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SPDL1 (spindle apparatus coiled-coil protein 1)

Identity

Alias_namesCCDC99
coiled-coil domain containing 99
Alias_symbol (synonym)FLJ20364
hSpindly
Other alias
HGNC (Hugo) SPDL1
LocusID (NCBI) 54908
Atlas_Id 74156
Location 5q35.1  [Link to chromosome band 5q35]
Location_base_pair Starts at 169583634 and ends at 169604777 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RANBP17 (5q35.1) / SPDL1 (5q35.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SPDL1   26010
Cards
Entrez_Gene (NCBI)SPDL1  54908  spindle apparatus coiled-coil protein 1
AliasesCCDC99
GeneCards (Weizmann)SPDL1
Ensembl hg19 (Hinxton)ENSG00000040275 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000040275 [Gene_View]  chr5:169583634-169604777 [Contig_View]  SPDL1 [Vega]
ICGC DataPortalENSG00000040275
TCGA cBioPortalSPDL1
AceView (NCBI)SPDL1
Genatlas (Paris)SPDL1
WikiGenes54908
SOURCE (Princeton)SPDL1
Genetics Home Reference (NIH)SPDL1
Genomic and cartography
GoldenPath hg38 (UCSC)SPDL1  -     chr5:169583634-169604777 +  5q35.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SPDL1  -     5q35.1   [Description]    (hg19-Feb_2009)
EnsemblSPDL1 - 5q35.1 [CytoView hg19]  SPDL1 - 5q35.1 [CytoView hg38]
Mapping of homologs : NCBISPDL1 [Mapview hg19]  SPDL1 [Mapview hg38]
OMIM616401   
Gene and transcription
Genbank (Entrez)AF269167 AK000371 AK055287 AK074227 AK098009
RefSeq transcript (Entrez)NM_001329639 NM_001329640 NM_001329641 NM_001329642 NM_001329643 NM_017785
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SPDL1
Cluster EST : UnigeneHs.710145 [ NCBI ]
CGAP (NCI)Hs.710145
Alternative Splicing GalleryENSG00000040275
Gene ExpressionSPDL1 [ NCBI-GEO ]   SPDL1 [ EBI - ARRAY_EXPRESS ]   SPDL1 [ SEEK ]   SPDL1 [ MEM ]
Gene Expression Viewer (FireBrowse)SPDL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54908
GTEX Portal (Tissue expression)SPDL1
Human Protein AtlasENSG00000040275-SPDL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96EA4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96EA4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96EA4
Splice isoforms : SwissVarQ96EA4
PhosPhoSitePlusQ96EA4
Domains : Interpro (EBI)SPDLY_chordates   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)SPDL1
DMDM Disease mutations54908
Blocks (Seattle)SPDL1
SuperfamilyQ96EA4
Human Protein Atlas [tissue]ENSG00000040275-SPDL1 [tissue]
Peptide AtlasQ96EA4
HPRD08623
IPIIPI00061356   IPI00030845   IPI00910491   IPI00964310   IPI00965044   IPI00965687   IPI00963965   IPI00967479   IPI00968240   IPI00964852   IPI00975805   
Protein Interaction databases
DIP (DOE-UCLA)Q96EA4
IntAct (EBI)Q96EA4
FunCoupENSG00000040275
BioGRIDSPDL1
STRING (EMBL)SPDL1
ZODIACSPDL1
Ontologies - Pathways
QuickGOQ96EA4
Ontology : AmiGOestablishment of mitotic spindle orientation  spindle pole  condensed chromosome outer kinetochore  protein binding  nucleus  microtubule organizing center  cytosol  sister chromatid cohesion  mitotic metaphase plate congression  enzyme binding  spindle checkpoint  protein localization to kinetochore  kinetochore binding  cell division  
Ontology : EGO-EBIestablishment of mitotic spindle orientation  spindle pole  condensed chromosome outer kinetochore  protein binding  nucleus  microtubule organizing center  cytosol  sister chromatid cohesion  mitotic metaphase plate congression  enzyme binding  spindle checkpoint  protein localization to kinetochore  kinetochore binding  cell division  
NDEx NetworkSPDL1
Atlas of Cancer Signalling NetworkSPDL1
Wikipedia pathwaysSPDL1
Orthology - Evolution
OrthoDB54908
GeneTree (enSembl)ENSG00000040275
Phylogenetic Trees/Animal Genes : TreeFamSPDL1
HOVERGENQ96EA4
HOGENOMQ96EA4
Homologs : HomoloGeneSPDL1
Homology/Alignments : Family Browser (UCSC)SPDL1
Gene fusions - Rearrangements
Tumor Fusion PortalSPDL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSPDL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SPDL1
dbVarSPDL1
ClinVarSPDL1
1000_GenomesSPDL1 
Exome Variant ServerSPDL1
ExAC (Exome Aggregation Consortium)ENSG00000040275
GNOMAD BrowserENSG00000040275
Genetic variants : HAPMAP54908
Genomic Variants (DGV)SPDL1 [DGVbeta]
DECIPHERSPDL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSPDL1 
Mutations
ICGC Data PortalSPDL1 
TCGA Data PortalSPDL1 
Broad Tumor PortalSPDL1
OASIS PortalSPDL1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDSPDL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SPDL1
DgiDB (Drug Gene Interaction Database)SPDL1
DoCM (Curated mutations)SPDL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SPDL1 (select a term)
intoGenSPDL1
Cancer3DSPDL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616401   
Orphanet
DisGeNETSPDL1
MedgenSPDL1
Genetic Testing Registry SPDL1
NextProtQ96EA4 [Medical]
TSGene54908
GENETestsSPDL1
Target ValidationSPDL1
Huge Navigator SPDL1 [HugePedia]
snp3D : Map Gene to Disease54908
BioCentury BCIQSPDL1
ClinGenSPDL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54908
Chemical/Pharm GKB GenePA144596466
Clinical trialSPDL1
Miscellaneous
canSAR (ICR)SPDL1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSPDL1
EVEXSPDL1
GoPubMedSPDL1
iHOPSPDL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:13:11 CET 2017

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