Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9825
MIM: 607662
HGNC: 14681
Ensembl: ENSG00000158480
Variants:
dbSNP: 9825
ClinVar: 9825
TCGA: ENSG00000158480
COSMIC: SPATA2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000158480 | ENST00000289431 | Q9UM82 |
| ENSG00000158480 | ENST00000422556 | Q9UM82 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30697874 | 2019 | Tumor necrosis factor receptor modulator spermatogenesis-associated protein 2 is a novel predictor of outcome in ovarian cancer. | 7 |
| 30697874 | 2019 | Tumor necrosis factor receptor modulator spermatogenesis-associated protein 2 is a novel predictor of outcome in ovarian cancer. | 7 |
| 27307491 | 2016 | SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes. | 85 |
| 27458237 | 2016 | SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death. | 63 |
| 27545878 | 2016 | SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. | 74 |
| 27591049 | 2016 | SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling. | 83 |
| 27307491 | 2016 | SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes. | 85 |
| 27458237 | 2016 | SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death. | 63 |
| 27545878 | 2016 | SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. | 74 |
| 27591049 | 2016 | SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling. | 83 |
| 25093496 | 2014 | PD-1(+) CD8(+) T cells are exhausted in tumours and functional in draining lymph nodes of colorectal cancer patients. | 60 |
| 25264125 | 2014 | Investigating the genetic association of HCP5, SPATA2, TNIP1, TNFAIP3 and COG6 with psoriasis in Chinese population. | 9 |
| 25093496 | 2014 | PD-1(+) CD8(+) T cells are exhausted in tumours and functional in draining lymph nodes of colorectal cancer patients. | 60 |
| 25264125 | 2014 | Investigating the genetic association of HCP5, SPATA2, TNIP1, TNFAIP3 and COG6 with psoriasis in Chinese population. | 9 |
| 20385810 | 2010 | Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer. | 452 |
Citation
Dessen P
SPATA2 (spermatogenesis associated 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-06-01
Online version: http://atlasgeneticsoncology.org/gene/51535/spata2
