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SOAT2 (sterol O-acyltransferase 2)

Identity

Alias_symbol (synonym)ACAT2
Other aliasACACT2
ARGP2
HGNC (Hugo) SOAT2
LocusID (NCBI) 8435
Atlas_Id 47619
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 53103490 and ends at 53124539 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SOAT2   11178
Cards
Entrez_Gene (NCBI)SOAT2  8435  sterol O-acyltransferase 2
AliasesACACT2; ACAT2; ARGP2
GeneCards (Weizmann)SOAT2
Ensembl hg19 (Hinxton)ENSG00000167780 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167780 [Gene_View]  chr12:53103490-53124539 [Contig_View]  SOAT2 [Vega]
ICGC DataPortalENSG00000167780
TCGA cBioPortalSOAT2
AceView (NCBI)SOAT2
Genatlas (Paris)SOAT2
WikiGenes8435
SOURCE (Princeton)SOAT2
Genetics Home Reference (NIH)SOAT2
Genomic and cartography
GoldenPath hg38 (UCSC)SOAT2  -     chr12:53103490-53124539 +  12q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SOAT2  -     12q13.13   [Description]    (hg19-Feb_2009)
EnsemblSOAT2 - 12q13.13 [CytoView hg19]  SOAT2 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBISOAT2 [Mapview hg19]  SOAT2 [Mapview hg38]
OMIM601311   
Gene and transcription
Genbank (Entrez)AF059203 AF099031 BC096090 BC096091 BC096092
RefSeq transcript (Entrez)NM_003578
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SOAT2
Cluster EST : UnigeneHs.656544 [ NCBI ]
CGAP (NCI)Hs.656544
Alternative Splicing GalleryENSG00000167780
Gene ExpressionSOAT2 [ NCBI-GEO ]   SOAT2 [ EBI - ARRAY_EXPRESS ]   SOAT2 [ SEEK ]   SOAT2 [ MEM ]
Gene Expression Viewer (FireBrowse)SOAT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8435
GTEX Portal (Tissue expression)SOAT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75908   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75908  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75908
Splice isoforms : SwissVarO75908
Catalytic activity : Enzyme2.3.1.26 [ Enzyme-Expasy ]   2.3.1.262.3.1.26 [ IntEnz-EBI ]   2.3.1.26 [ BRENDA ]   2.3.1.26 [ KEGG ]   
PhosPhoSitePlusO75908
Domains : Interpro (EBI)MBOAT_fam    Oat_ACAT_DAG_ARE    Sterol_acyltranf_meta   
Domain families : Pfam (Sanger)MBOAT (PF03062)   
Domain families : Pfam (NCBI)pfam03062   
Conserved Domain (NCBI)SOAT2
DMDM Disease mutations8435
Blocks (Seattle)SOAT2
SuperfamilyO75908
Human Protein AtlasENSG00000167780
Peptide AtlasO75908
HPRD03202
IPIIPI00020669   IPI01015771   IPI01022149   
Protein Interaction databases
DIP (DOE-UCLA)O75908
IntAct (EBI)O75908
FunCoupENSG00000167780
BioGRIDSOAT2
STRING (EMBL)SOAT2
ZODIACSOAT2
Ontologies - Pathways
QuickGOO75908
Ontology : AmiGOfatty-acyl-CoA binding  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  brush border  receptor-mediated endocytosis  cholesterol metabolic process  macrophage derived foam cell differentiation  cholesterol binding  integral component of membrane  transferase activity, transferring acyl groups  intestinal cholesterol absorption  cholesterol efflux  very-low-density lipoprotein particle assembly  cholesterol esterification  cholesterol O-acyltransferase activity  cholesterol O-acyltransferase activity  cholesterol homeostasis  
Ontology : EGO-EBIfatty-acyl-CoA binding  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  brush border  receptor-mediated endocytosis  cholesterol metabolic process  macrophage derived foam cell differentiation  cholesterol binding  integral component of membrane  transferase activity, transferring acyl groups  intestinal cholesterol absorption  cholesterol efflux  very-low-density lipoprotein particle assembly  cholesterol esterification  cholesterol O-acyltransferase activity  cholesterol O-acyltransferase activity  cholesterol homeostasis  
Pathways : KEGGSteroid biosynthesis   
NDEx NetworkSOAT2
Atlas of Cancer Signalling NetworkSOAT2
Wikipedia pathwaysSOAT2
Orthology - Evolution
OrthoDB8435
GeneTree (enSembl)ENSG00000167780
Phylogenetic Trees/Animal Genes : TreeFamSOAT2
HOVERGENO75908
HOGENOMO75908
Homologs : HomoloGeneSOAT2
Homology/Alignments : Family Browser (UCSC)SOAT2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSOAT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SOAT2
dbVarSOAT2
ClinVarSOAT2
1000_GenomesSOAT2 
Exome Variant ServerSOAT2
ExAC (Exome Aggregation Consortium)SOAT2 (select the gene name)
Genetic variants : HAPMAP8435
Genomic Variants (DGV)SOAT2 [DGVbeta]
DECIPHERSOAT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSOAT2 
Mutations
ICGC Data PortalSOAT2 
TCGA Data PortalSOAT2 
Broad Tumor PortalSOAT2
OASIS PortalSOAT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSOAT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSOAT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SOAT2
DgiDB (Drug Gene Interaction Database)SOAT2
DoCM (Curated mutations)SOAT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SOAT2 (select a term)
intoGenSOAT2
Cancer3DSOAT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601311   
Orphanet
MedgenSOAT2
Genetic Testing Registry SOAT2
NextProtO75908 [Medical]
TSGene8435
GENETestsSOAT2
Huge Navigator SOAT2 [HugePedia]
snp3D : Map Gene to Disease8435
BioCentury BCIQSOAT2
ClinGenSOAT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8435
Chemical/Pharm GKB GenePA36016
Clinical trialSOAT2
Miscellaneous
canSAR (ICR)SOAT2 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSOAT2
EVEXSOAT2
GoPubMedSOAT2
iHOPSOAT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:38:30 CEST 2017

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