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SPAG4 (sperm associated antigen 4)

Identity

Alias_symbol (synonym)SUN4
CT127
Other alias
HGNC (Hugo) SPAG4
LocusID (NCBI) 6676
Atlas_Id 53611
Location 20q11.22  [Link to chromosome band 20q11]
Location_base_pair Starts at 35615884 and ends at 35621094 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARFGAP1 (20q13.33) / SPAG4 (20q11.22)ZBED4 (22q13.33) / SPAG4 (20q11.22)ARFGAP1 20q13.33 / SPAG4 20q11.22
ZBED4 22q13.33 / SPAG4 20q11.22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPAG4   11214
Cards
Entrez_Gene (NCBI)SPAG4  6676  sperm associated antigen 4
AliasesCT127; SUN4
GeneCards (Weizmann)SPAG4
Ensembl hg19 (Hinxton)ENSG00000061656 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000061656 [Gene_View]  chr20:35615884-35621094 [Contig_View]  SPAG4 [Vega]
ICGC DataPortalENSG00000061656
TCGA cBioPortalSPAG4
AceView (NCBI)SPAG4
Genatlas (Paris)SPAG4
WikiGenes6676
SOURCE (Princeton)SPAG4
Genetics Home Reference (NIH)SPAG4
Genomic and cartography
GoldenPath hg38 (UCSC)SPAG4  -     chr20:35615884-35621094 +  20q11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPAG4  -     20q11.22   [Description]    (hg19-Feb_2009)
EnsemblSPAG4 - 20q11.22 [CytoView hg19]  SPAG4 - 20q11.22 [CytoView hg38]
Mapping of homologs : NCBISPAG4 [Mapview hg19]  SPAG4 [Mapview hg38]
OMIM603038   
Gene and transcription
Genbank (Entrez)AF262992 AI168233 BC111378 BC143783 HY021678
RefSeq transcript (Entrez)NM_001317931 NM_003116
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPAG4
Cluster EST : UnigeneHs.123159 [ NCBI ]
CGAP (NCI)Hs.123159
Alternative Splicing GalleryENSG00000061656
Gene ExpressionSPAG4 [ NCBI-GEO ]   SPAG4 [ EBI - ARRAY_EXPRESS ]   SPAG4 [ SEEK ]   SPAG4 [ MEM ]
Gene Expression Viewer (FireBrowse)SPAG4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6676
GTEX Portal (Tissue expression)SPAG4
Human Protein AtlasENSG00000061656-SPAG4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NPE6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NPE6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NPE6
Splice isoforms : SwissVarQ9NPE6
PhosPhoSitePlusQ9NPE6
Domaine pattern : Prosite (Expaxy)SUN (PS51469)   
Domains : Interpro (EBI)SPAG4/SUN4    SUN_dom   
Domain families : Pfam (Sanger)Sad1_UNC (PF07738)   
Domain families : Pfam (NCBI)pfam07738   
Conserved Domain (NCBI)SPAG4
DMDM Disease mutations6676
Blocks (Seattle)SPAG4
SuperfamilyQ9NPE6
Human Protein Atlas [tissue]ENSG00000061656-SPAG4 [tissue]
Peptide AtlasQ9NPE6
HPRD04330
IPIIPI00018258   IPI00552666   IPI00916774   
Protein Interaction databases
DIP (DOE-UCLA)Q9NPE6
IntAct (EBI)Q9NPE6
FunCoupENSG00000061656
BioGRIDSPAG4
STRING (EMBL)SPAG4
ZODIACSPAG4
Ontologies - Pathways
QuickGOQ9NPE6
Ontology : AmiGOstructural molecule activity  protein binding  nuclear envelope  nuclear inner membrane  cytoplasm  cytoskeleton  nuclear envelope organization  spermatogenesis  integral component of membrane  cell differentiation  motile cilium  cytoskeletal anchoring at nuclear membrane  
Ontology : EGO-EBIstructural molecule activity  protein binding  nuclear envelope  nuclear inner membrane  cytoplasm  cytoskeleton  nuclear envelope organization  spermatogenesis  integral component of membrane  cell differentiation  motile cilium  cytoskeletal anchoring at nuclear membrane  
NDEx NetworkSPAG4
Atlas of Cancer Signalling NetworkSPAG4
Wikipedia pathwaysSPAG4
Orthology - Evolution
OrthoDB6676
GeneTree (enSembl)ENSG00000061656
Phylogenetic Trees/Animal Genes : TreeFamSPAG4
HOVERGENQ9NPE6
HOGENOMQ9NPE6
Homologs : HomoloGeneSPAG4
Homology/Alignments : Family Browser (UCSC)SPAG4
Gene fusions - Rearrangements
Fusion : MitelmanARFGAP1/SPAG4 [20q13.33/20q11.22]  [t(20;20)(q11;q13)]  
Fusion : MitelmanZBED4/SPAG4 [22q13.33/20q11.22]  [t(20;22)(q11;q13)]  
Fusion: TCGA_MDACCARFGAP1 20q13.33 SPAG4 20q11.22 BRCA
Fusion: TCGA_MDACCZBED4 22q13.33 SPAG4 20q11.22 BRCA
Tumor Fusion PortalSPAG4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPAG4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPAG4
dbVarSPAG4
ClinVarSPAG4
1000_GenomesSPAG4 
Exome Variant ServerSPAG4
ExAC (Exome Aggregation Consortium)ENSG00000061656
GNOMAD BrowserENSG00000061656
Genetic variants : HAPMAP6676
Genomic Variants (DGV)SPAG4 [DGVbeta]
DECIPHERSPAG4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPAG4 
Mutations
ICGC Data PortalSPAG4 
TCGA Data PortalSPAG4 
Broad Tumor PortalSPAG4
OASIS PortalSPAG4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPAG4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPAG4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPAG4
DgiDB (Drug Gene Interaction Database)SPAG4
DoCM (Curated mutations)SPAG4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPAG4 (select a term)
intoGenSPAG4
Cancer3DSPAG4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603038   
Orphanet
DisGeNETSPAG4
MedgenSPAG4
Genetic Testing Registry SPAG4
NextProtQ9NPE6 [Medical]
TSGene6676
GENETestsSPAG4
Target ValidationSPAG4
Huge Navigator SPAG4 [HugePedia]
snp3D : Map Gene to Disease6676
BioCentury BCIQSPAG4
ClinGenSPAG4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6676
Chemical/Pharm GKB GenePA36050
Clinical trialSPAG4
Miscellaneous
canSAR (ICR)SPAG4 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPAG4
EVEXSPAG4
GoPubMedSPAG4
iHOPSPAG4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:36:06 CET 2017

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