| AC011443.1 () / SOX5 (12p12.1) | BICD1 (12p11.21) / SOX5 (12p12.1) | CP (3q24) / SOX5 (12p12.1) |
|
KIAA1535 () / SOX5 (12p12.1) | KIAA1551 (12p11.21) / SOX5 (12p12.1) | LRMP (12p12.1) / SOX5 (12p12.1) |
|
SOX5 (12p12.1) / AC007621.1 () | SOX5 (12p12.1) / MANSC1 (12p13.2) | SOX5 (12p12.1) / RP11-176H8.1 () |
|
SOX5 (12p12.1) / SOX5 (12p12.1) | SOX5 (12p12.1) / TGFBR2 (3p24.1) | TSPAN6 (Xq22.1) / SOX5 (12p12.1) |
|
AC011443.1 SOX5 12p12.1 | BICD1 12p11.21 / SOX5 12p12.1 | C12orf35 SOX5 12p12.1 |
|
CP 3q24 / SOX5 12p12.1 | SOX5 12p12.1 AC007621.1 | SOX5 12p12.1 / MANSC1 12p13.2 |
|
SOX5 12p12.1 RP11-176H8.1 |
| Nomenclature |
HGNC (Hugo) | SOX5 11201 |
| Cards |
Entrez_Gene (NCBI) | SOX5 SRY-box transcription factor 5 |
Aliases | L-SOX5; L-SOX5B; L-SOX5F; LAMSHF |
GeneCards (Weizmann) | SOX5 |
Ensembl hg19 (Hinxton) | ENSG00000134532 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000134532 [Gene_View]  ENSG00000134532 [Sequence] chr12:23529504-23584586 [Contig_View] SOX5 [Vega] |
ICGC DataPortal | ENSG00000134532 |
TCGA cBioPortal | SOX5 |
AceView (NCBI) | SOX5 |
Genatlas (Paris) | SOX5 |
SOURCE (Princeton) | SOX5 |
Genetics Home Reference (NIH) | SOX5 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | SOX5 - chr12:23529504-23584586 - 12p12.1 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | SOX5 - 12p12.1 [Description] (hg19-Feb_2009) |
GoldenPath | SOX5 - 12p12.1 [CytoView hg19] SOX5 - 12p12.1 [CytoView hg38] |
ImmunoBase | ENSG00000134532 |
genome Data Viewer NCBI | SOX5 [Mapview hg19] |
OMIM | 604975 616803 |
| Gene and transcription |
Genbank (Entrez) | AB081588 AB081589 AK074317 AK096569 AK098610 |
RefSeq transcript (Entrez) | NM_001261414 NM_001261415 NM_001330785 NM_006940 NM_152989 NM_178010 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | SOX5 |
Alternative Splicing Gallery | ENSG00000134532 |
Gene Expression | SOX5 [ NCBI-GEO ] SOX5 [ EBI - ARRAY_EXPRESS ]
SOX5 [ SEEK ] SOX5 [ MEM ] |
Gene Expression Viewer (FireBrowse) | SOX5 [ Firebrowse - Broad ] |
Genevisible | Expression of SOX5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 6660 |
GTEX Portal (Tissue expression) | SOX5 |
Human Protein Atlas | ENSG00000134532-SOX5 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | P35711 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | P35711 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | P35711 |
Splice isoforms : SwissVar | P35711 |
PhosPhoSitePlus | P35711 |
Domaine pattern : Prosite (Expaxy) | HMG_BOX_2 (PS50118) |
Domains : Interpro (EBI) | HMG_box_dom HMG_box_dom_sf SOX-5/6 |
Domain families : Pfam (Sanger) | HMG_box (PF00505) |
Domain families : Pfam (NCBI) | pfam00505 |
Domain families : Smart (EMBL) | HMG (SM00398) |
Conserved Domain (NCBI) | SOX5 |
Blocks (Seattle) | SOX5 |
Superfamily | P35711 |
Human Protein Atlas [tissue] | ENSG00000134532-SOX5 [tissue] |
Peptide Atlas | P35711 |
HPRD | 18086 |
IPI | IPI00216317 IPI00171247 IPI00221270 IPI00166143 IPI00793790 IPI01011755 IPI01010805 IPI00939555 IPI00791993 IPI01009605 IPI01015475 |
| Protein Interaction databases |
DIP (DOE-UCLA) | P35711 |
IntAct (EBI) | P35711 |
BioGRID | SOX5 |
STRING (EMBL) | SOX5 |
ZODIAC | SOX5 |
| Ontologies - Pathways |
QuickGO | P35711 |
Ontology : AmiGO | nuclear chromatin transcription regulatory region sequence-specific DNA binding transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cartilage condensation chondrocyte differentiation DNA-binding transcription factor activity protein binding nucleus transcription by RNA polymerase II positive regulation of chondrocyte differentiation positive regulation of chondrocyte differentiation cell fate commitment negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II cartilage development asymmetric neuroblast division positive regulation of cartilage development cellular response to transforming growth factor beta stimulus positive regulation of mesenchymal stem cell differentiation |
Ontology : EGO-EBI | nuclear chromatin transcription regulatory region sequence-specific DNA binding transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cartilage condensation chondrocyte differentiation DNA-binding transcription factor activity protein binding nucleus transcription by RNA polymerase II positive regulation of chondrocyte differentiation positive regulation of chondrocyte differentiation cell fate commitment negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II cartilage development asymmetric neuroblast division positive regulation of cartilage development cellular response to transforming growth factor beta stimulus positive regulation of mesenchymal stem cell differentiation |
NDEx Network | SOX5 |
Atlas of Cancer Signalling Network | SOX5 |
Wikipedia pathways | SOX5 |
| Orthology - Evolution |
OrthoDB | 6660 |
GeneTree (enSembl) | ENSG00000134532 |
Phylogenetic Trees/Animal Genes : TreeFam | SOX5 |
HOGENOM | P35711 |
Homologs : HomoloGene | SOX5 |
Homology/Alignments : Family Browser (UCSC) | SOX5 |
| Gene fusions - Rearrangements |
Fusion : Mitelman | BICD1/SOX5 [12p11.21/12p12.1]   |
Fusion : Mitelman | CP/SOX5 [3q24/12p12.1]   |
Fusion : Mitelman | KIAA1535/12p12.1 [SOX5/t(12;12)(p11;p12)]   |
Fusion : Mitelman | SOX5/MANSC1 [12p12.1/12p13.2]   |
Fusion Portal | AC011443.1 SOX5 12p12.1 OV |
Fusion Portal | BICD1 12p11.21 SOX5 12p12.1 LGG |
Fusion Portal | C12orf35 SOX5 12p12.1 KIRC |
Fusion Portal | CP 3q24 SOX5 12p12.1 BRCA |
Fusion Portal | SOX5 12p12.1 AC007621.1 LGG |
Fusion Portal | SOX5 12p12.1 MANSC1 12p13.2 LGG |
Fusion Portal | SOX5 12p12.1 RP11-176H8.1 BRCA |
Fusion : Quiver | SOX5 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | SOX5 [hg38] |
dbVar | SOX5 |
ClinVar | SOX5 |
Monarch | SOX5 |
1000_Genomes | SOX5 |
Exome Variant Server | SOX5 |
GNOMAD Browser | ENSG00000134532 |
Varsome Browser | SOX5 |
Genomic Variants (DGV) | SOX5 [DGVbeta] |
DECIPHER | SOX5 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | SOX5 |
| Mutations |
ICGC Data Portal | SOX5 |
TCGA Data Portal | SOX5 |
Broad Tumor Portal | SOX5 |
OASIS Portal | SOX5 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | SOX5 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | SOX5 |
Mutations and Diseases : HGMD | SOX5 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
BioMuta | search SOX5 |
DgiDB (Drug Gene Interaction Database) | SOX5 |
DoCM (Curated mutations) | SOX5 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | SOX5 (select a term) |
intoGen | SOX5 |
Cancer3D | SOX5(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 604975 616803 |
Orphanet | 21461 21460 |
DisGeNET | SOX5 |
Medgen | SOX5 |
Genetic Testing Registry | SOX5
|
NextProt | P35711 [Medical] |
GENETests | SOX5 |
Target Validation | SOX5 |
Huge Navigator |
SOX5 [HugePedia] |
ClinGen | SOX5 |
| Clinical trials, drugs, therapy |
---|
MyCancerGenome | SOX5 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA36038 |
Pharos | P35711 |
Clinical trial | SOX5 |
| Miscellaneous |
---|
canSAR (ICR) | SOX5 (select the gene name) |
Harmonizome | SOX5 |
DataMed Index | SOX5 |
| Probes |
---|
| Litterature |
---|
PubMed | 84 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
EVEX | SOX5 |