Identity
HGNC
LOCATION
13q12.12
LOCUSID
ALIAS
ARHGEF29,ASEF2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 221178
MIM: 613324
HGNC: 23222
Ensembl: ENSG00000273167
Variants:
dbSNP: 221178
ClinVar: 221178
TCGA: ENSG00000273167
COSMIC: SPATA13
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000273167 | ENST00000382141 | A0A0A0MRY4 |
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Regulation of actin cytoskeleton | KEGG | ko04810 |
| Regulation of actin cytoskeleton | KEGG | hsa04810 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32339198 | 2020 | Mutations in SPATA13/ASEF2 cause primary angle closure glaucoma. | 7 |
| 32339198 | 2020 | Mutations in SPATA13/ASEF2 cause primary angle closure glaucoma. | 7 |
| 24874604 | 2014 | Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover. | 3 |
| 24874604 | 2014 | Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover. | 3 |
| 24144700 | 2013 | Activation of Rac by Asef2 promotes myosin II-dependent contractility to inhibit cell migration on type I collagen. | 15 |
| 24144700 | 2013 | Activation of Rac by Asef2 promotes myosin II-dependent contractility to inhibit cell migration on type I collagen. | 15 |
| 19910543 | 2010 | Confirmation of genomewide association signals in Chinese Han population reveals risk loci for ischemic stroke. | 7 |
| 19910543 | 2010 | Confirmation of genomewide association signals in Chinese Han population reveals risk loci for ischemic stroke. | 7 |
| 19151759 | 2009 | Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration. | 19 |
| 19934221 | 2009 | The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration. | 36 |
| 19151759 | 2009 | Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration. | 19 |
| 19934221 | 2009 | The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration. | 36 |
| 17599059 | 2007 | Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42. | 41 |
| 17599059 | 2007 | Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42. | 41 |
Citation
Dessen P
SPATA13 (spermatogenesis associated 13)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43501/spata13
