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SPAG5 (sperm associated antigen 5)

Identity

Alias_symbol (synonym)DEEPEST
MAP126
hMAP126
Other alias
HGNC (Hugo) SPAG5
LocusID (NCBI) 10615
Atlas_Id 54948
Location 17q11.2  [Link to chromosome band 17q11]
Location_base_pair Starts at 26904583 and ends at 26926056 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CDC42BPB (14q32.32) / SPAG5 (17q11.2)PIGS (17q11.2) / SPAG5 (17q11.2)PPM1E (17q22) / SPAG5 (17q11.2)
SPAG5 (17q11.2) / BLMH (17q11.2)SPAG5 (17q11.2) / SLC47A1 (17p11.2)SPAG5 (17q11.2) / SPAG5 (17q11.2)
PIGS 17q11.2 / SPAG5 17q11.2PPM1E 17q22 / SPAG5 17q11.2SPAG5 17q11.2 / BLMH 17q11.2
SPAG5 17q11.2 / SLC47A1 17p11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPAG5   13452
Cards
Entrez_Gene (NCBI)SPAG5  10615  sperm associated antigen 5
AliasesDEEPEST; MAP126; hMAP126
GeneCards (Weizmann)SPAG5
Ensembl hg19 (Hinxton)ENSG00000076382 [Gene_View]  chr17:26904583-26926056 [Contig_View]  SPAG5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000076382 [Gene_View]  chr17:26904583-26926056 [Contig_View]  SPAG5 [Vega]
ICGC DataPortalENSG00000076382
TCGA cBioPortalSPAG5
AceView (NCBI)SPAG5
Genatlas (Paris)SPAG5
WikiGenes10615
SOURCE (Princeton)SPAG5
Genetics Home Reference (NIH)SPAG5
Genomic and cartography
GoldenPath hg19 (UCSC)SPAG5  -     chr17:26904583-26926056 -  17q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SPAG5  -     17q11.2   [Description]    (hg38-Dec_2013)
EnsemblSPAG5 - 17q11.2 [CytoView hg19]  SPAG5 - 17q11.2 [CytoView hg38]
Mapping of homologs : NCBISPAG5 [Mapview hg19]  SPAG5 [Mapview hg38]
OMIM615562   
Gene and transcription
Genbank (Entrez)AF063308 AF345347 AF399910 AK025725 AK292398
RefSeq transcript (Entrez)NM_006461
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)SPAG5
Cluster EST : UnigeneHs.514033 [ NCBI ]
CGAP (NCI)Hs.514033
Alternative Splicing GalleryENSG00000076382
Gene ExpressionSPAG5 [ NCBI-GEO ]   SPAG5 [ EBI - ARRAY_EXPRESS ]   SPAG5 [ SEEK ]   SPAG5 [ MEM ]
Gene Expression Viewer (FireBrowse)SPAG5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10615
GTEX Portal (Tissue expression)SPAG5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96R06   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96R06  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96R06
Splice isoforms : SwissVarQ96R06
PhosPhoSitePlusQ96R06
Domains : Interpro (EBI)Astrin   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)SPAG5
DMDM Disease mutations10615
Blocks (Seattle)SPAG5
SuperfamilyQ96R06
Human Protein AtlasENSG00000076382
Peptide AtlasQ96R06
HPRD10246
IPIIPI00328118   IPI01013144   
Protein Interaction databases
DIP (DOE-UCLA)Q96R06
IntAct (EBI)Q96R06
FunCoupENSG00000076382
BioGRIDSPAG5
STRING (EMBL)SPAG5
ZODIACSPAG5
Ontologies - Pathways
QuickGOQ96R06
Ontology : AmiGOmitotic sister chromatid segregation  kinetochore  condensed chromosome kinetochore  spindle pole  protein binding  nucleus  nucleoplasm  cytoplasm  spindle microtubule  spindle organization  chromosome segregation  midbody  centriolar satellite  microtubule plus-end  establishment of spindle orientation  cell division  regulation of attachment of spindle microtubules to kinetochore  protein localization to centrosome  mitotic spindle  
Ontology : EGO-EBImitotic sister chromatid segregation  kinetochore  condensed chromosome kinetochore  spindle pole  protein binding  nucleus  nucleoplasm  cytoplasm  spindle microtubule  spindle organization  chromosome segregation  midbody  centriolar satellite  microtubule plus-end  establishment of spindle orientation  cell division  regulation of attachment of spindle microtubules to kinetochore  protein localization to centrosome  mitotic spindle  
NDEx NetworkSPAG5
Atlas of Cancer Signalling NetworkSPAG5
Wikipedia pathwaysSPAG5
Orthology - Evolution
OrthoDB10615
GeneTree (enSembl)ENSG00000076382
Phylogenetic Trees/Animal Genes : TreeFamSPAG5
HOVERGENQ96R06
HOGENOMQ96R06
Homologs : HomoloGeneSPAG5
Homology/Alignments : Family Browser (UCSC)SPAG5
Gene fusions - Rearrangements
Fusion : MitelmanPIGS/SPAG5 [17q11.2/17q11.2]  [t(17;17)(q11;q11)]  
Fusion : MitelmanPPM1E/SPAG5 [17q22/17q11.2]  [t(17;17)(q11;q22)]  
Fusion : MitelmanSPAG5/BLMH [17q11.2/17q11.2]  [t(17;17)(q11;q11)]  
Fusion : MitelmanSPAG5/SLC47A1 [17q11.2/17p11.2]  [t(17;17)(p11;q11)]  
Fusion: TCGAPIGS 17q11.2 SPAG5 17q11.2 OV
Fusion: TCGAPPM1E 17q22 SPAG5 17q11.2 BRCA
Fusion: TCGASPAG5 17q11.2 BLMH 17q11.2 BRCA
Fusion: TCGASPAG5 17q11.2 SLC47A1 17p11.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPAG5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPAG5
dbVarSPAG5
ClinVarSPAG5
1000_GenomesSPAG5 
Exome Variant ServerSPAG5
ExAC (Exome Aggregation Consortium)SPAG5 (select the gene name)
Genetic variants : HAPMAP10615
Genomic Variants (DGV)SPAG5 [DGVbeta]
DECIPHER (Syndromes)17:26904583-26926056  ENSG00000076382
CONAN: Copy Number AnalysisSPAG5 
Mutations
ICGC Data PortalSPAG5 
TCGA Data PortalSPAG5 
Broad Tumor PortalSPAG5
OASIS PortalSPAG5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPAG5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPAG5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPAG5
DgiDB (Drug Gene Interaction Database)SPAG5
DoCM (Curated mutations)SPAG5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPAG5 (select a term)
intoGenSPAG5
Cancer3DSPAG5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615562   
Orphanet
MedgenSPAG5
Genetic Testing Registry SPAG5
NextProtQ96R06 [Medical]
TSGene10615
GENETestsSPAG5
Huge Navigator SPAG5 [HugePedia]
snp3D : Map Gene to Disease10615
BioCentury BCIQSPAG5
ClinGenSPAG5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10615
Chemical/Pharm GKB GenePA134868542
Clinical trialSPAG5
Miscellaneous
canSAR (ICR)SPAG5 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPAG5
EVEXSPAG5
GoPubMedSPAG5
iHOPSPAG5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:28:46 CET 2017

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