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SOX21 (SRY-box 21)

Identity

Alias_namesSRY (sex determining region Y)-box 21
SRY box 21
Alias_symbol (synonym)SOX25
Other alias
HGNC (Hugo) SOX21
LocusID (NCBI) 11166
Atlas_Id 53568
Location 13q32.1  [Link to chromosome band 13q32]
Location_base_pair Starts at 94709625 and ends at 94712543 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SOX21   11197
Cards
Entrez_Gene (NCBI)SOX21  11166  SRY-box 21
AliasesSOX25
GeneCards (Weizmann)SOX21
Ensembl hg19 (Hinxton)ENSG00000125285 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125285 [Gene_View]  chr13:94709625-94712543 [Contig_View]  SOX21 [Vega]
ICGC DataPortalENSG00000125285
TCGA cBioPortalSOX21
AceView (NCBI)SOX21
Genatlas (Paris)SOX21
WikiGenes11166
SOURCE (Princeton)SOX21
Genetics Home Reference (NIH)SOX21
Genomic and cartography
GoldenPath hg38 (UCSC)SOX21  -     chr13:94709625-94712543 -  13q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SOX21  -     13q32.1   [Description]    (hg19-Feb_2009)
EnsemblSOX21 - 13q32.1 [CytoView hg19]  SOX21 - 13q32.1 [CytoView hg38]
Mapping of homologs : NCBISOX21 [Mapview hg19]  SOX21 [Mapview hg38]
OMIM604974   
Gene and transcription
Genbank (Entrez)AI418194 AI569726 AI816765 BC111584 BM783159
RefSeq transcript (Entrez)NM_007084
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SOX21
Cluster EST : UnigeneHs.187577 [ NCBI ]
CGAP (NCI)Hs.187577
Alternative Splicing GalleryENSG00000125285
Gene ExpressionSOX21 [ NCBI-GEO ]   SOX21 [ EBI - ARRAY_EXPRESS ]   SOX21 [ SEEK ]   SOX21 [ MEM ]
Gene Expression Viewer (FireBrowse)SOX21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11166
GTEX Portal (Tissue expression)SOX21
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y651   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y651  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y651
Splice isoforms : SwissVarQ9Y651
PhosPhoSitePlusQ9Y651
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (EBI)HMG_box_dom    SOX_fam   
Domain families : Pfam (Sanger)HMG_box (PF00505)    SOXp (PF12336)   
Domain families : Pfam (NCBI)pfam00505    pfam12336   
Domain families : Smart (EMBL)HMG (SM00398)  
Conserved Domain (NCBI)SOX21
DMDM Disease mutations11166
Blocks (Seattle)SOX21
SuperfamilyQ9Y651
Human Protein AtlasENSG00000125285
Peptide AtlasQ9Y651
HPRD16083
IPIIPI00001824   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y651
IntAct (EBI)Q9Y651
FunCoupENSG00000125285
BioGRIDSOX21
STRING (EMBL)SOX21
ZODIACSOX21
Ontologies - Pathways
QuickGOQ9Y651
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  hair follicle development  DNA binding  transcription factor activity, sequence-specific DNA binding  cellular_component  nucleus  regulation of transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  stem cell differentiation  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  hair follicle development  DNA binding  transcription factor activity, sequence-specific DNA binding  cellular_component  nucleus  regulation of transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  stem cell differentiation  
NDEx NetworkSOX21
Atlas of Cancer Signalling NetworkSOX21
Wikipedia pathwaysSOX21
Orthology - Evolution
OrthoDB11166
GeneTree (enSembl)ENSG00000125285
Phylogenetic Trees/Animal Genes : TreeFamSOX21
HOVERGENQ9Y651
HOGENOMQ9Y651
Homologs : HomoloGeneSOX21
Homology/Alignments : Family Browser (UCSC)SOX21
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSOX21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SOX21
dbVarSOX21
ClinVarSOX21
1000_GenomesSOX21 
Exome Variant ServerSOX21
ExAC (Exome Aggregation Consortium)SOX21 (select the gene name)
Genetic variants : HAPMAP11166
Genomic Variants (DGV)SOX21 [DGVbeta]
DECIPHERSOX21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSOX21 
Mutations
ICGC Data PortalSOX21 
TCGA Data PortalSOX21 
Broad Tumor PortalSOX21
OASIS PortalSOX21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSOX21  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSOX21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SOX21
DgiDB (Drug Gene Interaction Database)SOX21
DoCM (Curated mutations)SOX21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SOX21 (select a term)
intoGenSOX21
Cancer3DSOX21(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604974   
Orphanet
MedgenSOX21
Genetic Testing Registry SOX21
NextProtQ9Y651 [Medical]
TSGene11166
GENETestsSOX21
Target ValidationSOX21
Huge Navigator SOX21 [HugePedia]
snp3D : Map Gene to Disease11166
BioCentury BCIQSOX21
ClinGenSOX21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11166
Chemical/Pharm GKB GenePA36034
Clinical trialSOX21
Miscellaneous
canSAR (ICR)SOX21 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSOX21
EVEXSOX21
GoPubMedSOX21
iHOPSOX21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:56:56 CEST 2017

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