Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SP100 (SP100 nuclear antigen)

Identity

Alias_namesnuclear antigen Sp100
Other aliaslysp100b
HGNC (Hugo) SP100
LocusID (NCBI) 6672
Atlas_Id 46310
Location 2q37.1  [Link to chromosome band 2q37]
Location_base_pair Starts at 230416156 and ends at 230545602 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LUC7L3 (17q21.33) / SP100 (2q37.1)SP100 (2q37.1) / PAX7 (1p36.13)SP100 (2q37.1) / PHLPP2 (16q22.2)
SP100 (2q37.1) / SUCLG1 (2p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SP100   11206
Cards
Entrez_Gene (NCBI)SP100  6672  SP100 nuclear antigen
Aliaseslysp100b
GeneCards (Weizmann)SP100
Ensembl hg19 (Hinxton)ENSG00000067066 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000067066 [Gene_View]  chr2:230416156-230545602 [Contig_View]  SP100 [Vega]
ICGC DataPortalENSG00000067066
TCGA cBioPortalSP100
AceView (NCBI)SP100
Genatlas (Paris)SP100
WikiGenes6672
SOURCE (Princeton)SP100
Genetics Home Reference (NIH)SP100
Genomic and cartography
GoldenPath hg38 (UCSC)SP100  -     chr2:230416156-230545602 +  2q37.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SP100  -     2q37.1   [Description]    (hg19-Feb_2009)
EnsemblSP100 - 2q37.1 [CytoView hg19]  SP100 - 2q37.1 [CytoView hg38]
Mapping of homologs : NCBISP100 [Mapview hg19]  SP100 [Mapview hg38]
OMIM604585   
Gene and transcription
Genbank (Entrez)AA810108 AF056322 AF255565 AI886092 AK090565
RefSeq transcript (Entrez)NM_001080391 NM_001206701 NM_001206702 NM_001206703 NM_001206704 NM_003113
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SP100
Cluster EST : UnigeneHs.369056 [ NCBI ]
CGAP (NCI)Hs.369056
Alternative Splicing GalleryENSG00000067066
Gene ExpressionSP100 [ NCBI-GEO ]   SP100 [ EBI - ARRAY_EXPRESS ]   SP100 [ SEEK ]   SP100 [ MEM ]
Gene Expression Viewer (FireBrowse)SP100 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6672
GTEX Portal (Tissue expression)SP100
Protein : pattern, domain, 3D structure
UniProt/SwissProtP23497   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP23497  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP23497
Splice isoforms : SwissVarP23497
PhosPhoSitePlusP23497
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)    HSR (PS51414)    SAND (PS50864)   
Domains : Interpro (EBI)HMG_box_dom    HSR_dom    SAND_dom    SAND_dom-like   
Domain families : Pfam (Sanger)HMG_box (PF00505)    HMG_box_2 (PF09011)    HSR (PF03172)    SAND (PF01342)   
Domain families : Pfam (NCBI)pfam00505    pfam09011    pfam03172    pfam01342   
Domain families : Smart (EMBL)HMG (SM00398)  SAND (SM00258)  
Conserved Domain (NCBI)SP100
DMDM Disease mutations6672
Blocks (Seattle)SP100
PDB (SRS)1H5P    5FB0    5FB1   
PDB (PDBSum)1H5P    5FB0    5FB1   
PDB (IMB)1H5P    5FB0    5FB1   
PDB (RSDB)1H5P    5FB0    5FB1   
Structural Biology KnowledgeBase1H5P    5FB0    5FB1   
SCOP (Structural Classification of Proteins)1H5P    5FB0    5FB1   
CATH (Classification of proteins structures)1H5P    5FB0    5FB1   
SuperfamilyP23497
Human Protein AtlasENSG00000067066
Peptide AtlasP23497
HPRD06844
IPIIPI00011675   IPI00218324   IPI00218325   IPI00218326   IPI00218327   IPI00916117   IPI00816205   IPI00985149   IPI00917345   IPI00917048   IPI00916851   IPI00917667   IPI00917227   
Protein Interaction databases
DIP (DOE-UCLA)P23497
IntAct (EBI)P23497
FunCoupENSG00000067066
BioGRIDSP100
STRING (EMBL)SP100
ZODIACSP100
Ontologies - Pathways
QuickGOP23497
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  telomere maintenance  nuclear chromosome, telomeric region  DNA binding  transcription coactivator activity  transcription corepressor activity  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator  negative regulation of endothelial cell migration  viral process  nuclear body  PML body  kinase binding  protein domain specific binding  Mre11 complex  response to type I interferon  response to type I interferon  response to interferon-gamma  response to interferon-gamma  protein homodimerization activity  negative regulation of DNA binding  negative regulation of sequence-specific DNA binding transcription factor activity  maintenance of protein location  regulation of angiogenesis  positive regulation of transcription, DNA-templated  negative regulation of protein export from nucleus  negative regulation of cellular component movement  interferon-gamma-mediated signaling pathway  interferon-gamma-mediated signaling pathway  type I interferon signaling pathway  chromo shadow domain binding  regulation of extrinsic apoptotic signaling pathway via death domain receptors  regulation of Fas signaling pathway  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  telomere maintenance  nuclear chromosome, telomeric region  DNA binding  transcription coactivator activity  transcription corepressor activity  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator  negative regulation of endothelial cell migration  viral process  nuclear body  PML body  kinase binding  protein domain specific binding  Mre11 complex  response to type I interferon  response to type I interferon  response to interferon-gamma  response to interferon-gamma  protein homodimerization activity  negative regulation of DNA binding  negative regulation of sequence-specific DNA binding transcription factor activity  maintenance of protein location  regulation of angiogenesis  positive regulation of transcription, DNA-templated  negative regulation of protein export from nucleus  negative regulation of cellular component movement  interferon-gamma-mediated signaling pathway  interferon-gamma-mediated signaling pathway  type I interferon signaling pathway  chromo shadow domain binding  regulation of extrinsic apoptotic signaling pathway via death domain receptors  regulation of Fas signaling pathway  
Pathways : BIOCARTARegulation of transcriptional activity by PML [Genes]   
Pathways : KEGGHerpes simplex infection    Viral carcinogenesis   
NDEx NetworkSP100
Atlas of Cancer Signalling NetworkSP100
Wikipedia pathwaysSP100
Orthology - Evolution
OrthoDB6672
GeneTree (enSembl)ENSG00000067066
Phylogenetic Trees/Animal Genes : TreeFamSP100
HOVERGENP23497
HOGENOMP23497
Homologs : HomoloGeneSP100
Homology/Alignments : Family Browser (UCSC)SP100
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSP100 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SP100
dbVarSP100
ClinVarSP100
1000_GenomesSP100 
Exome Variant ServerSP100
ExAC (Exome Aggregation Consortium)SP100 (select the gene name)
Genetic variants : HAPMAP6672
Genomic Variants (DGV)SP100 [DGVbeta]
DECIPHERSP100 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSP100 
Mutations
ICGC Data PortalSP100 
TCGA Data PortalSP100 
Broad Tumor PortalSP100
OASIS PortalSP100 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSP100  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSP100
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SP100
DgiDB (Drug Gene Interaction Database)SP100
DoCM (Curated mutations)SP100 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SP100 (select a term)
intoGenSP100
Cancer3DSP100(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604585   
Orphanet
MedgenSP100
Genetic Testing Registry SP100
NextProtP23497 [Medical]
TSGene6672
GENETestsSP100
Huge Navigator SP100 [HugePedia]
snp3D : Map Gene to Disease6672
BioCentury BCIQSP100
ClinGenSP100
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6672
Chemical/Pharm GKB GenePA36043
Clinical trialSP100
Miscellaneous
canSAR (ICR)SP100 (select the gene name)
Probes
Litterature
PubMed84 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSP100
EVEXSP100
GoPubMedSP100
iHOPSP100
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:38:38 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.