Identity
HGNC
LOCATION
7p21.2
LOCUSID
ALIAS
CDA019,DAND7,ECTODIN,USAG1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25928
MIM: 609675
HGNC: 21748
Ensembl: ENSG00000171243
Variants:
dbSNP: 25928
ClinVar: 25928
TCGA: ENSG00000171243
COSMIC: SOSTDC1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171243 | ENST00000307068 | Q6X4U4 |
| ENSG00000171243 | ENST00000307068 | A4D125 |
| ENSG00000171243 | ENST00000396652 | Q6X4U4 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35138469 | 2022 | Exosomal circ_0001190 Regulates the Progression of Gastric Cancer via miR-586/SOSTDC1 Axis. | 5 |
| 35442555 | 2022 | SOSTDC1 acts as a tumor inhibitor in acute myeloid leukemia by downregulating the Wnt/β-catenin pathway. | 2 |
| 35138469 | 2022 | Exosomal circ_0001190 Regulates the Progression of Gastric Cancer via miR-586/SOSTDC1 Axis. | 5 |
| 35442555 | 2022 | SOSTDC1 acts as a tumor inhibitor in acute myeloid leukemia by downregulating the Wnt/β-catenin pathway. | 2 |
| 34911834 | 2021 | Impact of microRNA-21-5p on the growth of thyroid cancer cells via targeting the recombinant sclerostin domain containing protein 1. | 1 |
| 34911834 | 2021 | Impact of microRNA-21-5p on the growth of thyroid cancer cells via targeting the recombinant sclerostin domain containing protein 1. | 1 |
| 32779697 | 2020 | Characterization of the different oligomeric states of the DAN family antagonists SOSTDC1 and SOST. | 7 |
| 32779697 | 2020 | Characterization of the different oligomeric states of the DAN family antagonists SOSTDC1 and SOST. | 7 |
| 30367460 | 2019 | Differential expression of secreted factors SOSTDC1 and ADAMTS8 cause profibrotic changes in linear morphoea fibroblasts. | 9 |
| 31133012 | 2019 | Lack of association between PAX6/SOSTDC1/FAM20B gene polymorphisms and mesiodens. | 0 |
| 31391487 | 2019 | Downregulation of Sostdc1 in Testicular Sertoli Cells is Prerequisite for Onset of Robust Spermatogenesis at Puberty. | 5 |
| 31529323 | 2019 | Sostdc1 is expressed in all major compartments of developing and adult mammalian eyes. | 2 |
| 30367460 | 2019 | Differential expression of secreted factors SOSTDC1 and ADAMTS8 cause profibrotic changes in linear morphoea fibroblasts. | 9 |
| 31133012 | 2019 | Lack of association between PAX6/SOSTDC1/FAM20B gene polymorphisms and mesiodens. | 0 |
| 31391487 | 2019 | Downregulation of Sostdc1 in Testicular Sertoli Cells is Prerequisite for Onset of Robust Spermatogenesis at Puberty. | 5 |
Citation
Dessen P
SOSTDC1 (sclerostin domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-12-01
Online version: http://atlasgeneticsoncology.org/gene/50503/sostdc1
