Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SON (SON DNA binding protein)

Identity

Alias_namesC21orf50
Alias_symbol (synonym)DBP-5
NREBP
KIAA1019
BASS1
FLJ21099
FLJ33914
Other aliasSON3
TOKIMS
HGNC (Hugo) SON
LocusID (NCBI) 6651
Atlas_Id 42354
Location 21q22.11  [Link to chromosome band 21q22]
Location_base_pair Starts at 33543038 and ends at 33559056 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CD27 (12p13.31) / SON (21q22.11)CSPG4 (15q24.2) / SON (21q22.11)EPB41L2 (6q23.1) / SON (21q22.11)
GAPDH (12p13.31) / SON (21q22.11)KAT8 (16p11.2) / SON (21q22.11)PPFIA2 (12q21.31) / SON (21q22.11)
SON (21q22.11) / C10orf11 (10q22.2)SON (21q22.11) / CD44 (11p13)SON (21q22.11) / KLF6 (10p15.1)
SON (21q22.11) / RPL12 (9q33.3)SON (21q22.11) / XPC (3p25.1)SON 21q22.11 / C10orf11 10q22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SON   11183
Cards
Entrez_Gene (NCBI)SON  6651  SON DNA binding protein
AliasesBASS1; C21orf50; DBP-5; NREBP; 
SON3; TOKIMS
GeneCards (Weizmann)SON
Ensembl hg19 (Hinxton)ENSG00000159140 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159140 [Gene_View]  chr21:33543038-33559056 [Contig_View]  SON [Vega]
ICGC DataPortalENSG00000159140
TCGA cBioPortalSON
AceView (NCBI)SON
Genatlas (Paris)SON
WikiGenes6651
SOURCE (Princeton)SON
Genetics Home Reference (NIH)SON
Genomic and cartography
GoldenPath hg38 (UCSC)SON  -     chr21:33543038-33559056 +  21q22.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SON  -     21q22.11   [Description]    (hg19-Feb_2009)
EnsemblSON - 21q22.11 [CytoView hg19]  SON - 21q22.11 [CytoView hg38]
Mapping of homologs : NCBISON [Mapview hg19]  SON [Mapview hg38]
OMIM182465   617140   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001291411 NM_001291412 NM_003103 NM_032195 NM_138925 NM_138927
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SON
Cluster EST : UnigeneHs.656725 [ NCBI ]
CGAP (NCI)Hs.656725
Alternative Splicing GalleryENSG00000159140
Gene ExpressionSON [ NCBI-GEO ]   SON [ EBI - ARRAY_EXPRESS ]   SON [ SEEK ]   SON [ MEM ]
Gene Expression Viewer (FireBrowse)SON [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6651
GTEX Portal (Tissue expression)SON
Protein : pattern, domain, 3D structure
UniProt/SwissProtP18583   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP18583  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP18583
Splice isoforms : SwissVarP18583
PhosPhoSitePlusP18583
Domaine pattern : Prosite (Expaxy)DS_RBD (PS50137)    G_PATCH (PS50174)   
Domains : Interpro (EBI)dsRBD_dom    G_patch_dom    SON    WD40/YVTN_repeat-like_dom    WD40_repeat_dom   
Domain families : Pfam (Sanger)G-patch (PF01585)   
Domain families : Pfam (NCBI)pfam01585   
Domain families : Smart (EMBL)G_patch (SM00443)  
Conserved Domain (NCBI)SON
DMDM Disease mutations6651
Blocks (Seattle)SON
SuperfamilyP18583
Human Protein AtlasENSG00000159140
Peptide AtlasP18583
HPRD01678
IPIIPI00000192   IPI00217930   IPI00748258   IPI00218618   IPI00218619   IPI00218620   IPI00218621   IPI00218622   IPI00218617   IPI00218624   IPI00903283   IPI00977070   IPI00444149   IPI00877777   IPI00968065   
Protein Interaction databases
DIP (DOE-UCLA)P18583
IntAct (EBI)P18583
FunCoupENSG00000159140
BioGRIDSON
STRING (EMBL)SON
ZODIACSON
Ontologies - Pathways
QuickGOP18583
Ontology : AmiGOmicrotubule cytoskeleton organization  mitotic cytokinesis  DNA binding  RNA binding  protein binding  mRNA processing  RNA splicing  nuclear speck  negative regulation of apoptotic process  regulation of RNA splicing  regulation of mRNA splicing, via spliceosome  RS domain binding  regulation of cell cycle  
Ontology : EGO-EBImicrotubule cytoskeleton organization  mitotic cytokinesis  DNA binding  RNA binding  protein binding  mRNA processing  RNA splicing  nuclear speck  negative regulation of apoptotic process  regulation of RNA splicing  regulation of mRNA splicing, via spliceosome  RS domain binding  regulation of cell cycle  
NDEx NetworkSON
Atlas of Cancer Signalling NetworkSON
Wikipedia pathwaysSON
Orthology - Evolution
OrthoDB6651
GeneTree (enSembl)ENSG00000159140
Phylogenetic Trees/Animal Genes : TreeFamSON
HOVERGENP18583
HOGENOMP18583
Homologs : HomoloGeneSON
Homology/Alignments : Family Browser (UCSC)SON
Gene fusions - Rearrangements
Fusion : MitelmanSON/C10orf11 [21q22.11/10q22.2]  
Fusion: TCGASON 21q22.11 C10orf11 10q22.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSON [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SON
dbVarSON
ClinVarSON
1000_GenomesSON 
Exome Variant ServerSON
ExAC (Exome Aggregation Consortium)SON (select the gene name)
Genetic variants : HAPMAP6651
Genomic Variants (DGV)SON [DGVbeta]
DECIPHERSON [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSON 
Mutations
ICGC Data PortalSON 
TCGA Data PortalSON 
Broad Tumor PortalSON
OASIS PortalSON [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSON  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSON
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SON
DgiDB (Drug Gene Interaction Database)SON
DoCM (Curated mutations)SON (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SON (select a term)
intoGenSON
Cancer3DSON(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182465    617140   
Orphanet
MedgenSON
Genetic Testing Registry SON
NextProtP18583 [Medical]
TSGene6651
GENETestsSON
Target ValidationSON
Huge Navigator SON [HugePedia]
snp3D : Map Gene to Disease6651
BioCentury BCIQSON
ClinGenSON
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6651
Chemical/Pharm GKB GenePA36020
Clinical trialSON
Miscellaneous
canSAR (ICR)SON (select the gene name)
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSON
EVEXSON
GoPubMedSON
iHOPSON
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:56:52 CEST 2017

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