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SPC24 (SPC24, NDC80 kinetochore complex component)

Identity

Alias_namesSPBC24
spindle pole body component 24 homolog (S. cerevisiae)
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
Alias_symbol (synonym)FLJ90806
Other alias
HGNC (Hugo) SPC24
LocusID (NCBI) 147841
Atlas_Id 56627
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 11145494 and ends at 11155812 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KANK3 (19p13.2) / SPC24 (19p13.2)SPC24 (19p13.2) / KANK2 (19p13.2)SPC24 (19p13.2) / RACK1 (5q35.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPC24   26913
Cards
Entrez_Gene (NCBI)SPC24  147841  SPC24, NDC80 kinetochore complex component
AliasesSPBC24
GeneCards (Weizmann)SPC24
Ensembl hg19 (Hinxton)ENSG00000161888 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000161888 [Gene_View]  chr19:11145494-11155812 [Contig_View]  SPC24 [Vega]
ICGC DataPortalENSG00000161888
TCGA cBioPortalSPC24
AceView (NCBI)SPC24
Genatlas (Paris)SPC24
WikiGenes147841
SOURCE (Princeton)SPC24
Genetics Home Reference (NIH)SPC24
Genomic and cartography
GoldenPath hg38 (UCSC)SPC24  -     chr19:11145494-11155812 -  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPC24  -     19p13.2   [Description]    (hg19-Feb_2009)
EnsemblSPC24 - 19p13.2 [CytoView hg19]  SPC24 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBISPC24 [Mapview hg19]  SPC24 [Mapview hg38]
OMIM609394   
Gene and transcription
Genbank (Entrez)AK075287 AK303157 AK303266 AY456387 BC105037
RefSeq transcript (Entrez)NM_001317031 NM_001317032 NM_001317033 NM_182513
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPC24
Cluster EST : UnigeneHs.736069 [ NCBI ]
CGAP (NCI)Hs.736069
Alternative Splicing GalleryENSG00000161888
Gene ExpressionSPC24 [ NCBI-GEO ]   SPC24 [ EBI - ARRAY_EXPRESS ]   SPC24 [ SEEK ]   SPC24 [ MEM ]
Gene Expression Viewer (FireBrowse)SPC24 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)147841
GTEX Portal (Tissue expression)SPC24
Human Protein AtlasENSG00000161888-SPC24 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NBT2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NBT2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NBT2
Splice isoforms : SwissVarQ8NBT2
PhosPhoSitePlusQ8NBT2
Domains : Interpro (EBI)Ndc80_Spc24   
Domain families : Pfam (Sanger)Spc24 (PF08286)   
Domain families : Pfam (NCBI)pfam08286   
Conserved Domain (NCBI)SPC24
DMDM Disease mutations147841
Blocks (Seattle)SPC24
PDB (SRS)2VE7    3IZ0   
PDB (PDBSum)2VE7    3IZ0   
PDB (IMB)2VE7    3IZ0   
PDB (RSDB)2VE7    3IZ0   
Structural Biology KnowledgeBase2VE7    3IZ0   
SCOP (Structural Classification of Proteins)2VE7    3IZ0   
CATH (Classification of proteins structures)2VE7    3IZ0   
SuperfamilyQ8NBT2
Human Protein Atlas [tissue]ENSG00000161888-SPC24 [tissue]
Peptide AtlasQ8NBT2
HPRD15464
IPIIPI00168317   IPI00908328   
Protein Interaction databases
DIP (DOE-UCLA)Q8NBT2
IntAct (EBI)Q8NBT2
FunCoupENSG00000161888
BioGRIDSPC24
STRING (EMBL)SPC24
ZODIACSPC24
Ontologies - Pathways
QuickGOQ8NBT2
Ontology : AmiGOcondensed chromosome kinetochore  protein binding  nucleus  nucleolus  cytosol  sister chromatid cohesion  Ndc80 complex  cell division  
Ontology : EGO-EBIcondensed chromosome kinetochore  protein binding  nucleus  nucleolus  cytosol  sister chromatid cohesion  Ndc80 complex  cell division  
NDEx NetworkSPC24
Atlas of Cancer Signalling NetworkSPC24
Wikipedia pathwaysSPC24
Orthology - Evolution
OrthoDB147841
GeneTree (enSembl)ENSG00000161888
Phylogenetic Trees/Animal Genes : TreeFamSPC24
HOVERGENQ8NBT2
HOGENOMQ8NBT2
Homologs : HomoloGeneSPC24
Homology/Alignments : Family Browser (UCSC)SPC24
Gene fusions - Rearrangements
Tumor Fusion PortalSPC24
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPC24 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPC24
dbVarSPC24
ClinVarSPC24
1000_GenomesSPC24 
Exome Variant ServerSPC24
ExAC (Exome Aggregation Consortium)ENSG00000161888
GNOMAD BrowserENSG00000161888
Genetic variants : HAPMAP147841
Genomic Variants (DGV)SPC24 [DGVbeta]
DECIPHERSPC24 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPC24 
Mutations
ICGC Data PortalSPC24 
TCGA Data PortalSPC24 
Broad Tumor PortalSPC24
OASIS PortalSPC24 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPC24  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPC24
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPC24
DgiDB (Drug Gene Interaction Database)SPC24
DoCM (Curated mutations)SPC24 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPC24 (select a term)
intoGenSPC24
Cancer3DSPC24(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609394   
Orphanet
DisGeNETSPC24
MedgenSPC24
Genetic Testing Registry SPC24
NextProtQ8NBT2 [Medical]
TSGene147841
GENETestsSPC24
Target ValidationSPC24
Huge Navigator SPC24 [HugePedia]
snp3D : Map Gene to Disease147841
BioCentury BCIQSPC24
ClinGenSPC24
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD147841
Chemical/Pharm GKB GenePA162404412
Clinical trialSPC24
Miscellaneous
canSAR (ICR)SPC24 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPC24
EVEXSPC24
GoPubMedSPC24
iHOPSPC24
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:36:12 CET 2017

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