Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SPAG6 (sperm associated antigen 6)

Identity

Alias_symbol (synonym)Repro-SA-1
pf16
CT141
Other alias
HGNC (Hugo) SPAG6
LocusID (NCBI) 9576
Atlas_Id 55971
Location 10p12.2  [Link to chromosome band 10p12]
Location_base_pair Starts at 22345445 and ends at 22417610 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AGBL4 (1p33) / SPAG6 (10p12.2)GFM2 (5q13.3) / SPAG6 (10p12.2)KIAA1217 (10p12.2) / SPAG6 (10p12.2)
SPAG6 (10p12.2) / PLXDC2 (10p12.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  KIAA1217/SPAG6 (10p12)
SPAG6/PLXDC2 (10p12)


External links

Nomenclature
HGNC (Hugo)SPAG6   11215
Cards
Entrez_Gene (NCBI)SPAG6  9576  sperm associated antigen 6
AliasesCT141; Repro-SA-1; pf16
GeneCards (Weizmann)SPAG6
Ensembl hg19 (Hinxton)ENSG00000077327 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000077327 [Gene_View]  ENSG00000077327 [Sequence]  chr10:22345445-22417610 [Contig_View]  SPAG6 [Vega]
ICGC DataPortalENSG00000077327
TCGA cBioPortalSPAG6
AceView (NCBI)SPAG6
Genatlas (Paris)SPAG6
WikiGenes9576
SOURCE (Princeton)SPAG6
Genetics Home Reference (NIH)SPAG6
Genomic and cartography
GoldenPath hg38 (UCSC)SPAG6  -     chr10:22345445-22417610 +  10p12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPAG6  -     10p12.2   [Description]    (hg19-Feb_2009)
EnsemblSPAG6 - 10p12.2 [CytoView hg19]  SPAG6 - 10p12.2 [CytoView hg38]
Mapping of homologs : NCBISPAG6 [Mapview hg19]  SPAG6 [Mapview hg38]
OMIM605730   
Gene and transcription
Genbank (Entrez)AF079363 AK289903 AK302194 AK310247 AL080136
RefSeq transcript (Entrez)NM_001253854 NM_001253855 NM_012443 NM_172242
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPAG6
Cluster EST : UnigeneHs.655170 [ NCBI ]
CGAP (NCI)Hs.655170
Alternative Splicing GalleryENSG00000077327
Gene ExpressionSPAG6 [ NCBI-GEO ]   SPAG6 [ EBI - ARRAY_EXPRESS ]   SPAG6 [ SEEK ]   SPAG6 [ MEM ]
Gene Expression Viewer (FireBrowse)SPAG6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9576
GTEX Portal (Tissue expression)SPAG6
Human Protein AtlasENSG00000077327-SPAG6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75602   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75602  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75602
Splice isoforms : SwissVarO75602
PhosPhoSitePlusO75602
Domains : Interpro (EBI)ARM-like    ARM-type_fold    Armadillo   
Domain families : Pfam (Sanger)Arm (PF00514)   
Domain families : Pfam (NCBI)pfam00514   
Domain families : Smart (EMBL)ARM (SM00185)  
Conserved Domain (NCBI)SPAG6
DMDM Disease mutations9576
Blocks (Seattle)SPAG6
SuperfamilyO75602
Human Protein Atlas [tissue]ENSG00000077327-SPAG6 [tissue]
Peptide AtlasO75602
HPRD09305
IPIIPI00220580   IPI00335443   IPI00479375   IPI00479710   IPI01015156   
Protein Interaction databases
DIP (DOE-UCLA)O75602
IntAct (EBI)O75602
FunCoupENSG00000077327
BioGRIDSPAG6
STRING (EMBL)SPAG6
ZODIACSPAG6
Ontologies - Pathways
QuickGOO75602
Ontology : AmiGOnucleus  microtubule  axoneme  spermatid development  microtubule cytoskeleton  cell projection organization  motile cilium  
Ontology : EGO-EBInucleus  microtubule  axoneme  spermatid development  microtubule cytoskeleton  cell projection organization  motile cilium  
NDEx NetworkSPAG6
Atlas of Cancer Signalling NetworkSPAG6
Wikipedia pathwaysSPAG6
Orthology - Evolution
OrthoDB9576
GeneTree (enSembl)ENSG00000077327
Phylogenetic Trees/Animal Genes : TreeFamSPAG6
HOVERGENO75602
HOGENOMO75602
Homologs : HomoloGeneSPAG6
Homology/Alignments : Family Browser (UCSC)SPAG6
Gene fusions - Rearrangements
Fusion : QuiverSPAG6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPAG6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPAG6
dbVarSPAG6
ClinVarSPAG6
1000_GenomesSPAG6 
Exome Variant ServerSPAG6
ExAC (Exome Aggregation Consortium)ENSG00000077327
GNOMAD BrowserENSG00000077327
Varsome BrowserSPAG6
Genetic variants : HAPMAP9576
Genomic Variants (DGV)SPAG6 [DGVbeta]
DECIPHERSPAG6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPAG6 
Mutations
ICGC Data PortalSPAG6 
TCGA Data PortalSPAG6 
Broad Tumor PortalSPAG6
OASIS PortalSPAG6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPAG6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPAG6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPAG6
DgiDB (Drug Gene Interaction Database)SPAG6
DoCM (Curated mutations)SPAG6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPAG6 (select a term)
intoGenSPAG6
Cancer3DSPAG6(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605730   
Orphanet
DisGeNETSPAG6
MedgenSPAG6
Genetic Testing Registry SPAG6
NextProtO75602 [Medical]
TSGene9576
GENETestsSPAG6
Target ValidationSPAG6
Huge Navigator SPAG6 [HugePedia]
snp3D : Map Gene to Disease9576
BioCentury BCIQSPAG6
ClinGenSPAG6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9576
Chemical/Pharm GKB GenePA36051
Clinical trialSPAG6
Miscellaneous
canSAR (ICR)SPAG6 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPAG6
EVEXSPAG6
GoPubMedSPAG6
iHOPSPAG6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:41:21 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.