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SPC25 (SPC25, NDC80 kinetochore complex component)

Identity

Other aliasAD024
SPBC25
hSpc25
HGNC (Hugo) SPC25
LocusID (NCBI) 57405
Atlas_Id 57130
Location 2_GL383522v1_alt  [Link to chromosome band 2]
Location_base_pair Starts at 58015 and ends at 77043 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SPC25 (2q31.1) / DHRS9 (2q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPC25   24031
Cards
Entrez_Gene (NCBI)SPC25  57405  SPC25, NDC80 kinetochore complex component
AliasesAD024; SPBC25; hSpc25
GeneCards (Weizmann)SPC25
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr2_GL383522v1_alt:58015-77043 [Contig_View]  SPC25 [Vega]
TCGA cBioPortalSPC25
AceView (NCBI)SPC25
Genatlas (Paris)SPC25
WikiGenes57405
SOURCE (Princeton)SPC25
Genetics Home Reference (NIH)SPC25
Genomic and cartography
GoldenPath hg38 (UCSC)SPC25  -     chr2_GL383522v1_alt:58015-77043 -  2_GL383522v1_alt   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPC25  -     2_GL383522v1_alt   [Description]    (hg19-Feb_2009)
EnsemblSPC25 - 2_GL383522v1_alt [CytoView hg19]  SPC25 - 2_GL383522v1_alt [CytoView hg38]
Mapping of homologs : NCBISPC25 [Mapview hg19]  SPC25 [Mapview hg38]
OMIM609395   
Gene and transcription
Genbank (Entrez)AF225416 AK291093 AY456388 BC022255 CR457197
RefSeq transcript (Entrez)NM_020675
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPC25
Cluster EST : UnigeneHs.421956 [ NCBI ]
CGAP (NCI)Hs.421956
Gene ExpressionSPC25 [ NCBI-GEO ]   SPC25 [ EBI - ARRAY_EXPRESS ]   SPC25 [ SEEK ]   SPC25 [ MEM ]
Gene Expression Viewer (FireBrowse)SPC25 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57405
GTEX Portal (Tissue expression)SPC25
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HBM1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HBM1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HBM1
Splice isoforms : SwissVarQ9HBM1
PhosPhoSitePlusQ9HBM1
Domains : Interpro (EBI)Spc25   
Domain families : Pfam (Sanger)Spindle_Spc25 (PF08234)   
Domain families : Pfam (NCBI)pfam08234   
Conserved Domain (NCBI)SPC25
DMDM Disease mutations57405
Blocks (Seattle)SPC25
PDB (SRS)2VE7    3IZ0   
PDB (PDBSum)2VE7    3IZ0   
PDB (IMB)2VE7    3IZ0   
PDB (RSDB)2VE7    3IZ0   
Structural Biology KnowledgeBase2VE7    3IZ0   
SCOP (Structural Classification of Proteins)2VE7    3IZ0   
CATH (Classification of proteins structures)2VE7    3IZ0   
SuperfamilyQ9HBM1
Peptide AtlasQ9HBM1
IPIIPI00010219   IPI00925465   
Protein Interaction databases
DIP (DOE-UCLA)Q9HBM1
IntAct (EBI)Q9HBM1
BioGRIDSPC25
STRING (EMBL)SPC25
ZODIACSPC25
Ontologies - Pathways
QuickGOQ9HBM1
Ontology : AmiGOcondensed chromosome kinetochore  protein binding  nucleus  cytosol  mitotic spindle organization  chromosome segregation  sister chromatid cohesion  Ndc80 complex  cell division  
Ontology : EGO-EBIcondensed chromosome kinetochore  protein binding  nucleus  cytosol  mitotic spindle organization  chromosome segregation  sister chromatid cohesion  Ndc80 complex  cell division  
NDEx NetworkSPC25
Atlas of Cancer Signalling NetworkSPC25
Wikipedia pathwaysSPC25
Orthology - Evolution
OrthoDB57405
Phylogenetic Trees/Animal Genes : TreeFamSPC25
HOVERGENQ9HBM1
HOGENOMQ9HBM1
Homologs : HomoloGeneSPC25
Homology/Alignments : Family Browser (UCSC)SPC25
Gene fusions - Rearrangements
Tumor Fusion PortalSPC25
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPC25 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPC25
dbVarSPC25
ClinVarSPC25
1000_GenomesSPC25 
Exome Variant ServerSPC25
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP57405
Genomic Variants (DGV)SPC25 [DGVbeta]
DECIPHERSPC25 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPC25 
Mutations
ICGC Data PortalSPC25 
TCGA Data PortalSPC25 
Broad Tumor PortalSPC25
OASIS PortalSPC25 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSPC25  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSPC25
BioMutasearch SPC25
DgiDB (Drug Gene Interaction Database)SPC25
DoCM (Curated mutations)SPC25 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPC25 (select a term)
intoGenSPC25
Cancer3DSPC25(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609395   
Orphanet
DisGeNETSPC25
MedgenSPC25
Genetic Testing Registry SPC25
NextProtQ9HBM1 [Medical]
TSGene57405
GENETestsSPC25
Target ValidationSPC25
Huge Navigator SPC25 [HugePedia]
snp3D : Map Gene to Disease57405
BioCentury BCIQSPC25
ClinGenSPC25
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57405
Chemical/Pharm GKB GenePA162404413
Clinical trialSPC25
Miscellaneous
canSAR (ICR)SPC25 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPC25
EVEXSPC25
GoPubMedSPC25
iHOPSPC25
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:36:12 CET 2017

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