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SP4 (Sp4 transcription factor)

Identity

Alias_symbol (synonym)SPR-1
HF1B
MGC130008
MGC130009
Other alias
HGNC (Hugo) SP4
LocusID (NCBI) 6671
Atlas_Id 50320
Location 7p15.3  [Link to chromosome band 7p15]
Location_base_pair Starts at 21467689 and ends at 21554151 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SP4 (7p15.3) / GPNMB (7p15.3)SP4 7p15.3 / GPNMB 7p15.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SP4   11209
Cards
Entrez_Gene (NCBI)SP4  6671  Sp4 transcription factor
AliasesHF1B; SPR-1
GeneCards (Weizmann)SP4
Ensembl hg19 (Hinxton)ENSG00000105866 [Gene_View]  chr7:21467689-21554151 [Contig_View]  SP4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000105866 [Gene_View]  chr7:21467689-21554151 [Contig_View]  SP4 [Vega]
ICGC DataPortalENSG00000105866
TCGA cBioPortalSP4
AceView (NCBI)SP4
Genatlas (Paris)SP4
WikiGenes6671
SOURCE (Princeton)SP4
Genetics Home Reference (NIH)SP4
Genomic and cartography
GoldenPath hg19 (UCSC)SP4  -     chr7:21467689-21554151 +  7p15.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SP4  -     7p15.3   [Description]    (hg38-Dec_2013)
EnsemblSP4 - 7p15.3 [CytoView hg19]  SP4 - 7p15.3 [CytoView hg38]
Mapping of homologs : NCBISP4 [Mapview hg19]  SP4 [Mapview hg38]
OMIM600540   
Gene and transcription
Genbank (Entrez)AK289728 AK296749 BC015512 BC109300 BC109301
RefSeq transcript (Entrez)NM_003112
RefSeq genomic (Entrez)NC_000007 NC_018918 NT_007819 NW_004929329
Consensus coding sequences : CCDS (NCBI)SP4
Cluster EST : UnigeneHs.88013 [ NCBI ]
CGAP (NCI)Hs.88013
Alternative Splicing GalleryENSG00000105866
Gene ExpressionSP4 [ NCBI-GEO ]   SP4 [ EBI - ARRAY_EXPRESS ]   SP4 [ SEEK ]   SP4 [ MEM ]
Gene Expression Viewer (FireBrowse)SP4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6671
GTEX Portal (Tissue expression)SP4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02446   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ02446  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ02446
Splice isoforms : SwissVarQ02446
PhosPhoSitePlusQ02446
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Sp1_fam    SP4    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)SP4
DMDM Disease mutations6671
Blocks (Seattle)SP4
SuperfamilyQ02446
Human Protein AtlasENSG00000105866
Peptide AtlasQ02446
HPRD02764
IPIIPI00025805   IPI00910576   IPI00892800   IPI00916744   
Protein Interaction databases
DIP (DOE-UCLA)Q02446
IntAct (EBI)Q02446
FunCoupENSG00000105866
BioGRIDSP4
STRING (EMBL)SP4
ZODIACSP4
Ontologies - Pathways
QuickGOQ02446
Ontology : AmiGORNA polymerase II transcription factor activity, sequence-specific DNA binding  DNA binding  transcription coactivator activity  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  microtubule cytoskeleton  intercellular bridge  metal ion binding  
Ontology : EGO-EBIRNA polymerase II transcription factor activity, sequence-specific DNA binding  DNA binding  transcription coactivator activity  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  microtubule cytoskeleton  intercellular bridge  metal ion binding  
NDEx NetworkSP4
Atlas of Cancer Signalling NetworkSP4
Wikipedia pathwaysSP4
Orthology - Evolution
OrthoDB6671
GeneTree (enSembl)ENSG00000105866
Phylogenetic Trees/Animal Genes : TreeFamSP4
HOVERGENQ02446
HOGENOMQ02446
Homologs : HomoloGeneSP4
Homology/Alignments : Family Browser (UCSC)SP4
Gene fusions - Rearrangements
Fusion : MitelmanSP4/GPNMB [7p15.3/7p15.3]  
Fusion: TCGASP4 7p15.3 GPNMB 7p15.3 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SP4
dbVarSP4
ClinVarSP4
1000_GenomesSP4 
Exome Variant ServerSP4
ExAC (Exome Aggregation Consortium)SP4 (select the gene name)
Genetic variants : HAPMAP6671
Genomic Variants (DGV)SP4 [DGVbeta]
DECIPHER (Syndromes)7:21467689-21554151  ENSG00000105866
CONAN: Copy Number AnalysisSP4 
Mutations
ICGC Data PortalSP4 
TCGA Data PortalSP4 
Broad Tumor PortalSP4
OASIS PortalSP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSP4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSP4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SP4
DgiDB (Drug Gene Interaction Database)SP4
DoCM (Curated mutations)SP4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SP4 (select a term)
intoGenSP4
Cancer3DSP4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600540   
Orphanet
MedgenSP4
Genetic Testing Registry SP4
NextProtQ02446 [Medical]
TSGene6671
GENETestsSP4
Huge Navigator SP4 [HugePedia]
snp3D : Map Gene to Disease6671
BioCentury BCIQSP4
ClinGenSP4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6671
Chemical/Pharm GKB GenePA36046
Clinical trialSP4
Miscellaneous
canSAR (ICR)SP4 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSP4
EVEXSP4
GoPubMedSP4
iHOPSP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:20:30 CEST 2017

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