SPAG16 (sperm associated antigen 16)

2014-11-01  

Identity

HGNC
LOCATION
2q34
LOCUSID
ALIAS
PF20,WDR29
FUSION GENES

Other Information

Locus ID:

NCBI: 79582
MIM: 612173
HGNC: 23225
Ensembl: ENSG00000144451

Variants:

dbSNP: 79582
ClinVar: 79582
TCGA: ENSG00000144451
COSMIC: SPAG16

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144451ENST00000272898A0A0A0MQX0
ENSG00000144451ENST00000331683Q8N0X2
ENSG00000144451ENST00000406979F8WB32
ENSG00000144451ENST00000413312A0A0C4DG20
ENSG00000144451ENST00000420497F8WBY1
ENSG00000144451ENST00000432529Q8N0X2
ENSG00000144451ENST00000440779E9PE90
ENSG00000144451ENST00000447990E7EWV3
ENSG00000144451ENST00000451561H0Y811
ENSG00000144451ENST00000452556F8WBQ0

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
123911652002A sperm-associated WD repeat protein orthologous to Chlamydomonas PF20 associates with Spag6, the mammalian orthologue of Chlamydomonas PF16.29
176997352007A heterozygous mutation disrupting the SPAG16 gene results in biochemical instability of central apparatus components of the human sperm axoneme.15
204631772010Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.15
239562472014Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis.15
250861732014Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis.8
281373122017Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5.1
229631372012Genetic variation in SPAG16 regions encoding the WD40 repeats is not associated with reduced sperm motility and axonemal defects in a population of infertile males.0

Citation

Dessen P

SPAG16 (sperm associated antigen 16)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74102/spag16