DAP 5p15.2 BRCA
Tumor Fusion PortalSNX9
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSNX9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SNX9
dbVarSNX9
ClinVarSNX9
1000_GenomesSNX9 
Exome Variant ServerSNX9
ExAC (Exome Aggregation Consortium)ENSG00000130340
GNOMAD BrowserENSG00000130340
Genetic variants : HAPMAP51429
Genomic Variants (DGV)SNX9 [DGVbeta]
DECIPHERSNX9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSNX9 
Mutations
ICGC Data PortalSNX9 
TCGA Data PortalSNX9 
Broad Tumor PortalSNX9
OASIS PortalSNX9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSNX9  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSNX9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SNX9
DgiDB (Drug Gene Interaction Database)SNX9
DoCM (Curated mutations)SNX9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SNX9 (select a term)
intoGenSNX9
Cancer3DSNX9(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605952   
Orphanet
DisGeNETSNX9
MedgenSNX9
Genetic Testing Registry SNX9
NextProtQ9Y5X1 [Medical]
TSGene51429
GENETestsSNX9
Target ValidationSNX9
Huge Navigator SNX9 [HugePedia]
snp3D : Map Gene to Disease51429
BioCentury BCIQSNX9
ClinGenSNX9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51429
Chemical/Pharm GKB GenePA37949
Clinical trialSNX9
Miscellaneous
canSAR (ICR)SNX9 (select the gene name)
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSNX9
EVEXSNX9
GoPubMedSNX9
iHOPSNX9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:35:56 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.