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SPARCL1 (SPARC like 1)

Identity

Alias_namesSPARC-like 1 (mast9
Alias_symbol (synonym)MAST9
Other aliasMAST 9
PIG33
SC1
HGNC (Hugo) SPARCL1
LocusID (NCBI) 8404
Atlas_Id 42370
Location 4q22.1  [Link to chromosome band 4q22]
Location_base_pair Starts at 88394482 and ends at 88450655 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BBX (3q13.12) / SPARCL1 (4q22.1)CACNB2 (10p12.33) / SPARCL1 (4q22.1)MED10 (5p15.31) / SPARCL1 (4q22.1)
PPP3CA (4q24) / SPARCL1 (4q22.1)SPARCL1 (4q22.1) / GBAS (7p11.2)SPARCL1 (4q22.1) / NCALD (8q22.3)
SPARCL1 (4q22.1) / PKP4 (2q24.1)SPARCL1 (4q22.1) / SEC63 (6q21)SPARCL1 (4q22.1) / SGSM1 (22q11.23)
SPARCL1 (4q22.1) / SPARCL1 (4q22.1)SPARCL1 (4q22.1) / SYNPR (3p14.2)SPARCL1 (4q22.1) / ZNF713 (7p11.2)
SSFA2 (2q31.3) / SPARCL1 (4q22.1)PPP3CA 4q24 / SPARCL1 4q22.1SPARCL1 4q22.1 / NCALD 8q22.3
SPARCL1 4q22.1 / SEC63 6q21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPARCL1   11220
Cards
Entrez_Gene (NCBI)SPARCL1  8404  SPARC like 1
AliasesMAST; MAST9; PIG33; SC1
GeneCards (Weizmann)SPARCL1
Ensembl hg19 (Hinxton)ENSG00000152583 [Gene_View]  chr4:88394482-88450655 [Contig_View]  SPARCL1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000152583 [Gene_View]  chr4:88394482-88450655 [Contig_View]  SPARCL1 [Vega]
ICGC DataPortalENSG00000152583
TCGA cBioPortalSPARCL1
AceView (NCBI)SPARCL1
Genatlas (Paris)SPARCL1
WikiGenes8404
SOURCE (Princeton)SPARCL1
Genetics Home Reference (NIH)SPARCL1
Genomic and cartography
GoldenPath hg19 (UCSC)SPARCL1  -     chr4:88394482-88450655 -  4q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SPARCL1  -     4q22.1   [Description]    (hg38-Dec_2013)
EnsemblSPARCL1 - 4q22.1 [CytoView hg19]  SPARCL1 - 4q22.1 [CytoView hg38]
Mapping of homologs : NCBISPARCL1 [Mapview hg19]  SPARCL1 [Mapview hg38]
OMIM606041   
Gene and transcription
Genbank (Entrez)AK294335 AK298039 AK300956 AK304494 AK304628
RefSeq transcript (Entrez)NM_001128310 NM_001291976 NM_001291977 NM_004684
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)SPARCL1
Cluster EST : UnigeneHs.62886 [ NCBI ]
CGAP (NCI)Hs.62886
Alternative Splicing GalleryENSG00000152583
Gene ExpressionSPARCL1 [ NCBI-GEO ]   SPARCL1 [ EBI - ARRAY_EXPRESS ]   SPARCL1 [ SEEK ]   SPARCL1 [ MEM ]
Gene Expression Viewer (FireBrowse)SPARCL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8404
GTEX Portal (Tissue expression)SPARCL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14515   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14515  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14515
Splice isoforms : SwissVarQ14515
PhosPhoSitePlusQ14515
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)    KAZAL_2 (PS51465)    OSTEONECTIN_1 (PS00612)    OSTEONECTIN_2 (PS00613)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    Fol_N    Follistatin/Osteonectin_EGF    Kazal_dom    Osteonectin_CS    SPARC-like_p1    SPARC/Testican_Ca-bd-dom   
Domain families : Pfam (Sanger)FOLN (PF09289)    Kazal_1 (PF00050)    SPARC_Ca_bdg (PF10591)   
Domain families : Pfam (NCBI)pfam09289    pfam00050    pfam10591   
Domain families : Smart (EMBL)FOLN (SM00274)  KAZAL (SM00280)  
Conserved Domain (NCBI)SPARCL1
DMDM Disease mutations8404
Blocks (Seattle)SPARCL1
SuperfamilyQ14515
Human Protein AtlasENSG00000152583
Peptide AtlasQ14515
HPRD06919
IPIIPI00296777   IPI00910380   IPI00910886   IPI00909737   IPI00793166   IPI01016044   IPI01018741   IPI00965611   IPI01009630   IPI01010548   
Protein Interaction databases
DIP (DOE-UCLA)Q14515
IntAct (EBI)Q14515
FunCoupENSG00000152583
BioGRIDSPARCL1
STRING (EMBL)SPARCL1
ZODIACSPARCL1
Ontologies - Pathways
QuickGOQ14515
Ontology : AmiGOcalcium ion binding  proteinaceous extracellular matrix  extracellular space  signal transduction  extracellular exosome  
Ontology : EGO-EBIcalcium ion binding  proteinaceous extracellular matrix  extracellular space  signal transduction  extracellular exosome  
NDEx NetworkSPARCL1
Atlas of Cancer Signalling NetworkSPARCL1
Wikipedia pathwaysSPARCL1
Orthology - Evolution
OrthoDB8404
GeneTree (enSembl)ENSG00000152583
Phylogenetic Trees/Animal Genes : TreeFamSPARCL1
HOVERGENQ14515
HOGENOMQ14515
Homologs : HomoloGeneSPARCL1
Homology/Alignments : Family Browser (UCSC)SPARCL1
Gene fusions - Rearrangements
Fusion : MitelmanPPP3CA/SPARCL1 [4q24/4q22.1]  [t(4;4)(q22;q24)]  
Fusion : MitelmanSPARCL1/NCALD [4q22.1/8q22.3]  [t(4;8)(q22;q22)]  
Fusion : MitelmanSPARCL1/SEC63 [4q22.1/6q21]  [t(4;6)(q22;q21)]  
Fusion: TCGAPPP3CA 4q24 SPARCL1 4q22.1 BRCA
Fusion: TCGASPARCL1 4q22.1 NCALD 8q22.3 LGG
Fusion: TCGASPARCL1 4q22.1 SEC63 6q21 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPARCL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPARCL1
dbVarSPARCL1
ClinVarSPARCL1
1000_GenomesSPARCL1 
Exome Variant ServerSPARCL1
ExAC (Exome Aggregation Consortium)SPARCL1 (select the gene name)
Genetic variants : HAPMAP8404
Genomic Variants (DGV)SPARCL1 [DGVbeta]
DECIPHER (Syndromes)4:88394482-88450655  ENSG00000152583
CONAN: Copy Number AnalysisSPARCL1 
Mutations
ICGC Data PortalSPARCL1 
TCGA Data PortalSPARCL1 
Broad Tumor PortalSPARCL1
OASIS PortalSPARCL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPARCL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPARCL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPARCL1
DgiDB (Drug Gene Interaction Database)SPARCL1
DoCM (Curated mutations)SPARCL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPARCL1 (select a term)
intoGenSPARCL1
Cancer3DSPARCL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606041   
Orphanet
MedgenSPARCL1
Genetic Testing Registry SPARCL1
NextProtQ14515 [Medical]
TSGene8404
GENETestsSPARCL1
Huge Navigator SPARCL1 [HugePedia]
snp3D : Map Gene to Disease8404
BioCentury BCIQSPARCL1
ClinGenSPARCL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8404
Chemical/Pharm GKB GenePA36056
Clinical trialSPARCL1
Miscellaneous
canSAR (ICR)SPARCL1 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPARCL1
EVEXSPARCL1
GoPubMedSPARCL1
iHOPSPARCL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:20:33 CEST 2017

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