Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SOHLH2 (spermatogenesis and oogenesis specific basic helix-loop-helix 2)

Identity

Alias_symbol (synonym)FLJ20449
TEB1
bHLHe81
SPATA28
Other alias
HGNC (Hugo) SOHLH2
LocusID (NCBI) 54937
Atlas_Id 55087
Location 13q13.3  [Link to chromosome band 13q13]
Location_base_pair Starts at 36756129 and ends at 36788752 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PPP6R1 (19q13.42) / SOHLH2 (13q13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SOHLH2   26026
Cards
Entrez_Gene (NCBI)SOHLH2  54937  spermatogenesis and oogenesis specific basic helix-loop-helix 2
AliasesSPATA28; TEB1; bHLHe81
GeneCards (Weizmann)SOHLH2
Ensembl hg19 (Hinxton)ENSG00000120669 [Gene_View]  chr13:36756129-36788752 [Contig_View]  SOHLH2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000120669 [Gene_View]  chr13:36756129-36788752 [Contig_View]  SOHLH2 [Vega]
ICGC DataPortalENSG00000120669
TCGA cBioPortalSOHLH2
AceView (NCBI)SOHLH2
Genatlas (Paris)SOHLH2
WikiGenes54937
SOURCE (Princeton)SOHLH2
Genetics Home Reference (NIH)SOHLH2
Genomic and cartography
GoldenPath hg19 (UCSC)SOHLH2  -     chr13:36756129-36788752 -  13q13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SOHLH2  -     13q13.3   [Description]    (hg38-Dec_2013)
EnsemblSOHLH2 - 13q13.3 [CytoView hg19]  SOHLH2 - 13q13.3 [CytoView hg38]
Mapping of homologs : NCBISOHLH2 [Mapview hg19]  SOHLH2 [Mapview hg38]
OMIM616066   
Gene and transcription
Genbank (Entrez)AI368806 AK000456 AY884305 BC025383 DB022954
RefSeq transcript (Entrez)NM_001282147 NM_017826
RefSeq genomic (Entrez)NC_000013 NC_018924 NG_033786 NT_024524 NW_004929388
Consensus coding sequences : CCDS (NCBI)SOHLH2
Cluster EST : UnigeneHs.124519 [ NCBI ]
CGAP (NCI)Hs.124519
Alternative Splicing GalleryENSG00000120669
Gene ExpressionSOHLH2 [ NCBI-GEO ]   SOHLH2 [ EBI - ARRAY_EXPRESS ]   SOHLH2 [ SEEK ]   SOHLH2 [ MEM ]
Gene Expression Viewer (FireBrowse)SOHLH2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54937
GTEX Portal (Tissue expression)SOHLH2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NX45   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NX45  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NX45
Splice isoforms : SwissVarQ9NX45
PhosPhoSitePlusQ9NX45
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom    SOHLH2   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)SOHLH2
DMDM Disease mutations54937
Blocks (Seattle)SOHLH2
SuperfamilyQ9NX45
Human Protein AtlasENSG00000120669
Peptide AtlasQ9NX45
HPRD07910
IPIIPI00942235   IPI00844551   IPI00963860   
Protein Interaction databases
DIP (DOE-UCLA)Q9NX45
IntAct (EBI)Q9NX45
FunCoupENSG00000120669
BioGRIDSOHLH2
STRING (EMBL)SOHLH2
ZODIACSOHLH2
Ontologies - Pathways
QuickGOQ9NX45
Ontology : AmiGOcore promoter sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  nucleus  transcription from RNA polymerase II promoter  multicellular organism development  spermatogenesis  cell differentiation  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  oogenesis  
Ontology : EGO-EBIcore promoter sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  nucleus  transcription from RNA polymerase II promoter  multicellular organism development  spermatogenesis  cell differentiation  positive regulation of transcription from RNA polymerase II promoter  protein dimerization activity  oogenesis  
NDEx NetworkSOHLH2
Atlas of Cancer Signalling NetworkSOHLH2
Wikipedia pathwaysSOHLH2
Orthology - Evolution
OrthoDB54937
GeneTree (enSembl)ENSG00000120669
Phylogenetic Trees/Animal Genes : TreeFamSOHLH2
HOVERGENQ9NX45
HOGENOMQ9NX45
Homologs : HomoloGeneSOHLH2
Homology/Alignments : Family Browser (UCSC)SOHLH2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSOHLH2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SOHLH2
dbVarSOHLH2
ClinVarSOHLH2
1000_GenomesSOHLH2 
Exome Variant ServerSOHLH2
ExAC (Exome Aggregation Consortium)SOHLH2 (select the gene name)
Genetic variants : HAPMAP54937
Genomic Variants (DGV)SOHLH2 [DGVbeta]
DECIPHER (Syndromes)13:36756129-36788752  ENSG00000120669
CONAN: Copy Number AnalysisSOHLH2 
Mutations
ICGC Data PortalSOHLH2 
TCGA Data PortalSOHLH2 
Broad Tumor PortalSOHLH2
OASIS PortalSOHLH2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSOHLH2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSOHLH2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SOHLH2
DgiDB (Drug Gene Interaction Database)SOHLH2
DoCM (Curated mutations)SOHLH2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SOHLH2 (select a term)
intoGenSOHLH2
Cancer3DSOHLH2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616066   
Orphanet
MedgenSOHLH2
Genetic Testing Registry SOHLH2
NextProtQ9NX45 [Medical]
TSGene54937
GENETestsSOHLH2
Huge Navigator SOHLH2 [HugePedia]
snp3D : Map Gene to Disease54937
BioCentury BCIQSOHLH2
ClinGenSOHLH2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54937
Chemical/Pharm GKB GenePA144596273
Clinical trialSOHLH2
Miscellaneous
canSAR (ICR)SOHLH2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSOHLH2
EVEXSOHLH2
GoPubMedSOHLH2
iHOPSOHLH2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:20:24 CEST 2017

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