SOD3 (superoxide dismutase 3)

2007-10-01  

Identity

HGNC
LOCATION
4p15.2
LOCUSID
ALIAS
EC-SOD

Other Information

Locus ID:

NCBI: 6649
MIM: 185490
HGNC: 11181
Ensembl: ENSG00000109610

Variants:

dbSNP: 6649
ClinVar: 6649
TCGA: ENSG00000109610
COSMIC: SOD3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109610ENST00000382120P08294
ENSG00000109610ENST00000382120A0A140VJU8
ENSG00000109610ENST00000598411M0R1V4

Expression (GTEx)

0
500
1000
1500

Pathways

PathwaySourceExternal ID
Cellular responses to stressREACTOMER-HSA-2262752
Detoxification of Reactive Oxygen SpeciesREACTOMER-HSA-3299685

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
151660092004Vascular protection: superoxide dismutase isoforms in the vessel wall.132
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
181652262008Extracellular superoxide dismutase inhibits inflammation by preventing oxidative fragmentation of hyaluronan.72
228367562012MicroRNA-21 modulates the levels of reactive oxygen species by targeting SOD3 and TNFα.65
185995022008Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling.64
166118092006Aging-dependent alterations in synaptic plasticity and memory in mice that overexpress extracellular superoxide dismutase.58
124759882003Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening.53
176462722007Functional variant of manganese superoxide dismutase (SOD2 V16A) polymorphism is associated with prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer study.53
176462722007Functional variant of manganese superoxide dismutase (SOD2 V16A) polymorphism is associated with prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer study.53
164670732006Functional variants of antioxidant genes in smokers with COPD and in those with normal lung function.48

Citation

Dessen P

SOD3 (superoxide dismutase 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-10-01

Online version: http://atlasgeneticsoncology.org/gene/49773/sod3