SOX15 (SRY-box transcription factor 15)

2014-03-01  

Identity

HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
SOX20,SOX26,SOX27

Other Information

Locus ID:

NCBI: 6665
MIM: 601297
HGNC: 11196
Ensembl: ENSG00000129194

Variants:

dbSNP: 6665
ClinVar: 6665
TCGA: ENSG00000129194
COSMIC: SOX15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129194ENST00000250055O60248
ENSG00000129194ENST00000538513O60248
ENSG00000129194ENST00000570788O60248

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
233184272014SOX15 is a candidate tumor suppressor in pancreatic cancer with a potential role in Wnt/β-catenin signaling.23
181828462007Overexpression of SOX15 inhibits proliferation of NT2/D1 cells derived from a testicular embryonal cell carcinoma.5
185797252008Identification of NR5A1 (SF-1/AD4BP) gene expression modulators by large-scale gain and loss of function studies.4
278811252016Enhanced expression of the stemness-related factors OCT4, SOX15 and TWIST1 in ectopic endometrium of endometriosis patients.4
288215642017<i>SOX15</i> regulates proliferation and migration of endometrial cancer cells.1
300199152018Effects of SOX15 on the colorectal cancer cells via downregulation of the Wnt/β-catenin signaling pathway.0
324161682020SOX15 exerts antitumor function in glioma by inhibiting cell proliferation and invasion via downregulation of Wnt/β-catenin signaling.0

Citation

Dessen P

SOX15 (SRY-box transcription factor 15)

Atlas Genet Cytogenet Oncol Haematol. 2014-03-01

Online version: http://atlasgeneticsoncology.org/gene/53841/sox15