SP2 (Sp2 transcription factor)

2014-10-01  

Identity

HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 6668
MIM: 601801
HGNC: 11207
Ensembl: ENSG00000167182

Variants:

dbSNP: 6668
ClinVar: 6668
TCGA: ENSG00000167182
COSMIC: SP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167182ENST00000376741Q02086
ENSG00000167182ENST00000613139Q9BRW5
ENSG00000167182ENST00000635868A0A1B0GTK3
ENSG00000167182ENST00000637314A0A1B0GVH1
ENSG00000167182ENST00000637943A0A1B0GV29
ENSG00000167182ENST00000642065A0A286YFJ7

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
170716132006Disruption of an SP2/KLF6 repression complex by SHP is required for farnesoid X receptor-induced endothelial cell migration.35
246233142014miR-638 suppresses cell proliferation in gastric cancer by targeting Sp2.30
198345352009Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.27
196988062009Transcriptional regulation of neutral sphingomyelinase 2 gene expression of a human breast cancer cell line, MCF-7, induced by the anti-cancer drug, daunorubicin.17
157883872005Regulation of expression of the chorionic gonadotropin/luteinizing hormone receptor gene in the human myometrium: involvement of specificity protein-1 (Sp1), Sp3, Sp4, Sp-like proteins, and histone deacetylases.7
194823582009Sp2 regulates interferon-gamma-mediated socs1 gene expression.4
264318792015O-GlcNAc modification of Sp3 and Sp4 transcription factors negatively regulates their transcriptional activities.3
272565742016Expression of human gene coding RORγT receptor depends on the Sp2 transcription factor.3
271283722016Novel Mutation (Gly212Val) in the PS2 Gene Associated with Early-Onset Familial Alzheimer's Disease.1

Citation

Dessen P

SP2 (Sp2 transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-10-01

Online version: http://atlasgeneticsoncology.org/gene/54936/sp2