Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SOX7 (SRY-box 7)

Identity

Alias_namesSRY (sex determining region Y)-box 7
SRY box 7
Other alias-
HGNC (Hugo) SOX7
LocusID (NCBI) 83595
Atlas_Id 42359
Location 8p23.1  [Link to chromosome band 8p23]
Location_base_pair Starts at 10723768 and ends at 10730574 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ASB13 (10p15.1) / SOX7 (8p23.1)SOX7 (8p23.1) / ITGA3 (17q21.33)SOX7 (8p23.1) / RAB1B (11q13.2)
SOX7 (8p23.1) / SOX7 (8p23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SOX7   18196
Cards
Entrez_Gene (NCBI)SOX7  83595  SRY-box 7
Aliases
GeneCards (Weizmann)SOX7
Ensembl hg19 (Hinxton)ENSG00000171056 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171056 [Gene_View]  chr8:10723768-10730574 [Contig_View]  SOX7 [Vega]
ICGC DataPortalENSG00000171056
TCGA cBioPortalSOX7
AceView (NCBI)SOX7
Genatlas (Paris)SOX7
WikiGenes83595
SOURCE (Princeton)SOX7
Genetics Home Reference (NIH)SOX7
Genomic and cartography
GoldenPath hg38 (UCSC)SOX7  -     chr8:10723768-10730574 -  8p23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SOX7  -     8p23.1   [Description]    (hg19-Feb_2009)
EnsemblSOX7 - 8p23.1 [CytoView hg19]  SOX7 - 8p23.1 [CytoView hg38]
Mapping of homologs : NCBISOX7 [Mapview hg19]  SOX7 [Mapview hg38]
OMIM612202   
Gene and transcription
Genbank (Entrez)AJ409320 AK055556 AK223574 BC004299 BC071947
RefSeq transcript (Entrez)NM_031439
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SOX7
Cluster EST : UnigeneHs.709543 [ NCBI ]
CGAP (NCI)Hs.709543
Alternative Splicing GalleryENSG00000171056
Gene ExpressionSOX7 [ NCBI-GEO ]   SOX7 [ EBI - ARRAY_EXPRESS ]   SOX7 [ SEEK ]   SOX7 [ MEM ]
Gene Expression Viewer (FireBrowse)SOX7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83595
GTEX Portal (Tissue expression)SOX7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BT81   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BT81  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BT81
Splice isoforms : SwissVarQ9BT81
PhosPhoSitePlusQ9BT81
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)    SOX_C (PS51516)   
Domains : Interpro (EBI)HMG_box_dom    Sox7/17/18_central    Sox_C   
Domain families : Pfam (Sanger)HMG_box (PF00505)    Sox17_18_mid (PF12067)   
Domain families : Pfam (NCBI)pfam00505    pfam12067   
Domain families : Smart (EMBL)HMG (SM00398)  
Conserved Domain (NCBI)SOX7
DMDM Disease mutations83595
Blocks (Seattle)SOX7
SuperfamilyQ9BT81
Human Protein AtlasENSG00000171056
Peptide AtlasQ9BT81
HPRD18087
IPIIPI00909880   
Protein Interaction databases
DIP (DOE-UCLA)Q9BT81
IntAct (EBI)Q9BT81
FunCoupENSG00000171056
BioGRIDSOX7
STRING (EMBL)SOX7
ZODIACSOX7
Ontologies - Pathways
QuickGOQ9BT81
Ontology : AmiGOendoderm formation  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  negative regulation of cell proliferation  positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIendoderm formation  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  negative regulation of cell proliferation  positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  regulation of canonical Wnt signaling pathway  
NDEx NetworkSOX7
Atlas of Cancer Signalling NetworkSOX7
Wikipedia pathwaysSOX7
Orthology - Evolution
OrthoDB83595
GeneTree (enSembl)ENSG00000171056
Phylogenetic Trees/Animal Genes : TreeFamSOX7
HOVERGENQ9BT81
HOGENOMQ9BT81
Homologs : HomoloGeneSOX7
Homology/Alignments : Family Browser (UCSC)SOX7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSOX7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SOX7
dbVarSOX7
ClinVarSOX7
1000_GenomesSOX7 
Exome Variant ServerSOX7
ExAC (Exome Aggregation Consortium)SOX7 (select the gene name)
Genetic variants : HAPMAP83595
Genomic Variants (DGV)SOX7 [DGVbeta]
DECIPHERSOX7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSOX7 
Mutations
ICGC Data PortalSOX7 
TCGA Data PortalSOX7 
Broad Tumor PortalSOX7
OASIS PortalSOX7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSOX7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSOX7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SOX7
DgiDB (Drug Gene Interaction Database)SOX7
DoCM (Curated mutations)SOX7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SOX7 (select a term)
intoGenSOX7
Cancer3DSOX7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612202   
Orphanet
MedgenSOX7
Genetic Testing Registry SOX7
NextProtQ9BT81 [Medical]
TSGene83595
GENETestsSOX7
Target ValidationSOX7
Huge Navigator SOX7 [HugePedia]
snp3D : Map Gene to Disease83595
BioCentury BCIQSOX7
ClinGenSOX7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD83595
Chemical/Pharm GKB GenePA38307
Clinical trialSOX7
Miscellaneous
canSAR (ICR)SOX7 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSOX7
EVEXSOX7
GoPubMedSOX7
iHOPSOX7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:32:32 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.