SPAG4 (sperm associated antigen 4)

2013-11-01  

Identity

HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
CT127,SUN4
FUSION GENES

Other Information

Locus ID:

NCBI: 6676
MIM: 603038
HGNC: 11214
Ensembl: ENSG00000061656

Variants:

dbSNP: 6676
ClinVar: 6676
TCGA: ENSG00000061656
COSMIC: SPAG4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000061656ENST00000374273Q9NPE6
ENSG00000061656ENST00000430878Q5JX49
ENSG00000061656ENST00000454819C9JJZ6

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
236028312013Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma.8
238183242014Hypoxia regulates the sperm associated antigen 4 (SPAG4) via HIF, which is expressed in renal clear cell carcinoma and promotes migration and invasion in vitro.6
299011142018Sperm‑associated antigen 4 (SPAG4) as a new cancer marker interacts with Nesprin3 to regulate cell migration in lung carcinoma.1
311447112019SPAG4L/SPAG4Lβ interacts with Nesprin2 to participate in the meiosis of spermatogenesis.1
308176822019Human sperm-associated antigen 4 as a potential biomarker of glioblastoma progression and prognosis.0

Citation

Dessen P

SPAG4 (sperm associated antigen 4)

Atlas Genet Cytogenet Oncol Haematol. 2013-11-01

Online version: http://atlasgeneticsoncology.org/gene/53611/spag4